The Yorkshire Cancer Research ACTION pilot trial of Acceptance and Commitment Therapy for women with breast cancer to support wellbeing and hormone therapy medication decisions

2020 ◽  
Author(s):  
Rachel Ellison ◽  
Samuel Smith
Keyword(s):  
Breast Cancer ◽  
Cancer Research ◽  
Hormone Therapy ◽  
Acceptance And Commitment Therapy ◽  
Pilot Trial ◽  
Commitment Therapy ◽  
Acceptance And Commitment ◽  
Medication Decisions ◽  
Research Action

scholarly journals Acceptance and commitment therapy for fatigue interference in advanced gastrointestinal cancer and caregiver burden: protocol of a pilot randomized controlled trial

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Catherine E. Mosher ◽  
Ekin Secinti ◽  
Kurt Kroenke ◽  
Paul R. Helft ◽  
Anita A. Turk ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Family Caregivers ◽  
Acceptance And Commitment Therapy ◽  
Caregiver Burden ◽  
Pilot Trial ◽  
Mental Health Service Use ◽  
Link Type ◽  
Commitment Therapy ◽  
Gi Cancer ◽  
Acceptance And Commitment

Abstract Background Fatigue interference with activities, mood, and cognition is one of the most prevalent and bothersome concerns of advanced gastrointestinal (GI) cancer patients. As fatigue interferes with patient functioning, family caregivers often report feeling burdened by increasing responsibilities. Evidence-based interventions jointly addressing cancer patient fatigue interference and caregiver burden are lacking. In pilot studies, acceptance and commitment therapy (ACT) has shown promise for addressing symptom-related suffering in cancer patients. The current pilot trial seeks to test a novel, dyadic ACT intervention for both advanced GI cancer patients with moderate-to-severe fatigue interference and their family caregivers with significant caregiving burden or distress. Methods A minimum of 40 patient-caregiver dyads will be randomly assigned to either the ACT intervention or an education/support control condition. Dyads in both conditions attend six weekly 50-min telephone sessions. Outcomes are assessed at baseline as well as 2 weeks and 3 months post-intervention. We will evaluate the feasibility, acceptability, and preliminary efficacy of ACT for improving patient fatigue interference and caregiver burden. Secondary outcomes include patient sleep interference and patient and caregiver engagement in daily activities, psychological flexibility, and quality of life. We will also explore the effects of ACT on patient and caregiver physical and mental health service use. Discussion Findings will inform a large-scale trial of intervention efficacy. Results will also lay the groundwork for further novel applications of ACT to symptom interference with functioning and caregiver burden in advanced cancer. Trial Registration ClinicalTrials.gov, NCT04010227. Registered 8 July 2019.

Efficacy of telehealth acceptance and commitment therapy for weight loss: a pilot randomized clinical trial

2021 ◽  
Author(s):  
Jonathan B Bricker ◽  
Kristin E Mull ◽  
Brianna M Sullivan ◽  
Evan M Forman
Keyword(s):  
Weight Loss ◽  
Acceptance And Commitment Therapy ◽  
Behavioral Therapy ◽  
Pilot Trial ◽  
Population Level ◽  
Baseline Body Mass Index ◽  
Commitment Therapy ◽  
Acceptance And Commitment ◽  
Telephone Coaching

Abstract Telehealth coaching for weight loss has high population-level reach but limited efficacy. To potentially improve on this limitation, the purpose of this study was to determine the preliminary efficacy of the first known telephone coaching acceptance and commitment therapy (ACT) intervention for weight loss. A two-arm, stratified, individually randomized pilot trial comparing ACT (n = 53) with standard behavioral therapy (SBT; n = 52) was used for this study. Both interventions were delivered in 25 telephone coaching calls (15–20 min each) over a 12 month period. Weight was measured at baseline and 3, 6, and 12 month postrandomization follow-ups. Recruited from 32 U.S. states, participants were of mean age 40.7, 42% male, 34% racial/ethnic minority, and mean baseline body mass index of 34.3. Fractions of 10% or more scale-reported weight loss: 15% for ACT versus 4% for SBT at 3 month follow-up (N = 86; odds ratio [OR] = 4.61; 95% confidence interval [CI]: 0.79, 26.83), 24% for ACT versus 13% for SBT at 6 month follow-up (N = 72; OR = 2.45; 95% CI: 0.65, 9.23), 30% for ACT versus 30% for SBT at 12 month follow-up (N = 57; OR = 0.93; 95% CI: 0.28, 3.09). Fractions of 10% or more self-reported weight loss at 12 month follow-up: 25% for ACT versus 15% for SBT (N = 75; OR = 2.38; 95% CI: 0.68, 8.34). The conclusion of the study was the preliminary evidence that telephone coaching ACT may be efficacious for weight loss.

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