scholarly journals Phylogenetic analysis of Helicobacter pylori cagA gene of Turkish isolates and the association with gastric pathology

Gut Pathogens ◽  
2013 ◽  
Vol 5 (1) ◽  
pp. 33 ◽  
Author(s):  
Barik A Salih ◽  
Bora Bolek ◽  
Mehmet Yildiz ◽  
Soykan Arikan
Keyword(s):  
Phylogenetic Analysis ◽  
Helicobacter Pylori ◽  
Caga Gene ◽  
Gastric Pathology

Diversity of Helicobacter pylori CagA gene and its clinical significance

2001 ◽  
Vol 120 (5) ◽  
pp. A56-A56
Author(s):  
T AZUMA ◽  
Y ITO ◽  
M DOJO
Keyword(s):  
Helicobacter Pylori ◽  
Clinical Significance ◽  
Caga Gene

scholarly journals Mechanism of Metronidazole Resistance inHelicobacter pylori: Comparison of the rdxA Gene Sequences in 30 Strains

2000 ◽  
Vol 44 (8) ◽  
pp. 2207-2210 ◽  
Author(s):  
Nadia Maggi Solcà ◽  
Marco Valerio Bernasconi ◽  
Jean-Claude Piffaretti
Keyword(s):  
Phylogenetic Analysis ◽  
Helicobacter Pylori ◽  
Amino Acid ◽  
Resistant Strain ◽  
Point Mutations ◽  
Housekeeping Genes ◽  
Amino Acid Substitutions ◽  
Metronidazole Resistance ◽  
Nucleotide Mutation ◽  
Nucleotide Insertion

ABSTRACT The rdxA gene of 30 independently isolatedHelicobacter pylori strains was sequenced. A comparison of the rdxA sequences revealed a higher percentage of amino acid substitutions in the corresponding protein than in other housekeeping genes. Out of 122 point mutations, 41 were missense and 4 were nonsense. A resistant strain with a nucleotide insertion in therdxA sequence was also found. With the exception of the point mutations and the insertion generating a stop signal, no particular nucleotide mutation or amino acid substitution could be associated to metronidazole resistance. Moreover, phylogenetic analysis of the 30 nucleotide sequences did not demonstrate specific clusters associated with the resistance phenotype.

scholarly journals Immunohistochemical diagnosis of the cagA-gene genotype of Helicobacter pylori with anti-East Asian CagA-specific antibody

2007 ◽  
Vol 98 (4) ◽  
pp. 521-528 ◽  
Author(s):  
Tomohisa Uchida ◽  
Ryoko Kanada ◽  
Yoshiyuki Tsukamoto ◽  
Naoki Hijiya ◽  
Keiko Matsuura ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Specific Antibody ◽  
East Asian ◽  
Caga Gene ◽  
Immunohistochemical Diagnosis

Prevalence of East Asian (East CagA) and Western variants of the cagA (Western cagA) gene of Helicobacter pylori in Yakutia

2021 ◽  
pp. 63-67
Author(s):  
N.N. Gotovsev ◽  
N.A. Barashkov ◽  
V.G. Pshennikova ◽  
M.V. Pak ◽  
K.C. Loskutova ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
East Asian ◽  
Caga Gene
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