The anthelmintic resistance has limited the control of gastrointestinal nematodes of small ruminants and thus has awakened
interest in the study of plants extract as a source of anthelmintics. These experiments were carried out to evaluate the in
vitro efficacy of Jatrophacurcas latex extract against Haemonchuscontortus larval motility. To evaluate the larvicidal
activity, H.contortus L3 were incubated with the extracts with varying concentration of 5 mg/mL, 10 mg/mL, 15 mg/mL
and 20 mg/mL at 27°C for 48, 72 and 96 hrs. The results were subjected to the Kruskal-Wallis test (P less than 0.05). The extracts
showed dose-dependent larvicidal effects. These results suggest that J.curcas can be used to control gastrointestinal
nematodes of small ruminants.
Development of marker-free transgenic Jatropha curcas producing curcin-deficient seeds through endosperm-specific RNAi-mediated gene silencing
