If an Entrepreneur Founded the DSM-5 Alternative Model of Personality Disorder: When Axis II Meets Disruptive Innovation

Personality disorder (PD) researchers proposed a highly innovative “paradigm-shifting” revamp for the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5; APA, 2013). Yet, ten years later, Widiger and Hines (this issue) summarize a developmental process plagued by disagreement and stagnation, with little evidence of the field having reaped the desired benefits of this diagnostic revolution. In this commentary, we draw on principles from entrepreneurial creation, operation, and success—positioning the personality disorder scientists in the role of “disruptive innovator”—and summarize key principles from the entrepreneurial process that may be relevant in understanding the challenges and failures of the personality disorder revolution to date.

HiTOP Is Not an Improvement Over the DSM

In their response to our article (both in this issue), DeYoung and colleagues did not sufficiently address three fundamental flaws with the Hierarchical Taxonomy of Psychopathology (HiTOP). First, HiTOP was created using a simple-structure factor-analytic approach, which does not adequately represent the dimensional space of the symptoms of psychopathology. Consequently, HiTOP is not the empirical structure of psychopathology. Second, factor analysis and dimensional ratings do not fix the problems inherent to descriptive (folk) classification; self-reported symptoms are still the basis on which clinical judgments about people are made. Finally, HiTOP is not ready to use in real-world clinical settings. There is currently no empirical evidence demonstrating that clinicians who use HiTOP have better clinical outcomes than those who use the Diagnostic and Statistical Manual of Mental Disorders ( DSM). In sum, HiTOP is a factor-analytic variation of the DSM that does not get the field closer to a more valid and useful taxonomy.

Sociocultural Context and the DSM-5 Alternative Model of Personality Disorder: Comment on Widiger & Hines

Widiger and Hines provide a brief overview of the development of the Alternative Model of Personality Disorder (AMPD) housed within Section 3 of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5; American Psychiatric Association, 2013). They highlight eight issues and controversies related to the AMPD in need of resolution for improvement of both the AMPD model itself as well as the field of personality disorders more broadly. In this brief commentary, I add a ninth issue in need of attention both with respect to the AMPD but also within the field of personality disorders more broadly: 9) How is sociocultural context to be accommodated in AMPD—and more generally personality disorder—theory, research, and treatment? The historical intra-individual, deficit-based models for conceptualizing personality disorders linger in current personality disorder discourse. However, failure to appropriately consider sociocultural context that systematically predisposes wide swaths of the population to unequal access to resources and exposure to psychological stressors, which can impact the appearance of personality pathology, serves to stigmatize minoritized individuals. The personality disorder field, and the AMPD discourse, must appropriately contend with sociocultural context in its models otherwise it risks developing models with limited generalizability and which hold potential to adversely affect sexual and gender minoritized populations, among others.

Surviving Senior Psychopathy: Informant Reports of Deceit and Antisocial Behavior in Multiple Types of Relationships

A prevailing view among researchers and mental health clinicians is that symptoms of antisocial personality disorder (ASPD)/psychopathy decrease as affected individuals reach middle age. In the current investigation, informants were surveyed about the behavior of individuals who they believed showed traits of ASPD/psychopathy and were over the age of 50. A final sample of 1,215 respondents rated the index individuals according to the ASPD/psychopathy traits derived from the pre-publication first draft of the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition, revealing high endorsement of traits associated with ASPD. Survey respondents reported their observations that individuals who met a threshold for putative ASPD/psychopathy continued to engage in antisocial behavior after age 50, and as a result the respondents endured significant harm, including material losses, financial losses, and various self-reported mental health problems. Those who knew the index individuals both before and after the age of 50 were specifically asked whether there was a change in the individual’s engagement in manipulation, deceit, and antisocial behavior; 93% of respondents reported that the behavior was just as bad or worse after age 50. Other researchers have suggested that the DSM diagnostic criteria do not accurately describe ASPD/psychopathy symptoms and behavior in older adults, and that the disorder remains stable, but its manifestation changes with age. This study supports those conclusions.

Intrinsic Brain Activity in Temporal Lobe Epilepsy With and Without Depression: Insights From EEG Microstates

Background: Depression is the most common psychiatric comorbidity of temporal lobe epilepsy (TLE). In the recent years, studies have focused on the common pathogenesis of TLE and depression. However, few of the studies focused on the dynamic characteristics of TLE with depression. We tested the hypotheses that there exist abnormalities in microstates in patients with TLE with depression.Methods: Participants were classified into patients with TLE with depression (PDS) (n = 19) and patients with TLE without depression (nPDS) (n = 19) based upon the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V). Microstate analysis was applied based on 256-channel electroencephalography (EEG) to detect the dynamic changes in whole brain. The coverage (proportion of time spent in each state), frequency of occurrence, and duration (average time of each state) were calculated.Results: Patients with PDS showed a shorter mean microstate duration with higher mean occurrence per second compared to patients with nPDS. There was no difference between the two groups in the coverage of microstate A–D.Conclusion: This is the first study to present the temporal fluctuations of EEG topography in comorbid depression in TLE using EEG microstate analysis. The temporal characteristics of the four canonical EEG microstates were significantly altered in patients with TLE suffer from comorbid depression.

A Closer Look at Supporting Elementary Students With Autism in School

While the educational criteria to be a person impacted by autism will always evolve, implementing educational best practices with fidelity significantly improves the likelihood of a student with autism succeeding in school. This chapter presents a brief overview of the educational criteria for an autism eligibility using the Diagnostic and Statistical Manual, Fifth Edition (DSM-5), a comparison of common characteristics or developmental milestones for typically developing elementary students and students with autism, a summary of standard best practices for elementary students with autism. The chapter provides a few examples of how these best practices can be applied across grade and inclusion-level categories.

