scholarly journals Retraction Note to: Vitamin A deficiency and sleep disturbances related to autism symptoms in children with autism spectrum disorder: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jing Wen ◽  
Ting Yang ◽  
Jiang Zhu ◽  
Min Guo ◽  
Xi Lai ◽  
...  

This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12887-021-03000-8.

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jing Wen ◽  
Ting Yang ◽  
Jiang Zhu ◽  
Min Guo ◽  
Xi Lai ◽  
...  

Abstract Background Vitamin A deficiency (VAD) and sleep disturbances have been reported in children with autism spectrum disorder (ASD). The influence of vitamin A (VA) levels on sleep regulation and sleep disturbances in ASD has garnered concern. The present study aimed to characterize the association of VA levels with sleep disturbances in children with ASD. Methods This cross-sectional study compared children with ASD (n = 856) to typically developing children (TDC; n = 316). We used the Children’s Sleep Habits Questionnaire to assess sleep disturbances, Childhood Autism Rating Scale to evaluate the severity of autism symptoms, and Autism Behavior Checklist and Social Responsiveness Scale to assess autism behaviors. Serum VA levels were estimated using high-performance liquid chromatography. Multivariable linear regression and two-way analysis of variance were performed to investigate if VAD was related to sleep disturbances in children with ASD. Results Children with ASD had lower serum VA levels and a higher prevalence of sleep disturbances than TDC did. The incidence of VAD in ASD children with sleep disturbances was higher, and the symptoms more severe than those without sleep disturbances and TDC. Interestingly, the interaction between VAD and sleep disturbances was associated with the severity of autism symptoms. Conclusion VAD and sleep disturbances are associated with the core symptoms of ASD in children. Regular monitoring of sleep and VA levels may be beneficial for children with ASD. Trial registration Chinese Clinical Trial Registry, registration number: ChiCTR-ROC-14005442, registration date: December 9th 2014.


2020 ◽  
Author(s):  
Jing Wen ◽  
Ting Yang ◽  
Jiang Zhu ◽  
Min Guo ◽  
Xi Lai ◽  
...  

Abstract Background: Vitamin A deficiency (VAD) and sleep disturbances have been reported in children with autism spectrum disorder (ASD). The influence of vitamin A (VA) on sleep regulation and sleep disturbances in ASD has garnered increased attention. This study aims to characterize the effect of VA levels and sleep disturbances on children with ASD.Methods: This cross-sectional study compared children with ASD (n=856) to typically developing children (TDC; n=316). The Children’s Sleep Habits Questionnaire assessed sleep disturbances, Childhood Autism Rating Scale evaluated the severity of autism symptoms, and Autism Behavior Checklist and Social Responsiveness Scale assessed autism behaviors. VA levels in blood samples were measured using high-performance liquid chromatography. Multivariable linear regression and two-way ANOVAs were performed to investigate the effect of VAD and sleep disturbances in children with ASD.Results: Children with ASD had lower serum VA levels and a higher prevalence of sleep disturbances than TDC. VAD and sleep disturbances in children with ASD corresponded to the severity of autism symptoms. Importantly, VA levels were negatively correlated with sleep disturbances among children with ASD, and the interaction of VAD and sleep disturbances were related to the severity of autism symptoms.Conclusion: VAD and sleep disturbances exacerbated autism symptoms in children with ASD, providing a novel target for treatment.Trial registration: Chinese Clinical Trial Registry, registration number: ChiCTR-ROC-14005442


Author(s):  
Usman Baig ◽  
Syed Muslim Mehdi ◽  
Hafiz Muhammad Imtiaz Afzal ◽  
Admin

Abstract Objective: To assess the frequency of insomnia and other sleep disturbances among children with autism spectrum disorder. Methods: Sleep disturbance scale for children was used in this descriptive cross-sectional study and the parents were asked to fill out the questionnaire along with the consent form. Initial sample size was 97, out of which 93 were included in study. The research was approved by institutional ethics committee of Sharif medical and Dental College. Results: This study showed that 37 (39.8%) children had at least one type of the sleeping disorder. Most common type were insomnia 24 (25.8%) and sleep-awake transition disorders 15 (16.1%), less common were disorders of arousal 10 (10.8%), disorders of excessive somnolence 7 (7.5%), sleep hyperhidrosis 5 (5.4%) and sleep breathing disorders 4 (4.3%). Conclusion: Nearly forty percent of children with autism spectrum disorder suffer from sleep disorders, among which the most frequent was insomnia. Keywords: Autism spectrum disorder, insomnia, sleep disorders, children


BMJ Open ◽  
2014 ◽  
Vol 4 (6) ◽  
pp. e004786-e004786 ◽  
Author(s):  
L. Burgoyne ◽  
L. Dowling ◽  
A. Fitzgerald ◽  
M. Connolly ◽  
J. P Browne ◽  
...  

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Milena Pereira Pondé ◽  
Sabrina Calmon Oliveira ◽  
Saulo Leal Merelles ◽  
Gustavo Marcelino Siquara

Parents of children with autism spectrum disorder may be more likely to have a mental disorder, both due to genetic and environmental reasons. A cross-sectional study involving 161 children, 161 mothers and 108 fathers. Diagnosis followed the criteria established in DSM–5. Symptom severity was evaluated using the Childhood Autism Rating Scale. The Factorial Personality Inventory served to evaluate parents’ personality traits.  Several correlations were found between mothers and fathers personality traits and children symptoms. In both parents, personality traits associated with greater intransigence/less flexibility and fewer social skills were those associated with more severe autism symptoms in the children.


2017 ◽  
Vol 74 ◽  
pp. 62-67 ◽  
Author(s):  
Ravindranath Aathira ◽  
Sheffali Gulati ◽  
Manjari Tripathi ◽  
Garima Shukla ◽  
Biswaroop Chakrabarty ◽  
...  

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