scholarly journals Multicystic urothelial carcinoma of the bladder with gland-like lumina and with signet-ring cells. A case report.

2008 ◽  
Vol 3 (1) ◽  
pp. 36 ◽  
Author(s):  
Isabel Alvarado Cabrero ◽  
Delia Perez Montiel ◽  
Ondrej Hes
Keyword(s):  
Case Report ◽  
Urothelial Carcinoma ◽  
Signet Ring Cells ◽  
Signet Ring ◽  
Carcinoma Of The Bladder

Papillary Urothelial Carcinoma of the Urinary Bladder Demonstrating Prominent Signet-Ring Cells in a Smear

1998 ◽  
Vol 42 (2) ◽  
pp. 407-412 ◽  
Author(s):  
Toshihito Shinagawa ◽  
Mamoru Tadokoro ◽  
Mitsubumi Abe ◽  
Yutaka Koshitaka ◽  
Shoujiroh Kouno ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Urothelial Carcinoma ◽  
Signet Ring Cells ◽  
Signet Ring ◽  
Papillary Urothelial Carcinoma

Cytology Detects Endobronchial Metastasis from Appendiceal Signet-Ring Cell Carcinoma in the Absence of Radiographic Lung Masses: A Case Report

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S44-S44
Author(s):  
B W Taylor ◽  
K Hummel ◽  
Y Xu
Keyword(s):  
Case Report ◽  
Respiratory Distress ◽  
Cell Carcinoma ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Signet Ring Cells ◽  
Endobronchial Metastasis ◽  
Signet Ring ◽  
Ring Cell ◽  
The Right

Abstract Introduction/Objective Endobronchial metastasis (EBM) is uncommon, with a reported prevalence of 2% in cases of non-lung primary malignancies. The most frequently observed carcinomas in EBM are from breast, colon, and renal origins. We present a rare case of endobronchial metastasis from a primary tumor of the appendix without lung masses by computed tomography (CT). Methods/Case Report An 83-year-old woman with signet-ring cell carcinoma of the appendix underwent right hemicolectomy and chemotherapy. Two years later, she returned with intractable nausea and vomiting, and respiratory distress. CT of the chest demonstrated diffuse bilateral pulmonary opacities without lung masses. CT of the abdomen showed peritoneal carcinomatosis. Cytology of ascitic fluid displayed metastasis of the patient’s known appendiceal tumor. Bronchoscopy found significant friable debris appearing to be tumor tissue and occluding multiple bronchioles in the right lung. A bronchoalveolar lavage (BAL) specimen from the right lung was sent for liquid-based cytology, which revealed a few atypical cells with eccentric nuclei and intracytoplasmic vacuoles, abundant macrophages, degenerated mixed inflammatory cells, and scattered bronchial epithelial cells. Cell block demonstrated signet-ring cells mimicking macrophages and infiltrating into small fragments of bronchiolar wall. The signet-ring cells were morphologically similar to those found in the ascitic fluid and the patient’s primary tumor, and were highlighted by mucicarmine stain and immunohistochemical stains for CDX-2 and CK20, but not CK7. Results (if a Case Study enter NA) N/A Conclusion Collectively, the findings supported the diagnosis of endobronchial metastasis of signet-ring cell carcinoma from the lower gastrointestinal tract, i.e. the patient’s known appendiceal primary. Our case demonstrates a rare endobronchial metastasis of a primary neoplasm of the appendix, an important diagnostic consideration when evaluating respiratory distress in patients with such cancer histories. We have described the significant role of BAL cytology to uncover endobronchial metastases without lung masses by CT, and illustrated the finding of signet-ring cells mimicking macrophages in a BAL cytology specimen.

scholarly journals Plasmacytoid Urothelial Carcinoma of the Bladder: Case Report and Review of the Literature

2019 ◽  
Vol 28 (04) ◽  
pp. 333-337
Author(s):  
Ángela Molina Barrera ◽  
Andrea Vásquez Franco ◽  
Andrés Felipe Aristizábal ◽  
David Correa Galeano ◽  
Manuel Cabrales Hessen
Keyword(s):  
Case Report ◽  
Urothelial Carcinoma ◽  
Case Series ◽  
Pelvic Lymphadenectomy ◽  
Ultrasound Finding ◽  
Invasive Potential ◽  
Aggressive Approach ◽  
Urothelial Carcinomas ◽  
Histological Variant ◽  
Carcinoma Of The Bladder