Klassifikation von Aufmerksamkeitsdefizit-/Hyperaktivitätsstörungen in der ICD-11

Zusammenfassung. Der Beitrag gibt eine kurze Übersicht über die Veränderungen in der Klassifikation von Hyperkinetischen Störungen und Aufmerksamkeitsdefizit-/Hyperaktivitätsstörungen nach ICD-11 (International Statistical Classification of Diseases and Related Health Problems). Sowohl in der Bezeichnung als auch in der Binnendifferenzierung lehnt sich ICD-11 erfreulicherweise an das DSM-5 (Diagnostic and Statistical Manual of Mental Disorders) an. Auch die Aufgabe der ICD-10-Kombinationsdiagnose der Hyperkinetischen Störung des Sozialverhaltens zugunsten von Mehrfachdiagnosen ist zu begrüßen. Der Verzicht auf eine exakte Operationalisierung der Kriterien hilft einerseits bei der Einordung von Grenzfällen in der klinischen Praxis, macht es aber auch notwendig, für die Klärung der einzelnen Symptome auf das DSM-5 zurückzugreifen.

Gender Disparities in Symptoms of Depression After Medical School Exams and Student Coping Strategies for Postexam Depression Symptoms

CONTEXT Little research exists to determine if medical students experience symptoms of depression after examinations and if symptoms vary by gender. OBJECTIVES Determine if is there a difference between male and female medical students in the number of symptoms of major depressive disorder (MDD) experienced after exams, as well as which coping strategies are used by students to alleviate depression symptoms. METHODS An anonymous and secure survey was sent via university email to first, second, and third-year medical students after exams for 2 consecutive exam periods. Surveys that were not fully completed were excluded from the analysis. RESULTS A total of 162 out of 550 students completed the survey for a response rate of 30%. Overall, a greater proportion of female students experienced more symptoms of depression compared to males. This was statistically significant for the Diagnostic and Statistical Manual of Mental Disorders 5th Edition symptoms of MDD: depressed mood, anhedonia, changes in sleep, fatigue, and difficulty with concentration after exams compared to their male counterparts. Male first-year medical students experienced higher rates of depression compared to their third-year counterparts. Most students exhibited coping strategies that helped them feel less depressed. The 3 most common coping strategies reported were: reaching out to social support networks, physical activity/exercise, and engaging in hobbies. CONCLUSIONS Both gender and year in a medical school play a role in the number of symptoms of depression experienced after medical school exams. Recognizing that examinations can be a trigger of depressive symptoms in medical students, particularly female and first-year students, has important implications on student mental health. Helping students recognize these symptoms and employ healthy coping strategies may further help alleviate these symptoms. Long-term consequences of experiencing symptoms of depression after recurrent exams in medical school are unknown and require further research.

The Quest for Psychiatric Advancement through Theory, Beyond Serendipity

Over the past century, advancements in psychiatric treatments have freed countless individuals from the burden of life-long, incapacitating mental illness. These treatments have largely been discovered by chance. Theory has driven advancement in the natural sciences and other branches of medicine, but psychiatry remains a field in its “infancy”. The targets for healing in psychiatry lie within the realm of the mind’s subjective experience and thought, which we cannot yet describe in terms of their biological underpinnings in the brain. Our technology is sufficiently advanced to study brain neurons and their interactions on an electrophysiological and molecular level, but we cannot say how these form a single feeling or thought. While psychiatry waits for its “Copernican Revolution”, we continue the work in developing theories and associated experiments based on our existing diagnostic systems, for example, the Diagnostic and Statistical Manual of Mental Disorders (DSM), International Classification of Diseases (ICD), or the more newly introduced Research Domain Criteria (RDoC) framework. Understanding the subjective reality of the mind in biological terms would doubtless lead to huge advances in psychiatry, as well as to ethical dilemmas, from which we are spared for the time being.

Różne sposoby definiowania autyzmu. Przegląd stanowisk

Autyzm jest pojęciem wieloznacznym, nieostrym. W nomenklaturze medycznej kilkakrotnie już zmieniał się jego zakres semantyczny. W artykule przedstawiono sposoby występowania tego pojęcia w klasyfikacjach międzynarodowych DSM (Diagnostic and Statistical Manual of Mental Disorders) i ICD (International Statistical Classification of Diseases and Related Health Problems). Cechą wspólną tych definicji jest redukcjonistyczne podejście do pacjenta (jednostki zredukowanej do objawów chorobowych) i myślenie w kategoriach choroby bądź zaburzenia (ASD – Autism Spectrum Disorder). Obecnie istnieją również inne ujęcia autyzmu, o uznanie prawomocności których zabiegają aktorzy społeczni/grupy interesu spoza establishmentu medycznego. W opinii publicznej silnie zakorzenione jest skojarzenie autyzmu z puzzlem bądź kolorem niebieskim spopularyzowane przez fundację Autism Speaks. Ponadto w wydarzeniach medialnych, publikacjach o charakterze popularno-naukowym, naukowym, w tym w literaturze terapeutycznej, coraz częściej występuje określenie „stany ze spektrum autyzmu” (Autism Spectrum Condition). Ukazanie sporu o definicję autyzmu jest istotne, gdyż z argumentacji każdej ze stron wynikają implikacje w stosunku do zdrowia.