scholarly journals Epstein Barr virus DNA analysis in blood predicts disease progression in a rare case of plasmablastic lymphoma with effusion

2013 ◽  
Vol 8 (1) ◽  
pp. 28 ◽  
Author(s):  
Anna Friis ◽  
Börje Åkerlund ◽  
Birger Christensson ◽  
Katarina Gyllensten ◽  
Anna Aleman ◽  
...  
Keyword(s):  
Disease Progression ◽  
Rare Case ◽  
Epstein Barr Virus ◽  
Dna Analysis ◽  
Plasmablastic Lymphoma ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Early detection of nasopharyngeal carcinoma by plasma Epstein-Barr virus DNA analysis in a surveillance program

Cancer ◽  
2013 ◽  
Vol 119 (10) ◽  
pp. 1838-1844 ◽  
Author(s):  
K. C. Allen Chan ◽  
Emily C. W. Hung ◽  
John K. S. Woo ◽  
Paul K. S. Chan ◽  
Sing-Fai Leung ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Early Detection ◽  
Epstein Barr Virus ◽  
Dna Analysis ◽  
Surveillance Program ◽  
Barr Virus ◽  
Epstein Barr

Quantification of plasma Epstein–Barr virus DNA for assessing treatment response in a patient with plasmablastic lymphoma

2011 ◽  
Vol 91 (5) ◽  
pp. 789-791 ◽  
Author(s):  
Man Fai Law ◽  
Wai Lun Poon ◽  
Kwan Shun Ng ◽  
Hay Nun Chan ◽  
Ho Kei Lai ◽  
...  
Keyword(s):  
Treatment Response ◽  
Epstein Barr Virus ◽  
Plasmablastic Lymphoma ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Leishmania infantum and Epstein-Barr virus co-infection in a patient with hemophagocytosis

2017 ◽  
Vol 8 (4) ◽  
Author(s):  
Zied Gaifer ◽  
Mohamed-Rachid Boulassel
Keyword(s):  
Visceral Leishmaniasis ◽  
Complete Resolution ◽  
Liposomal Amphotericin ◽  
Rare Case ◽  
Epstein Barr Virus ◽  
Healthy Male ◽  
High Grade Fever ◽  
Barr Virus ◽  
Epstein Barr ◽  
Ebv Viremia

The authors describe a rare case of a 27-year old previously healthy male presenting with high grade fever, pancytopenia, hepatosplenomegaly, high levels of ferritin and triglyceride, suggesting a diagnosis of hemophagocytic lymphohistiocytosis (HLH) syndrome. Other investigations showed a positive <em>Leishmania</em> <em>infantum</em> serology and high Epstein-Barr virus (EBV) viremia. The diagnosis of a visceral leishmaniasis was confirmed by bone morrow biopsy, which showed Leishman-Donovan bodies and evidence of HLH. The patient received liposomal amphotericin B and he had a complete resolution of his symptoms and clearance of EBV viremia. This case of HLH associated with visceral leishmaniasis and EBV co-infection raises the question about the significance of EBV in patients with HLH. The treatment of actual etiological agent can lead to complete cure while using current recommend chemotherapy for HLH-related EBV in a patient with hidden infection may have deleterious effects.

A Rare Case of Epstein-Barr Virus–Positive T-Cell Lymphoma in the Skin of an Immunocompromised Patient

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Larissa E. van Eijk ◽  
Marjolein J. Koldijk ◽  
Marloes S. van Kester ◽  
Arjan Diepstra ◽  
Gilles F. H. Diercks
Keyword(s):  
T Cell ◽  
Rare Case ◽  
Epstein Barr Virus ◽  
Cell Lymphoma ◽  
Immunocompromised Patient ◽  
T Cell Lymphoma ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Relapse of Plasmablastic Lymphoma With Cutaneous Involvement in an Immunocompetent Male

2020 ◽  
pp. 014556132095219
Author(s):  
Samantha Shwe ◽  
Aditi A. Sharma ◽  
Bonnie A. Lee ◽  
Janellen E. Smith
Keyword(s):  
Nasal Cavity ◽  
Epstein Barr Virus ◽  
Recurrent Disease ◽  
Excisional Biopsy ◽  
Plasmablastic Lymphoma ◽  
Rare Type ◽  
Barr Virus ◽  
Non Hodgkin Lymphoma ◽  
Immunodeficiency Virus ◽  
Epstein Barr

Plasmablastic lymphoma (PBL) is a rare type of non-Hodgkin lymphoma frequently found in the context of immunosuppression and infection with human immunodeficiency virus (HIV) and/or Epstein-Barr virus (EBV). A 33-year-old immunocompetent male presented with recurrent episodes of epistaxis and a growing intranasal mass. Excisional biopsy of the mass revealed an immunohistochemical profile diagnostic of PBL. Upon completion of chemoradiation, he underwent a transnasal endoscopic mucosal flap tissue rearrangement to restore patency for both functional and surveillance purposes. There was no endoscopic evidence of residual or recurrent disease. However, 8 months later, he was found to have a relapse involving the skin. The nasal cavity is one of the most common sites affected by PBL. Involvement of the nasal cavity may present with symptoms of persistent epistaxis accompanied by an enlarging mass. A plasmablastic immunophenotype in combination with HIV or EBV positivity can aid diagnosis.

scholarly journals Epstein–Barr Virus Primary Infection Complicated by Hemophagocytic Lymphohistiocytosis and Plasmablastic Lymphoma in a HIV-Negative Patient

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Nan Chen ◽  
Mike Perez ◽  
Martha Mims
Keyword(s):  
Bone Marrow ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Epstein Barr Virus ◽  
Killer Cell ◽  
High Volume ◽  
Immune Dysregulation ◽  
Gastric Biopsy ◽  
Plasmablastic Lymphoma ◽  
Barr Virus ◽  
Epstein Barr

EBV (Epstein–Barr virus) viremia causes immune dysregulation through various mechanisms, and we are understanding more that mutations in B, T, and NK (natural killer) cell signaling pathways allow EBV complications such as HLH (hemophagocytic lymphohistiocytosis) and lymphomas to arise. Here, we report a 20-year-old previously healthy, HIV- (human immunodeficiency virus-) negative male who presented with fevers, sore throat, and lymphadenopathy (LAD). He was found to have EBV viremia, pancytopenia, and elevated LFTs (liver function tests) suspicious for HLH. Bone marrow biopsy and elevated IL-2 (interleukin) receptor confirmed this diagnosis. Additionally, gastric biopsy confirmed diagnosis of plasmablastic lymphoma (PBL), a rare, aggressive HIV- and EBV-associated lymphoma. Both bone marrow and gastric biopsy showed evidence of EBV. Patients with EBV complications should have a rigorous workup to characterize the full extent of immune dysregulation including genetic testing at a high-volume center.

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