scholarly journals A case of bilateral acute depigmentation of the Iris in one of two identical twins

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Spencer Langevin ◽  
Alexandra Gershkovich ◽  
Brian P. Marr
Keyword(s):  
Chronic Migraine ◽  
Plant Extract ◽  
Anterior Segment ◽  
Case Series ◽  
Identical Twin ◽  
Pigment Dispersion ◽  
Pitcher Plant ◽  
Twin Sister ◽  
Pigment Dispersion Syndrome ◽  
History Of

Abstract Background Bilateral Acute Depigmentation of the Iris (BADI) is a condition which was first described in a case series from Turkey by Tugal-Tutkin and Urgancioglu in (Graefes Arch Clin Exp Ophthalmol 244:742-6, 2006). The condition is characterized by bilateral acute depigmentation and discoloration of the iris stroma, pigment dispersion, and deposition of pigment in the angle. In our case we report a patient who developed BADI after receiving pitcher plant extract injections for chronic migraine, while her identical twin sister has normal iris architecture and pigmentation and never received any pitcher plant injections. Case presentation Patient is a 41-year-old female with history of pitcher plant extract injections to her face for chronic migraine, who later developed bilateral depigmentation of the iris. She did not have any signs of anterior segment uveitis or iridocyclitis. She has an identical twin sister who maintained normal iris pigmentation during the entire course. Conclusions Bilateral Acute depigmentation of the is a recently discovered condition described in the literature in Turkish patients (Tugal-Tutkun and Urgancioglu, Graefes Arch Clin Exp Ophthalmol 244:742-6, 2006; Tugal-Tutkun et al., Ophthalmology 116(8):1552-7, 2009). This condition affects mainly young females and is characterized by acute bilateral stromal depigmentation, without other pathologic ocular findings. These patients usually maintain normal vision and do not develop significant glaucoma from pigment collecting in the anterior chamber angle. This condition can be mistaken for Fuchs’ heterochromic iridocyclitis, pigment dispersion syndrome, pseudoexfoliation syndrome, and viral iridocyclitis. This is the first reported case in North America and is important for differentiation from the above pathologies. Our patient had a history of pitcher plant extract injections to the face but it is unclear if this is associated with our patient’s development of BADI. As awareness of this condition progresses, a possible etiology may be elucidated.

scholarly journals A Case of Bilateral Acute Depigmentation of the Iris in One of Two Identical Twins

2019 ◽  
Author(s):  
Spencer Langevin ◽  
Alexandra Gershkovich ◽  
Brian P Marr
Keyword(s):  
Chronic Migraine ◽  
Plant Extract ◽  
Anterior Segment ◽  
Case Series ◽  
Identical Twin ◽  
Pigment Dispersion ◽  
Pitcher Plant ◽  
Twin Sister ◽  
Pigment Dispersion Syndrome ◽  
History Of

Abstract Background: Bilateral Acute Depigmentation of the Iris (BADI) is a condition which was first described in a case series from Turkey by Tugal-Tutkin and Urgancioglu in 2006.1 The condition is characterized by bilateral acute depigmentation and discoloration of the iris stroma, pigment dispersion, and deposition of pigment in the angle. In our case we report a patient who developed BADI after receiving pitcher plant extract injections for chronic migraine, while her identical twin sister has normal iris architecture and pigmentation and never received any pitcher plant injections. Case Presentation: Patient is a 41-year-old female with history of pitcher plant extract injections to her face for chronic migraine, who later developed bilateral depigmentation of the iris. She did not have any signs of anterior segment uveitis or iridocyclitis. She has an identical twin sister who maintained normal iris pigmentation during the entire course. Discussions and Conclusion: Bilateral Acute depigmentation of the is a recently discovered condition described in the literature in Turkish patients1,2. This condition affects mainly young females and is characterized by acute bilateral stromal depigmentation, without other pathologic ocular findings. These patients usually maintain normal vision and do not develop significant glaucoma from pigment collecting in the anterior chamber angle. This condition can be mistaken for Fuchs’ heterochromic iridocyclitis, pigment dispersion syndrome, pseudoexfoliation syndrome, and viral iridocyclitis. This is the first reported case in North America and is important for differentiation from the above pathologies. Our patient had a history of pitcher plant extract injections to the face but it is unclear if this is associated with our patient’s development of BADI. As awareness of this condition progresses, a possible etiology may be elucidated.