Introduction Plasmacytoid urothelial carcinoma (PUC) of the bladder is a rare histological variant, accounting for 1 to 3% of the invasive urothelial carcinomas, and it is typically aggressive. So far, it has not been well characterized, and the literature is based on reports and case series. Case Report A 70-year-old male patient presenting with 4 months of constitutional and urinary symptoms, with an ultrasound finding of bilateral hydronephrosis and diffuse thickening of the bladder walls. In the cystoscopy, trigone of infiltrated appearance, a biopsy wass performed, whose immunohistochemistry revealed a PUC. The abdominopelvic image showed an infiltrative lesion that compromised the muscle of the bladder and extended to the perivesical fat, without adequate plane of cleavage with the prostate and a single hypogastric adenopathy suspected of malignancy. It was classified as cT3b vs cT4aN1M0 (chest computed tomography [CT] negative for malignancy), and the patient was submitted to a radical cystoprostatectomy, extended pelvic lymphadenectomy and non-continent urinary diversion with ileal conduit. The pathology revealed a diffuse PUC with prostatic stromal involvement and 22 of 39 lymph nodes positive for malignancy. Finally, the patient presented a series of postoperative complications and died. Conclusion Plasmacytoid urothelial carcinoma of the bladder is a rare entity, characterized by high aggressiveness, an advanced stage at the time of diagnosis, and a poor prognosis. Currently, an aggressive approach is recommended due to its high invasive potential.

scholarly journals SLC14A1 (UT-B) gene rearrangement in urothelial carcinoma of the bladder: a case report

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Zhongying Guo ◽  
Xiaobing Niu ◽  
Guangbo Fu ◽  
Baoxue Yang ◽  
Guangping Chen ◽  
...  
Keyword(s):  
Case Report ◽  
Urothelial Carcinoma ◽  
Gene Rearrangement ◽  
Carcinoma Of The Bladder

scholarly journals Primary mucinous adenocarcinoma of the bladder with signet-ring cells: case report

2007 ◽  
Vol 125 (5) ◽  
pp. 297-299 ◽  
Author(s):  
Marcelo Lorenzi Marques ◽  
Gabriel Salum D'Alessandro ◽  
Daher Cezar Chade ◽  
Valéria Pereira Lanzoni ◽  
Samuel Saiovici ◽  
...  
Keyword(s):  
Case Report ◽  
Mucinous Adenocarcinoma ◽  
Rare Case ◽  
Bladder Tumor ◽  
Colorectal Adenocarcinoma ◽  
Signet Ring Cell ◽  
Signet Ring Cells ◽  
Signet Ring ◽  
Ring Cell ◽  
Primary Bladder

CONTEXT: Primary adenocarcinomas of the bladder are uncommon and usually occur by contiguity with or hematogenic dissemination of other adenocarcinomas such as colorectal, prostate and gynecological tract carcinomas. Mucinous and signet-ring cell histological patterns are even rarer and it is often difficult to morphologically distinguish them from metastatic colorectal adenocarcinoma. CASE REPORT: We present and discuss a rare case of primary mucinous adenocarcinoma of the bladder with signet-ring cells in a 57-year-old male patient. Other primary sites for the tumor had been excluded and, in the absence of digestive tract tumor and for confirmation that it was a primary bladder tumor, an immunohistochemistry study was performed.

scholarly journals Polyserositis revealing a signet ring cells gastric adenocarcinoma in a 27 years old male patient: A case report.

2021 ◽  
Author(s):  
Zahid Talibi Alaoui ◽  
Salah Eddine Youbi ◽  
Fatima Ihbibane ◽  
Hind Rachidi ◽  
Fatima Ezzahra Hazmiri ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Emergency Department ◽  
Case Report ◽  
Clinical Improvement ◽  
Gastric Adenocarcinoma ◽  
Male Patient ◽  
Signet Ring Cells ◽  
Signet Ring

Abstract Gastric cancer remains one of the most common and deadly cancers worldwide, especially among old males. It is rare in the younger population (< 30 years old). We describe the case of a 27 years old male patient, presenting to the emergency department, with exsudative polyserositis, initially misdiagnosed and treated as a multifocal tuberculosis with no clinical improvement, later revealing a metastatic signet ring cells gastric adenocarcinoma.

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