Axis I-Axis II comorbidity of borderline personality disorder: gender-related differences

Borderline personality disorder (BPD) tends to “run in families.” Twin and twin family studies show that BPD is moderately heritable, with some evidence for nonadditive gene action. BPD co-occurs with Axis I and other Axis II disorders, as well as with a certain profile of normal personality traits. Multivariate twin (family) studies have shown that these phenotypic associations are partly due to genetic associations, and this is observed most strongly for BPD and neuroticism. Candidate gene-finding studies for BPD suggest the possible role of genes in the serotonergic and dopaminergic system, but this needs to be confirmed in larger genome-wide studies. Future studies will complement the knowledge described in this chapter to enable us to move toward a comprehensive model of the development of BPD in which biological and environmental influences on BPD are integrated.

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Is borderline personality disorder a mood disorder?

The British Journal of Psychiatry ◽

10.1192/bjp.bp.113.136580 ◽

2014 ◽

Vol 204 (4) ◽

pp. 252-253 ◽

Cited By ~ 10

Author(s):

Gordon Parker

Keyword(s):

Bipolar Disorder ◽

Borderline Personality Disorder ◽

Personality Disorder ◽

Mood Disorder ◽

Mood State ◽

Borderline Personality ◽

Axis Ii ◽

Axis I

SummaryBorderline personality disorder is by its very naming positioned as an Axis II personality disorder and thus seemingly distinct from an Axis I mood state. Clinical differentiation of those with a borderline condition and those with a bipolar disorder is commonly held to be difficult, so raising the question as to whether they may be independent or interdependent conditions, and allowing several possible answers.

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Severity as a Diagnostic Dimension of Borderline Personality Disorder

The Canadian Journal of Psychiatry ◽

10.1177/070674379403900905 ◽

1994 ◽

Vol 39 (9) ◽

pp. 540-544 ◽

Cited By ~ 5

Author(s):

Elsa Marziali ◽

Heather Munroe-Blum ◽

Paul Links

Keyword(s):

Borderline Personality Disorder ◽

Personality Disorder ◽

Diagnostic Interview ◽

Borderline Personality ◽

Specific Pattern ◽

Social Adaptation ◽

Self Report ◽

Axis Ii ◽

Research Interviews ◽

Axis I

The purpose of this study was to identify diagnostic and severity subgroups within a cohort of patients with borderline personality disorder (BPD). Of 171 patients clinically diagnosed with BPD, 132 were Diagnostic Interview for Borderlines (DIB) positive. Through a process of random selection, 41 of the DIB positive subjects were also interviewed with the revised version of the DIB (DIBR) and approximately one half with two semi-structured research interviews, the Schedule for Affective Disorders (SADS) and the Personality Disorder Examination (PDE). All subjects completed four self-report measures of problematic behaviours, symptoms and social adaptation. The analyses included examination of: 1. the correspondence of the BPD diagnosis across the DIB, the DIBR and the PDE; 2. the association between DIBR scoring levels and scores on measures of symptoms and behavioural status; and 3. the co-occurrence of BPD with Axis I and other Axis II disorders. Correlations and analyses of variance between both the DIB and DIBR scoring levels and the scores on the four symptom and behavioural measures showed that the scoring levels (DIB 7 to 10; DIBR 8 to 10) could be used to distinguish three subgroups of BPD. The three groups differed in terms of concordance for BPD with the PDE and in terms of patterns of overlap with DSM-III-R, Axis I and other Axis II disorders. This study shows that BPD subgroups can be located on a continuum of symptomatic and behavioural severity and that each subgroup has a specific pattern of overlap with Axis I and other Axis II disorders.

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Gender Differences in Axis I and Axis II Comorbidity in Patients with Borderline Personality Disorder

Psychopathology ◽

10.1159/000224149 ◽

2009 ◽

Vol 42 (4) ◽

pp. 257-263 ◽

Cited By ~ 50

Author(s):

André Tadi&cacute; ◽

Stefanie Wagner ◽

Julia Hoch ◽

Ömür Ba&scedil;kaya ◽

Robert von Cube ◽

...

Keyword(s):

Gender Differences ◽

Borderline Personality Disorder ◽

Personality Disorder ◽

Borderline Personality ◽

Axis Ii ◽

Axis I

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Comparison of Three Questionnaires to Screen for Borderline Personality Disorder in Adolescents and Young Adults

European Journal of Psychological Assessment ◽

10.1027/1015-5759/a000279 ◽

2017 ◽

Vol 33 (2) ◽

pp. 123-128 ◽

Cited By ~ 5

Author(s):

Anne van Alebeek ◽

Paul T. van der Heijden ◽

Christel Hessels ◽

Melissa S.Y. Thong ◽

Marcel van Aken

Keyword(s):

Young Adults ◽

Borderline Personality Disorder ◽

Personality Disorder ◽

Borderline Personality ◽

Adolescents And Young Adults ◽

Patient Questionnaire ◽

Statistical Manual ◽

Axis Ii ◽

Diagnostic And Statistical Manual ◽

Dsm Iv

Abstract. One of the most common personality disorders among adolescents and young adults is the Borderline Personality Disorder (BPD). The objective of current study was to assess three questionnaires that can reliably screen for BPD in adolescents and young adults (N = 53): the McLean Screening Instrument for BPD (MSI-BPD; Zanarini et al., 2003 ), the Personality Diagnostic Questionnaire 4th edition – BPD scale (PDQ-4 BPD; Hyler, 1994 ), and the SCID-II Patient Questionnaire – BPD scale (SCID-II-PQ BPD). The nine criteria of BPD according to the Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV; APA, 1994 ) were measured with the Structural Clinical Interview for DSM-IV Axis II disorders – BPD scale (SCID-II; First, Spitzer, Gibbon, Williams, & Benjamin, 1995 ). Correlations between the questionnaires and the SCID-II were calculated. In addition, the sensitivity and specificity of the questionnaires were tested. All instruments predicted the BPD diagnosis equally well.

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