scholarly journals Translational methods in biostatistics: linear mixed effect regression models of alcohol consumption and HIV disease progression over time

2007 ◽  
Vol 4 (1) ◽  
pp. 8 ◽  
Author(s):  
Mariel M Finucane ◽  
Jeffrey H Samet ◽  
Nicholas J Horton
Author(s):  
Radoslaw Cellmer ◽  
Aneta Cichulska ◽  
Malgorzata Renigier-Bilozor ◽  
Andrzej Bilozor

2020 ◽  
Author(s):  
Yanan Long ◽  
Qi Chen ◽  
Henrik Larsson ◽  
Andrey Rzhetsky

AbstractThe human sex ratio at birth (SRB) is defined as the ratio between the number of newborn boys to the total number of newborns per time unit. It is, typically, slightly greater than (more boys than girls) and fluctuates over time. In this study, we sought to “myth-check” previously reported associations (and test new hypotheses) using variants of mixed-effect regression analyses and time-series models on two very large electronic health record datasets, representing the populations in the United States and Sweden, respectively. Our results revealed that neither dataset supported models in which the SRB changed seasonally or in response to variations in ambient temperature, and that an increased level of a diverse array of pollutants were associated with lower SRBs. Moreover, we found that increased levels of industrial and agricultural activity, which served as proxies for water pollution, were also associated with lower SRBs.


Author(s):  
Suki Yiu ◽  
Diana Archangeli ◽  
Jonathan Yip

This ultrasound study examines the gestural coordination involved in vowel-to-consonant sequences concerning unreleased final stops, which are more susceptible to reduction than their released counterparts. Thus, coarticulatory information on the preceding vowel is important to signal place contrasts of post-vocalic stops. The gestural coordination of vowel-consonant sequences of monosyllabic words in Cantonese represents a testing case for having preserved phonemic contrasts of six unreleased final stops in a range of vowel contexts. Preliminary results from smoothing spline ANOVA and linear mixed-effect regression show that coarticulatory patterns depend on vowel height, that is, non-high vowels are undergoing gradual coarticulation whereas high vowels are phonologising the lingual properties of the unreleased final stops on the preceding vowels.


2020 ◽  
Author(s):  
Antti O Tanskanen ◽  
Mirkka Danielsbacka

Several studies have investigated the association between parental investment and childbearing decisions of adult children. However, studies testing whether changes in parental investment are associated with subsequent changes in fertility intentions over time are lacking. We investigated whether parental investment, measured as contact frequency, emotional closeness, financial support, and childcare, is associated with adult children’s intentions to have a first and a second, or subsequent, child. These associations were studied in four different parent-adult child dyads based on the sex of parents and adult children. We used eight waves from the longitudinal German Family Panel (pairfam) and exploited both between-person and within-person (or fixed-effect) regression models. Between-person associations represent the results across individuals and within-person associations represent an individual’s variation over time (i.e., whether changes in parental investment frequencies are associated with subsequent changes in adult children’s fertility intentions). We found that statistically nonsignificant associations outweighed significant ones. Significant associations were also more often present in the between-person than within-person models. Two of the three significant within-person effects were negative, meaning that when parental investment increased, adult children’s intentions to have a/another child decreased. In between-person models, the parental investment was associated with the childbearing intentions of adult sons rather than those of adult daughters. The present findings indicate that parental investment may not increase adult children’s intentions to have a/another child in Germany.


2003 ◽  
Vol 27 (5) ◽  
pp. 862-867 ◽  
Author(s):  
Jeffrey H. Samet ◽  
Nicholas J. Horton ◽  
Elizabeth T. Traphagen ◽  
Sarah M. Lyon ◽  
Kenneth A. Freedberg

2018 ◽  
Vol 31 (9) ◽  
pp. 1568-1588 ◽  
Author(s):  
Alice Holton ◽  
Fiona Boland ◽  
Paul Gallagher ◽  
Tom Fahey ◽  
Roseanne Kenny ◽  
...  

Objective: The objective of this study was to determine whether trajectories of older adults’ alcohol consumption are influenced by the following life course transitions, relationship status, employment status, and self-rated health. Method: Volume and frequency of drinking were harmonized across first three waves of The Irish Longitudinal Study on Ageing (TILDA; N = 4,295). Multilevel regression models were used to model frequency, average weekly consumption, and heavy episodic drinking. Results: Men and women drank more frequently over time, with frequency decreasing with age for women. Average weekly consumption decreased over time and with increasing age. Transitions in self-rated health, particularly those reflecting poorer health, were associated with lower frequency and weekly consumption. Heavy episodic drinking decreased with age. Men who were retired across all waves were more likely to engage in heavy episodic drinking at baseline. Discussion: Despite the decline in average weekly consumption and heavy episodic drinking, the observed quantities consumed and the increase in frequency of consumption suggest that older Irish adults remain vulnerable to alcohol-related harms.


2013 ◽  
Vol 84 (2) ◽  
pp. 286-291 ◽  
Author(s):  
Young Jae Huh ◽  
Kyung-Hoe Huh ◽  
Hong-Kyun Kim ◽  
Shin-Eun Nam ◽  
Hye Yoon Song ◽  
...  

ABSTRACT Objective: To investigate the constancy of the angle between the Frankfort horizontal plane (FH) and the sella-nasion line (SN) using longitudinal data. Materials and Methods: Longitudinal lateral cephalometric data of 223 children (116 girls and 107 boys) from 6 to 14 years of age were used. The angle between FH and SN (SNFH), the distance from FH to the nasion (NFH), the distance from FH to the sella (SFH), and the differences between the NFH and SFH (Δ) were also measured. All data were analyzed statistically using independent t-tests and mixed-effect regression model analysis. Results: The mean SNFH values showed some minor fluctuations, ranging from 9.26° to 9.74° in girls and 8.45° to 8.95° in boys. The mean NFH and SFH values gradually increased according to age irrespective of sex. There were statistically significant differences by sex for all measurements at several ages. The annual change in SFH and Δ showed sexual dimorphism. Conclusions: There are variations among individuals in the angle between the FH and SN. However, within an individual, the angle does not vary significantly over time during the observation period.


2007 ◽  
Vol 46 (2) ◽  
pp. 194-199 ◽  
Author(s):  
Jeffrey H Samet ◽  
Debbie M Cheng ◽  
Howard Libman ◽  
David P Nunes ◽  
Julie K Alperen ◽  
...  

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