scholarly journals A novel Bayesian method for dual-agent Phase I dose-escalation studies using penalized D-optimality

Trials ◽  
2013 ◽  
Vol 14 (S1) ◽  
Author(s):  
Graham Wheeler
Keyword(s):  
Phase I ◽  
Dose Escalation ◽  
Bayesian Method

594 A Phase I Dose-escalation, Pharmacokinetic (PK) and Pharmacodynamic (PD) Evaluation of LY2940680, an Oral Smo Inhibitor

2012 ◽  
Vol 48 ◽  
pp. 182 ◽  
Author(s):  
J. Bendell ◽  
G. Weiss ◽  
J. Infante ◽  
R. Ramanathan ◽  
S. Jones ◽  
...  
Keyword(s):  
Phase I ◽  
Dose Escalation ◽  
Smo Inhibitor

Phase I–II Vinorelbine (Navelbine®) by Continuous Infusion in Patients with Metastatic Breast Cancer: Cumulative Toxicities Limit Dose Escalation

2001 ◽  
Vol 19 (5) ◽  
pp. 459-466 ◽  
Author(s):  
Nuhad K. Ibrahim ◽  
Vicente Valero ◽  
Zia Rahman ◽  
Richard L. Theriault ◽  
Ronald S. Walters ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Metastatic Breast Cancer ◽  
Phase I ◽  
Continuous Infusion ◽  
Dose Escalation ◽  
Metastatic Breast

scholarly journals EP-1577: Prostate cancer SBRT dose escalation to the dominant nodule/s: Phase I and immunological effects

2018 ◽  
Vol 127 ◽  
pp. S849
Author(s):  
F. Herrera ◽  
V. Valerio ◽  
A. Harari ◽  
B. Berthold ◽  
J.Y. Meuwly ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Phase I ◽  
Dose Escalation ◽  
S Phase ◽  
Immunological Effects

A phase I, dose escalation, pharmacodynamic, pharmacokinetic, and food-effect study of α2 integrin inhibitor E7820 in patients with advanced solid tumors

2016 ◽  
Vol 34 (3) ◽  
pp. 329-337 ◽  
Author(s):  
B. Milojkovic Kerklaan ◽  
S. Slater ◽  
M. Flynn ◽  
A. Greystoke ◽  
P. O. Witteveen ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Food Effect ◽  
Effect Study ◽  
Advanced Solid Tumors ◽  
Integrin Inhibitor

scholarly journals A Phase I Dose-Escalation Trial of Single-Fraction Stereotactic Radiation Therapy for Liver Metastases

2015 ◽  
Vol 23 (1) ◽  
pp. 218-224 ◽  
Author(s):  
Jeffrey J. Meyer ◽  
Ryan D. Foster ◽  
Naama Lev-Cohain ◽  
Takeshi Yokoo ◽  
Ying Dong ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Phase I ◽  
Liver Metastases ◽  
Dose Escalation ◽  
Stereotactic Radiation Therapy ◽  
Stereotactic Radiation ◽  
Single Fraction
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