scholarly journals Maternal vitamin D status, gestational diabetes and infant birth size

2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Helena H. Hauta-alus ◽  
Heli T. Viljakainen ◽  
Elisa M. Holmlund-Suila ◽  
Maria Enlund-Cerullo ◽  
Jenni Rosendahl ◽  
...  

2018 ◽  
Vol 45 (1) ◽  
pp. 291-300 ◽  
Author(s):  
Lingmin Hu ◽  
Yue Zhang ◽  
Xing Wang ◽  
Lianghui You ◽  
Pengfei Xu ◽  
...  

Background/Aims: Whether maternal vitamin D deficiency is associated with gestational diabetes remains controversial. This meta-analysis aimed to systematically evaluate published evidence on the association between maternal vitamin D status and the risk of gestational diabetes. Methods: We retrieved relevant articles from the PubMed, Medline and Embase databases up to May 2017 for observational studies investigating the association between vitamin D status and the risk of gestational diabetes. Odds ratios (OR) or risk ratios (RR) from individual studies were pooled using the fixed and random effect models. Results: The meta-analysis of 29 observational studies included 28,982 participants, of which 4,634 were diagnosed with gestational diabetes, and showed that maternal vitamin D insufficiency was associated with a significantly increased risk of gestational diabetes by 39% (pooled OR = 1.39, 95%CI = 1.20-1.60) with moderate heterogeneity (I2 = 50.2%; P = 0.001). Moreover, the 25(OH)D level was significantly lower in gestational diabetes cases than in controls with a pooled effect of -4.79 nmol/L (95% CI = -6.43, -3.15). Significant heterogeneity was also detected (I2 = 65.0%, P < 0.001). Further subgroup analysis indicated that this association was also evident in most subpopulations. Conclusion: This meta-analysis indicated a significant association between vitamin D insufficiency and increased risk of gestational diabetes. Further well-designed large-scale clinical trials are essential to verify this association.



2010 ◽  
Vol 25 (5) ◽  
pp. 524-527 ◽  
Author(s):  
Sedigheh Soheilykhah ◽  
Mahdieh Mojibian ◽  
Maryam Rashidi ◽  
Soodabeh Rahimi-Saghand ◽  
Fatemeh Jafari




2015 ◽  
Vol 15 (2) ◽  
pp. 523 ◽  
Author(s):  
N Mutlu ◽  
H Esra ◽  
A Begum ◽  
D Fatma ◽  
Y Arzu ◽  
...  




2016 ◽  
Vol 116 (4) ◽  
pp. 621-631 ◽  
Author(s):  
Yi Lin Ong ◽  
Phaik Ling Quah ◽  
Mya Thway Tint ◽  
Izzuddin M. Aris ◽  
Ling Wei Chen ◽  
...  

AbstractMaternal vitamin D status during pregnancy has been associated with infant birth and postnatal growth outcomes, but reported findings have been inconsistent, especially in relation to postnatal growth and adiposity outcomes. In a mother–offspring cohort in Singapore, maternal plasma vitamin D was measured between 26 and 28 weeks of gestation, and anthropometric measurements were obtained from singleton offspring during the first 2 years of life with 3-month follow-up intervals to examine birth, growth and adiposity outcomes. Associations were analysed using multivariable linear regression. Of a total of 910 mothers, 13·2 % were vitamin D deficient (<50 nmol/l) and 26·5 % were insufficient (50–75 nmol/l). After adjustment for potential confounders and multiple testing, no statistically significant associations were observed between maternal vitamin D status and any of the birth outcomes – small for gestational age (OR 1·00; 95 % CI 0·56, 1·79) and pre-term birth (OR 1·16; 95 % CI 0·64, 2·11) – growth outcomes – weight-for-age z-scores, length-for-age z-scores, circumferences of the head, abdomen and mid-arm at birth or postnatally – and adiposity outcomes – BMI, and skinfold thickness (triceps, biceps and subscapular) at birth or postnatally. Maternal vitamin D status in pregnancy did not influence infant birth outcomes, postnatal growth and adiposity outcomes in this cohort, perhaps due to the low prevalence (1·6 % of the cohort) of severe maternal vitamin D deficiency (defined as of <30·0 nmol/l) in our population.



2012 ◽  
Vol 28 (2) ◽  
pp. 164-168 ◽  
Author(s):  
Arthur M. Baker ◽  
Sina Haeri ◽  
Carlos A. Camargo ◽  
Alison M. Stuebe ◽  
Kim A. Boggess




2011 ◽  
Vol 204 (1) ◽  
pp. S103-S104 ◽  
Author(s):  
Arthur Baker ◽  
Sina Haeri ◽  
Carlos Camargo ◽  
Alison M. Stuebe ◽  
Kim Boggess


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