scholarly journals A Case of Bilateral Acute Depigmentation of the Iris in One of Two Identical Twins

2019 ◽  
Author(s):  
Spencer Langevin ◽  
Alexandra Gershkovich ◽  
Brian P Marr
Keyword(s):  
Chronic Migraine ◽  
Anterior Segment ◽  
Case Series ◽  
Invasive Procedure ◽  
Pigment Dispersion ◽  
Young Females ◽  
Pigment Dispersion Syndrome ◽  
The Face ◽  
History Of ◽  
Iris Pigmentation

Abstract Background: Bilateral Acute Depigmentation of the Iris (BADI) is a condition which was first described in a case series from Turkey by Tugal-Tutkin and Urgancioglu in 2006.1 The condition is characterized by bilateral acute depigmentation and discoloration of the iris stroma, pigment dispersion, and deposition of pigment in the angle. In our case we report one of two identical twin sisters who developed BADI after receiving sarapin injections for chronic migraine, while the other has normal iris architecture and pigmentation and never received any like invasive procedure. Case Presentation: Patient is a 41 year old female with history of Sarapin injections to her face for chronic migraine who later developed bilateral depigmentation of the iris. She did not have any signs of anterior segment uveitis or iridocyclitis. She has a twin sister who maintained normal iris pigmentation during the entire course. Discussions and Conclusion: Bilateral Acute depigmentation of the iris is a recently discovered condition described in the literature in Turkish patients1,2. This condition affects mainly young females and is characterized by acute bilateral stromal depigmentation without other pathologic ocular findings. These patients usually maintain normal vision and do not develop significant glaucoma from pigment collecting in the anterior chamber angle. This condition can be mistaken for Fuch’s heterochromic iridocyclitis, pigment dispersion syndrome, pseudoexfoliation syndrome, viral iridocyclitis, VZV, HSV, and CMV. This is the first reported case in North America and is important for differentiation of the above pathologies. Our patient had a history of Sarapin injections to the face but it is unsure if this is associated with our patient’s development of BADI. As awareness of this condition progresses a possible etiology may be elucidated. Keywords: Iris; depigmentation; Sarapin, iris transillumination.

scholarly journals Anterior segment optical coherence tomography documentation of Reverse Pupillary Block -A case of Pigment Dispersion Syndrome in a 10 year Old Child

2016 ◽  
Vol 15 (1) ◽  
pp. 34-39
Author(s):  
Devendra Maheshwari ◽  
Renagappa Ramakrishnan ◽  
Neelam Pawar
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Segment ◽  
Pigment Dispersion ◽  
Optical Coherence ◽  
Laser Peripheral Iridotomy ◽  
Pupillary Block ◽  
Laser Iridotomy ◽  
Pigment Dispersion Syndrome ◽  
History Of ◽  
Peripheral Iridotomy

We report a 10-year-old boy with unusually dense, bilateral central posterior capsule pigmentation associated with the characteristic clinical features of pigment dispersion syndrome, including Krukenberg’s spindle and dense trabecular pigmentation in both eyes. There was no history of trauma , laser or intraocular surgeries . The presence of posterior or backward bowing of iris suggested a reverse pupillary block mechanism of pigment dispersion syndrome. Nd Yag laser peripheral iridotomy was performed in both eyes to relieve reverse pupillary block. Anterior segment optical coherence tomography (AS-OCT) showed reversal of iris concavity after laser iridotomy.

