scholarly journals Long-term psychological effects of a no-sedation protocol in critically ill patients

Critical Care ◽  
2011 ◽  
Vol 15 (6) ◽  
pp. R293 ◽  
Author(s):  
Thomas Strøm ◽  
Mette Stylsvig ◽  
Palle Toft
Critical Care ◽  
2011 ◽  
Vol 15 (S1) ◽  
Author(s):  
T Strøm ◽  
M Stylsvig ◽  
P Toft

2003 ◽  
Vol 168 (12) ◽  
pp. 1457-1461 ◽  
Author(s):  
John P. Kress ◽  
Brian Gehlbach ◽  
Maureen Lacy ◽  
Neil Pliskin ◽  
Anne S. Pohlman ◽  
...  

2012 ◽  
Vol 32 (1) ◽  
pp. 43-51 ◽  
Author(s):  
Elizabeth Berry ◽  
Heather Zecca

The continuous infusion of sedative agents is often necessary for critically ill patients. However, it has been associated with several disadvantages. Numerous interventions to reduce these risks have been evaluated, including the practice of interrupting sedative infusions on a daily basis. A literature search was conducted, and 7 studies were reviewed to evaluate the safety and effectiveness of daily interruption of sedative infusions and its outcomes. The implementation of daily sedation interruptions was suggested to minimize multiple complications associated with continuous sedative infusions and was not associated with intensive care–related complications or long-term psychological effects. Additional studies have revealed perceived barriers to the implementation of daily sedation interruptions. Further randomized controlled trials enrolling larger, more diverse samples are needed to provide more evidence regarding the safety and effectiveness of this intervention.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Johanna Helmersson-Karlqvist ◽  
Miklos Lipcsey ◽  
Johan Ärnlöv ◽  
Max Bell ◽  
Bo Ravn ◽  
...  

AbstractDecreased glomerular filtration rate (GFR) is linked to poor survival. The predictive value of creatinine estimated GFR (eGFR) and cystatin C eGFR in critically ill patients may differ substantially, but has been less studied. This study compares long-term mortality risk prediction by eGFR using a creatinine equation (CKD-EPI), a cystatin C equation (CAPA) and a combined creatinine/cystatin C equation (CKD-EPI), in 22,488 patients treated in intensive care at three University Hospitals in Sweden, between 2004 and 2015. Patients were analysed for both creatinine and cystatin C on the same blood sample tube at admission, using accredited laboratory methods. During follow-up (median 5.1 years) 8401 (37%) patients died. Reduced eGFR was significantly associated with death by all eGFR-equations in Cox regression models. However, patients reclassified to a lower GFR-category by using the cystatin C-based equation, as compared to the creatinine-based equation, had significantly higher mortality risk compared to the referent patients not reclassified. The cystatin C equation increased C-statistics for death prediction (p < 0.001 vs. creatinine, p = 0.013 vs. combined equation). In conclusion, this data favours the sole cystatin C equation rather than the creatinine or combined equations when estimating GFR for risk prediction purposes in critically ill patients.


2020 ◽  
Vol 13 (9) ◽  
pp. 550-556
Author(s):  
Minal Karavadra ◽  
Ricky Bell

The intensive care department may seem a long way from the GP's consulting room, but every year tens of thousands of critically ill patients are admitted to intensive care units (ICUs) across the UK. Patients are often left with long term sequelae that may require GP input. Physical weakness, psychiatric disturbance and cognitive decline are not uncommon after an illness that requires a stay in an ICU. These hinder a patient’s return to their previous level of function and impact caregivers after discharge. This article aims to highlight the chronic symptoms patients can acquire during ICU admission that may come to the attention of GPs for their advice and treatment.


2005 ◽  
Vol 116 (1) ◽  
pp. 15-24 ◽  
Author(s):  
Gunnar Nilsson ◽  
Jan Astermark ◽  
Stefan Lethagen ◽  
Einar Vernersson ◽  
Erik Berntorp

2013 ◽  
Vol 186 (2) ◽  
pp. E95-E102 ◽  
Author(s):  
S. M. Bagshaw ◽  
H. T. Stelfox ◽  
R. C. McDermid ◽  
D. B. Rolfson ◽  
R. T. Tsuyuki ◽  
...  

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