scholarly journals Temporal changes in breast cancer screening coverage provided under the Brazilian National Health Service between 2008 and 2017

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Danielle Cristina Netto Rodrigues ◽  
Ruffo Freitas-Junior ◽  
Rosemar Macedo Sousa Rahal ◽  
Rosangela da Silveira Corrêa ◽  
Pollyana Alves Gouveia ◽  
...  
2021 ◽  
pp. 096914132110596
Author(s):  
David Carr ◽  
David Kent ◽  
H. Gilbert Welch

A randomized trial of the GRAIL GalleriTM multi-cancer screening test is being planned for the National Health Service in England, and will have 140,000 healthy participants aged 50–79: 70,000 exposed to screening and 70,000 unexposed. The test reportedly detects 50 different cancers and is expected to reduce all-cancer mortality by approximately 25%. Given this effect size—and that cancer deaths constitute a large fraction of all deaths—the trial is sufficiently large to test the effect on all-cause mortality. Because most patients believe cancer screening “saves lives”, the GRAIL/National Health Service collaboration could set the evaluation standard for multi-cancer screening.


BMJ Open ◽  
2018 ◽  
Vol 8 (9) ◽  
pp. e021653 ◽  
Author(s):  
Alessio Petrelli ◽  
Paolo Giorgi Rossi ◽  
Lisa Francovich ◽  
Barbara Giordani ◽  
Anteo Di Napoli ◽  
...  

ObjectiveThe Italian National Health Service instituted cervical and breast cancer screening programmes in 1999; the local health authorities have a mandate to implement these screening programmes by inviting all women aged 25–64 years for a Pap test every 3 years (or for an Human Papilloma Virus (HPV) test every 5 years) and women aged 50–69 years for a mammography every 2 years. However, the implementation of screening programmes throughout the country is still incomplete. This study aims to: (1) describe cervical and breast cancer screening uptake and (2) evaluate geographical and individual socioeconomic difference in screening uptake.MethodsData both from the Italian National Health Interview Survey (NHIS) conducted by the National Institute of Statistics in 2012–2013 and from the Italian National Centre for Screening Monitoring (INCSM) were used. The NHIS interviewed a national representative random sample of 32 831 women aged 25–64 years and of 16 459 women aged 50–69 years. Logistic multilevel models were used to estimate the effect of socioeconomic variables and behavioural factors (level 1) on screening uptake. Data on screening invitation coverage at the regional level, taken from INCSM, were used as ecological (level 2) covariates.ResultsTotal 3-year Pap test and 2-year mammography uptake were 62.1% and 56.4%, respectively; screening programmes accounted for 1/3 and 1/2 of total test uptake, respectively. Strong geographical differences were observed. Uptake was associated with high educational levels, healthy behaviours, being a former smoker and being Italian versus foreign national. Differences in uptake between Italian regions were mostly explained by the invitation coverage to screening programmes.ConclusionsThe uptake of both screening programmes in Italy is still under acceptable levels. Screening programme implementation has the potential to reduce the health inequalities gap between regions but only if uptake increases.


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