A Severe Case of Pigmentary Glaucoma in a Child With a Family History of Pigment Dispersion Syndrome

2016 ◽  
Vol 25 (8) ◽  
pp. e745-e747 ◽  
Author(s):  
Vittoria Aragno ◽  
Pierre Zeboulon ◽  
Christophe Baudouin ◽  
Antoine Labbé
Keyword(s):  
Family History ◽  
Severe Case ◽  
Pigment Dispersion ◽  
Pigmentary Glaucoma ◽  
Pigment Dispersion Syndrome ◽  
History Of

scholarly journals A 10-Year Follow-up to Determine the Effect of YAG Laser Iridotomy on the Natural History of Pigment Dispersion Syndrome

2014 ◽  
Vol 132 (12) ◽  
pp. 1433 ◽  
Author(s):  
Stefano A. Gandolfi ◽  
Nicola Ungaro ◽  
Maria Grazia Tardini ◽  
Stella Ghirardini ◽  
Arturo Carta ◽  
...  
Keyword(s):  
Natural History ◽  
Pigment Dispersion ◽  
Yag Laser ◽  
Laser Iridotomy ◽  
Pigment Dispersion Syndrome ◽  
History Of

scholarly journals Use of automatic refractometer infrared images to screen pigment dispersion syndrome: a cross-sectional observational study from a preliminary hypothesis

2020 ◽  
Vol 1 (1) ◽  
pp. 25-28
Author(s):  
Paolo Brusini ◽  
Veronica Papa
Keyword(s):  
Observational Study ◽  
Pigment Epithelium ◽  
Anterior Segment ◽  
Pigment Dispersion ◽  
Pigmentary Glaucoma ◽  
Infrared Images ◽  
Cross Sectional ◽  
Pigment Dispersion Syndrome ◽  
Automatic Refractometer ◽  
Iris Pigment Epithelium

Background: This study was performed to evaluate the use of anterior segment images, obtained with an automatic refractometer, to identify early defects of the iris pigment epithelium in patients with pigment dispersion syndrome (PDS) or pigmentary glaucoma (PG) without observable alterations at the slit lamp. Methods: In this cross-sectional observational study, carried out from January 2018 to December 2019, in Policlinico Citta di Udine Health Center, Udine, Italy, we observed anterior segment infrared images of 1700 subjects who were undergoing routine ophthalmological examination using an automatic refractometer. We selected infrared images of subjects who fulfilled the inclusion and exclusion criteria and looked for a focal defect in the iris pigment epithelium. Results: Twenty patients with focal iris pigment epithelial defect were identified and none of them showed evident signs of PDS. After the necessary explanations, they agreed to have further examinations to verify the possibility of PDS. An in-depth evaluation of ocular structures, including gonioscopy, demonstrated the presence of PDS in all subjects with iris defects. Conclusions: The use of infrared images obtained by an automatic refractometer could provide early and easy identification of PDS in crowded ophthalmology clinics or mass screening programs; yet, more well-designed studies are necessary to confirm these preliminary findings and prove this proposed screening tool.

scholarly journals Implantation of a trifocal toric intraocular lens to a patient with pigment dispersion syndrome

2019 ◽  
Vol 100 (3) ◽  
pp. 495-499
Author(s):  
R F Akhmetshin ◽  
M R Gilyazev ◽  
A T Galeeva ◽  
S N Bulgar
Keyword(s):  
Intraocular Pressure ◽  
Intraocular Lens ◽  
Anterior Segment ◽  
Ultrasound Biomicroscopy ◽  
Pigment Dispersion ◽  
Toric Intraocular Lens ◽  
Lens Extraction ◽  
Pigment Dispersion Syndrome ◽  
Myopic Astigmatism ◽  
Peripheral Iridotomy

Aim. To present a clinical case of treatment of pigment dispersion syndrome by clear lens extraction and implantation of a toric intraocular lens in a patient with myopic astigmatism. Methods. A 33-year-old patient with a diagnosis of moderate myopia, complex mild myopic astigmatism, pigment dispersion syndrome of both eyes. Results. The first stage was laser peripheral iridotomy of both eyes. On follow-up pathological irido-zonular contact and increases intraocular pressure by 2 mm persisted. The second stage included clear lens extraction and implantation of a toric multifocal intraocular lens to both eyes. In 2 months, distance and near visual acuity was 1.0, intraocular pressure was normal, no pathological irido-zonular contact was observed according to the ultrasound biomicroscopy. Conclusion. Implantation of an intraocular lens in patients with myopia and pigment dispersion syndrome is both a method of preventing pigment glaucoma and myopia correction; patients with pigment dispersion syndrome after peripheral iridotomy should monitor the state of the anterior segment of the eye and the effectiveness of the treatment by ultrasound biomicroscopy.

Sign in / Sign up

Export Citation Format

Share Document