scholarly journals Pilot study of a two-arm non-randomized controlled cluster trial of a psychosocial intervention to improve late life depression in socioeconomically deprived areas of São Paulo, Brazil (PROACTIVE): feasibility study of a psychosocial intervention for late life depression in São Paulo

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Marcia Scazufca ◽  
Maria Clara P. de Paula Couto ◽  
Maiara Garcia Henrique ◽  
Ana Vilela Mendes ◽  
Alicia Matijasevich ◽  
...  
Keyword(s):  
Pilot Study ◽  
Feasibility Study ◽  
Psychosocial Intervention ◽  
Late Life ◽  
Sao Paulo ◽  
São Paulo ◽  
Cluster Trial ◽  
Late Life Depression ◽  
Randomized Controlled ◽  
Deprived Areas

scholarly journals Use of doxycycline for leptospirosis after high-risk exposure in São Paulo, Brazil

1998 ◽  
Vol 40 (1) ◽  
pp. 59-61 ◽  
Author(s):  
Claudio R. GONSALEZ ◽  
Jorge CASSEB ◽  
Francisco G. V. MONTEIRO ◽  
João B. PAULA-NETO ◽  
Rufino B. FERNANDEZ ◽  
...  
Keyword(s):  
Pilot Study ◽  
Treated Group ◽  
Sao Paulo ◽  
Risk Exposure ◽  
São Paulo ◽  
High Exposure ◽  
Igm Antibodies ◽  
Igm Antibody ◽  
Double Blinded ◽  
Number Of Individuals

A clinical trial pilot study, double-blinded, randomized, and controlled with a placebo to assess the effectiveness of oral doxycycline (200 mg, single dose) in preventing leptospirosis after high exposure to potentially contamined water was performed in São Paulo, SP, Brazil. Confirmed cases were defined as those with leptospira IgM antibody and symptoms; asymptomatic cases were those presenting with IgM antibodies but no symptoms; and suspected cases were individuals with symptoms but no IgM antibody. Forty subjects were given doxycycline and 42 were given placebo. In the drug-treated group there were 2 confirmed cases, 11 asymptomatic cases, and 6 suspected cases. In the placebo group there were 5 confirmed, 6 symptomatic, and 5 suspected cases. Even though we found a protective association of doxycycline for confirmed leptospirosis cases (RR = 2.3) and seroconversion only (RR = 2.0), the association was not statistically significant because of the small number of individuals enrolled in this pilot study. We observed that the 22% of the volunteers already had IgM antibodies to leptospirosis at the first sampling. Finally, the attack rate to confirmed, asymptomatic, and suspected cases of Leptospirosis was 8.5%, 22%, and 13%, respectively, in this population.

A Pilot Study: The Impact of Transdermal Nicotine on Late Life Depression

2018 ◽  
Vol 26 (3) ◽  
pp. S87
Author(s):  
Jason A. Gandelman ◽  
Hakmook Kang ◽  
Warren D. Taylor
Keyword(s):  
Pilot Study ◽  
Late Life ◽  
Late Life Depression ◽  
Transdermal Nicotine ◽  
The Impact

scholarly journals Aplicabilidade da classificação das intervenções e atividades de nutrição clínica em unidade hospitalar: estudo piloto/ Applicability of the clinical nutrition interventions classification and activities in a hospital unit: pilot study

2017 ◽  
Vol 16 (4) ◽  
Author(s):  
Clotilde Oliveira ◽  
Raquel Gaidzinski
Keyword(s):  
Pilot Study ◽  
Sao Paulo ◽  
Clinical Nutrition ◽  
São Paulo ◽  
Nutrition Interventions ◽  
Hospital Unit

Este estudo teve como objetivo avaliar a viabilidade do uso de uma classificação de intervenções/atividades executadas por nutricionistas no ambiente hospitalar e descrever o processo de trabalho destes profissionais. Pesquisa transversal, descritiva, observacional, realizada em um hospital público, no município de São Paulo. Participaram duas nutricionistas da unidade de internação cirúrgica. O instrumento aplicado contemplava o elenco de intervenções/atividades desenvolvidas pelos nutricionistas no Brasil. O tempo despendido pelos nutricionistas foi obtido pela observação direta e contínua das intervenções/atividades realizadas durante jornada de trabalho, por meio da técnica de tempo e movimento. Para análise dos dados, aplicou-se a estatística descritiva. O instrumento testado permitiu identificar todas as intervenções/atividades realizadas pelos nutricionistas, sem necessidade de alteração. Foram observadas 68,8% (22) intervenções/atividades.  O tempo total observado correspondeu 1920 minutos. As nutricionistas despenderam a maior parte do tempo de trabalho em intervenções de cuidados diretos e indiretos (1406 minutos; 55,9%), espera (358 minutos; 18,6%), atividades pessoais (206,4 minutos; 10,8%) e deslocamento (205,4 minutos; 10,7%). O uso desse instrumento mostrou potencial para ser aplicado em unidades hospitalares brasileiras e forneceu dados preliminares sobre a prática profissional dos nutricionistas observados.

