The safety and efficacy of an herbal chlorhexidine gel on bad breath caused by oral bacteria

The spread of the COVID-19 virus has shaken the world. The application of Clean and Healthy Living Behavior (CHLB) is the best effort to prevent the transmission of the Covid-19 virus. Maintaining oral and dental hygiene can improve health, especially during the COVID-19 pandemic. Sarang Banua (Clerodendrum fragrans Vent Willd) is a local plant of North Sumatra, containing secondary metabolites of alkaloids, steroids, flavonoids, triterpenoids, saponins, tannins, and quinones that have bioactivity such as antibacterial and antioxidant. The preparation of Sarang Banua mouthwash (SABANA) made from the extract of the sarang banua leaves with a concentration of 0.5 grams in 100 ml of preparation (0.5%) has been formulated, evaluated by organoleptic, pH and antibacterial test. The results of organoleptic and pH tests showed that SABANA mouthwash preparations were brown and slightly cloudy, tasted very distinctive, fresh, and eliminated bad breath with a pH of 7 in accordance with quality standards. About 70% of the panelists stated that they really liked the color, aroma, taste and appearance of SABANA mouthwash preparations. The results of antibacterial test against the oral bacteria Streptococcus mutans ATCC (25175) showed that 0.5% and 0.75% of the oral antibacterial mouthwash was found to be effective as oral antibacterial with an average inhibition zone diameter of 16.55 and 16.9 mm. Through the activities of the Student Creativity-Entrepreneurship Program, SABANA mouthwash have been produced and marketed in the local as well as outside the city by online and offline-shop and have the opportunity to develop into a new entrepreneur.

Download Full-text

Recolonization of Mutans Streptococci after Application of Chlorhexidine Gel

Brazilian Dental Journal ◽

10.1590/0103-6440201300156 ◽

2014 ◽

Vol 25 (6) ◽

pp. 485-488 ◽

Cited By ~ 4

Author(s):

Glauber Campos Vale ◽

Altair Antoninha Del Bel Cury ◽

Rodrigo Alex Arthur ◽

Jaime Aparecido Cury ◽

Cínthia Pereira Machado Tabchoury

Keyword(s):

Streptococcus Mutans ◽

Healthy Adult ◽

Oral Bacteria ◽

Mutans Streptococci ◽

Intensive Treatment ◽

Blood Agar ◽

Gel Treatment ◽

Adult Volunteers ◽

Chlorhexidine Gel

Streptococcus mutans is specifically suppressed by intensive treatment with chlorhexidine gel, but the time for recolonization and the effect on other oral bacteria are not totally clear. In this study, recolonization of mutans streptococci was evaluated in nine healthy adult volunteers, who were highly colonized with this microorganism. Stimulated saliva was collected before (baseline) and at 1, 7, 14, 21 and 28 days after application of 1% chlorhexidine gel on volunteers' teeth for two consecutive days. On each day, the gel was applied using disposable trays for 3 x 5 min with intervals of 5 min between each application. Saliva was plated on blood agar to determine total microorganisms (TM); on mitis salivarius agar to determine total streptococci (TS) and on mitis salivarius agar plus bacitracin to determine mutans streptococci (MS). Chlorhexidine was capable of reducing the counts of MS and the proportion of MS with regard to total microorganisms (%MS/TM) (p<0.05), but these values did not differ statistically from baseline (p>0.05) after 14 days for MS and 21 days for %MS/TM. The counts of TM and TS and the proportion of MS to total streptococci did not differ statistically from baseline (p>0.05) after chlorhexidine treatment. The results suggest that the effect of chlorhexidine gel treatment on suppression of mutans streptococci is limited to less than a month in highly colonized individuals.

