Claudin-4 Overexpression in Epithelial Ovarian Cancer Is Associated with Hypomethylation and Is a Potential Target for Modulation of Tight Junction Barrier Function Using a C-Terminal Fragment of Clostridium perfringens Enterotoxin

Potential Target ◽

Abstract 732: Iron oxide nanoparticles functionalized with the Clostridium Perfringens Enterotoxin carboxi-terminal fragment peptide: A novel diagnostic and therapeutic approach to specifically target ovarian cancer.

10.1158/1538-7445.am2013-732 ◽

2013 ◽

Author(s):

Emiliano Cocco ◽

Ileana Bortolomai ◽

Stefania Bellone ◽

Sara Gasparrini ◽

Diana English ◽

...

Keyword(s):

Ovarian Cancer ◽

Iron Oxide ◽

Iron Oxide Nanoparticles ◽

Clostridium Perfringens ◽

Therapeutic Approach ◽

Oxide Nanoparticles ◽

Clostridium perfringens enterotoxin carboxy-terminal fragment is a novel tumor-homing peptide for human ovarian cancer

BMC Cancer ◽

10.1186/1471-2407-10-349 ◽

2010 ◽

Vol 10 (1) ◽

Cited By ~ 26

Author(s):

Emiliano Cocco ◽

Francesca Casagrande ◽

Stefania Bellone ◽

Christine E Richter ◽

Marta Bellone ◽

...

Keyword(s):

Ovarian Cancer ◽

Clostridium Perfringens ◽

Human Ovarian Cancer ◽

Terminal Fragment ◽

Tumor Homing ◽

Homing Peptide ◽

Carboxy Terminal

Role of Tyr306 in the C-terminal fragment of Clostridium perfringens enterotoxin for modulation of tight junction

Biochemical Pharmacology ◽

10.1016/j.bcp.2006.11.013 ◽

2007 ◽

Vol 73 (6) ◽

pp. 824-830 ◽

Cited By ~ 20

Author(s):

Chiaki Ebihara ◽

Masuo Kondoh ◽

Motoki Harada ◽

Makiko Fujii ◽

Hiroyuki Mizuguchi ◽

...

Keyword(s):

Tight Junction ◽

Clostridium Perfringens ◽

Phosphorylation of Claudin-3 at Threonine 192 by cAMP-dependent Protein Kinase Regulates Tight Junction Barrier Function in Ovarian Cancer Cells

Journal of Biological Chemistry ◽

10.1074/jbc.m502003200 ◽

2005 ◽

Vol 280 (28) ◽

pp. 26233-26240 ◽

Cited By ~ 148

Author(s):

Theresa D'Souza ◽

Rachana Agarwal ◽

Patrice J. Morin

Keyword(s):

Ovarian Cancer ◽

Protein Kinase ◽

Tight Junction ◽

Cancer Cells ◽

Barrier Function ◽

Ovarian Cancer Cells ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

Clostridium Perfringens Enterotoxin

Abstract 364: In vivo targeting of CD44+ ovarian cancer stem cells (CSC) by Clostridium Perfringens Enterotoxin binding domain (CPE-peptide) conjugated to poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NP)

10.1158/1538-7445.am2012-364 ◽

2012 ◽

Cited By ~ 1

Author(s):

Emiliano Cocco ◽

Stefania Bellone ◽

Dana Roque ◽

Federica Guzzo ◽

Sara Gasparrini ◽

...

Keyword(s):

Ovarian Cancer ◽

Stem Cells ◽

Cancer Stem Cells ◽

Clostridium Perfringens ◽

Glycolic Acid ◽

Plga Nanoparticles ◽

Binding Domain ◽

Ovarian Cancer Stem Cells ◽

Computational evaluation of a fusion protein consisted of pertussis toxin and filamentous hemagglutinin from Bordetella pertussis to target Claudin-4 using C-terminal fragment of Clostridium perfringens enterotoxin

Journal of Biomolecular Structure and Dynamics ◽

10.1080/07391102.2020.1794966 ◽

2020 ◽

pp. 1-10

Author(s):

Negar Souod ◽

Elham Rismani ◽

Fariborz Bahrami ◽

Saeed Reza Pakzad ◽

Soheila Ajdary

Keyword(s):

Fusion Protein ◽

Clostridium Perfringens ◽

Pertussis Toxin ◽

Bordetella Pertussis ◽

Computational Evaluation ◽

Terminal Fragment ◽

Filamentous Hemagglutinin

Specificity of Interaction between Clostridium perfringens Enterotoxin and Claudin-Family Tight Junction Proteins

Toxins ◽

10.3390/toxins2071595 ◽

2010 ◽

Vol 2 (7) ◽

pp. 1595-1611 ◽

Cited By ~ 38

Author(s):

Leslie Mitchell ◽

Michael Koval

Keyword(s):

Tight Junction ◽

Clostridium Perfringens ◽

Tight Junction Proteins ◽

Junction Proteins

The application of an alanine-substituted mutant of the C-terminal fragment of Clostridium perfringens enterotoxin as a mucosal vaccine in mice

Biomaterials ◽

10.1016/j.biomaterials.2011.09.048 ◽

2012 ◽

Vol 33 (1) ◽

pp. 317-324 ◽

Cited By ~ 10

Author(s):

Hidehiko Suzuki ◽

Masuo Kondoh ◽

Hideki Kakutani ◽

Seiji Yamane ◽

Hiroshi Uchida ◽

...

Keyword(s):

Clostridium Perfringens ◽

Mucosal Vaccine ◽

Domain mapping of a claudin-4 modulator, the C-terminal region of C-terminal fragment of Clostridium perfringens enterotoxin, by site-directed mutagenesis

Biochemical Pharmacology ◽

10.1016/j.bcp.2007.12.016 ◽

2008 ◽

Vol 75 (8) ◽

pp. 1639-1648 ◽

Cited By ~ 51

Author(s):

Azusa Takahashi ◽

Eriko Komiya ◽

Hideki Kakutani ◽

Takeshi Yoshida ◽

Makiko Fujii ◽

...

Keyword(s):

Clostridium Perfringens ◽

Terminal Region ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Terminal Fragment ◽

Domain Mapping

Role of C-terminal regions of the C-terminal fragment of Clostridium perfringens enterotoxin in its interaction with claudin-4

Journal of Controlled Release ◽

10.1016/j.jconrel.2005.07.008 ◽

2005 ◽

Vol 108 (1) ◽

pp. 56-62 ◽

Cited By ~ 56

Author(s):

Azusa Takahashi ◽

Masuo Kondoh ◽

Akane Masuyama ◽

Makiko Fujii ◽

Hiroyuki Mizuguchi ◽

...

Keyword(s):

Clostridium Perfringens ◽