Salivary antibody detection in epidemiological surveys: a pilot study after a mass vaccination campaign against rubella in São Paulo, Brazil

1995 ◽  
Vol 89 (1) ◽  
pp. 115-118 ◽  
Author(s):  
Raymundo Scares de Azevedo Neto ◽  
Alison Richards ◽  
David James Nokes ◽  
Ana Silvia Barreiros Silveira ◽  
Bernard John Cohen ◽  
...  
Keyword(s):  
Pilot Study ◽  
Vaccination Campaign ◽  
Sao Paulo ◽  
Mass Vaccination ◽  
Antibody Detection ◽  
São Paulo ◽  
Mass Vaccination Campaign ◽  
Epidemiological Surveys

Collaborative care for primary care treatment of late‐life depression in Singapore: Randomized controlled trial

2020 ◽  
Vol 35 (10) ◽  
pp. 1171-1180
Author(s):  
Tze Pin Ng ◽  
Ma S. Z. Nyunt ◽  
Liang Feng ◽  
Rajeev Kumar ◽  
Calvin S. L. Fones ◽  
...  
Keyword(s):  
Primary Care ◽  
Randomized Controlled Trial ◽  
Collaborative Care ◽  
Controlled Trial ◽  
Late Life ◽  
Late Life Depression ◽  
Randomized Controlled ◽  
Care Treatment

Feasibility study of MOS in Brazil using roll-on/roll-off vessels between Manaus and São Paulo

2016 ◽  
pp. 105-115
Author(s):  
R Pelícia ◽  
M Peli ◽  
M da Silva ◽  
R Botter ◽  
N Pereira
Keyword(s):  
Feasibility Study ◽  
Sao Paulo ◽  
São Paulo

scholarly journals Behavioural activation by mental health nurses for late-life depression in primary care: a randomized controlled trial

2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Noortje Janssen ◽  
Marcus J.H. Huibers ◽  
Peter Lucassen ◽  
Richard Oude Voshaar ◽  
Harm van Marwijk ◽  
...  
Keyword(s):  
Mental Health ◽  
Primary Care ◽  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Late Life ◽  
Behavioural Activation ◽  
Late Life Depression ◽  
Mental Health Nurses ◽  
Randomized Controlled

scholarly journals Sahaj Samadhi meditation vs a Health Enhancement Program in improving late-life depression severity and executive function: study protocol for a two-site, randomized controlled trial

Trials ◽  
2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Stephen Benjamin Peckham ◽  
Emily Ionson ◽  
Marouane Nassim ◽  
Kevin Ojha ◽  
Lena Palaniyappan ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Executive Functioning ◽  
Controlled Trial ◽  
Late Life ◽  
Care Providers ◽  
Depression Severity ◽  
Late Life Depression ◽  
Randomized Controlled ◽  
Increased Risk ◽  
Augmentation Strategy

Abstract Background Recent estimates suggest an 11% prevalence of current late-life depression (LLD) and a lifetime prevalence of 16–20%. LLD leads to cognitive disturbance as well as a nearly two to three times increased risk of dementia. We conducted a recent randomized controlled trial (RCT) which demonstrated that Sahaj Samadhi meditation (SSM), an easy-to-implement, meditation-based augmentation strategy, led to higher rates of symptom remission when compared to treatment as usual (40.0 vs 16.3%; odds ratio, 3.36; 95% CI 1.06–10.64; p = 0.040). Here we present a protocol describing a two-site, blinded, RCT, comparing an SSM arm to an active-control arm – a Health Enhancement Program (HEP) intervention – in their ability to reduce depressive symptoms and improve executive functioning, among several other exploratory outcomes. Methods/design One hundred and ninety-two (n = 192) participants with LLD will be recruited at two sites (London, ON, Canada, and Montreal, QC, Canada). Participants will undergo stratified randomization with regards to site and the presence of treatment-resistant-LLD (TR-LLD) or not, to either SSM or HEP. We will assess change in (1) depression severity using the Hamilton Depression Rating Scale (HAM-D), (2) executive functioning, and (3) other exploratory physiological and mood-based measures, at baseline (0 weeks), post intervention (12 weeks), and 26 weeks after baseline. Raters, clinicians, and care providers will be blinded to group allocation while participants will be blinded to the study hypotheses. Discussion This study should more definitively assess whether SSM can be used as an augmentation strategy in routine clinical care for patients suffering from LLD and TR-LLD. If the effects of SSM are significantly better than HEP, it will offer support for the routine use of this intervention to manage LLD/TR-LLD and comorbid declines in executive dysfunction. The results of this study could also inform whether SSM can improve/prevent cognitive decline in LLD. Trial registration ClinicalTrials.gov, ID: NCT03564041. Registered on 20 June 2018.

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