Download Full-text

Contemporary methods and mobile denture cleansers and theirs significance for older population

Medicinski pregled ◽

10.2298/mpns1110497s ◽

2011 ◽

Vol 64 (9-10) ◽

pp. 497-502 ◽

Cited By ~ 1

Author(s):

Ljiljana Strajnic ◽

Miodrag Djokic ◽

Predrag Vucinic

Keyword(s):

Oral Bacteria ◽

Gastrointestinal Infections ◽

Denture Base ◽

Hospitalized Elderly ◽

Bad Breath ◽

Bacterial Plaque ◽

Micro Organisms ◽

Denture Cleansers ◽

Vulnerable Elderly

Introduction. A dramatic increase in the number of people living in their seventies, eighties and nineties is associated with a loss of teeth and the use of mobile dentures. The aim of this paper was to highlight the consequences of poor denture hygiene on oral and general health in vulnerable elderly people, in long-term hospitalized elderly patients and in long-term institutionalized elderly in nursing homes. Denture deposits and consequences of poor denture hygiene. The number of bacteria living in the mouth is getting larger after putting denture on. Namely, a small ?space? develops between jaw and denture, creating perfect conditions for bacterial growth. Denture becomes a ?reservoir? of micro-organisms. Denture deposits such as bacterial plaque, fungi, tartar and remnants could be responsible for: stomatitis prothetica, cheilitis angularis, inflammatory fibrous hyperplasia, halitosis (bad breath), dental caries in mobile denture carriers, mucositis and periimplantitis in mobile implant over-dentures carriers, accelerated destruction of denture materials for underlying, such as denture base soft liners, respiratory airways diseases, bacterial endocarditis and gastrointestinal infections. Removal of denture deposits. It is recommendable to combine mechanical and chemical denture cleaning. Denture submersion into a commercial cleansing solution for less than one hour is an effective cleaning method. Commercial cleansers specifically intended for dentures with metal parts should be used for those dentures. Commercial cleansers with a new component of silicon polymer, whose thin layer surrounds all denture surfaces and disables oral bacteria to agglomerate, are effective and useful. Preventive hygienic treatments are very important in hospitals and homes for the aged, bearing in mind that old and ill persons reside here. Those institutions are recommended to get equipped with ultrasound denture cleaners. Importance of written brochure on proper denture hygiene. Patients should be verbally instructed and showed about cleaning techniques, but also written instructions in form of brochure should be distributed in order to achieve better effects.

Download Full-text

Attachment of oral bacteria to titanium surfaces: An SEM study

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100170074 ◽

1994 ◽

Vol 52 ◽

pp. 468-469

Author(s):

J. E. Laffoon ◽

R. L. Anderson ◽

J. C. Keller ◽

C. D. Wu-Yuan

Keyword(s):

Technical Problem ◽

Titanium Implant ◽

Oral Bacteria ◽

Bacterial Cells ◽

Thin Sections ◽

Surface Ultrastructure ◽

Sem Study ◽

Key Factor ◽

Titanium Surfaces

Titanium (Ti) dental implants have been used widely for many years. Long term implant failures are related, in part, to the development of peri-implantitis frequently associated with bacteria. Bacterial adherence and colonization have been considered a key factor in the pathogenesis of many biomaterial based infections. Without the initial attachment of oral bacteria to Ti-implant surfaces, subsequent polymicrobial accumulation and colonization leading to peri-implant disease cannot occur. The overall goal of this study is to examine the implant-oral bacterial interfaces and gain a greater understanding of their attachment characteristics and mechanisms. Since the detailed cell surface ultrastructure involved in attachment is only discernible at the electron microscopy level, the study is complicated by the technical problem of obtaining titanium implant and attached bacterial cells in the same ultra-thin sections. In this study, a technique was developed to facilitate the study of Ti implant-bacteria interface.Discs of polymerized Spurr’s resin (12 mm x 5 mm) were formed to a thickness of approximately 3 mm using an EM block holder (Fig. 1). Titanium was then deposited by vacuum deposition to a film thickness of 300Å (Fig. 2).

Download Full-text