scholarly journals Free radical scavenging, α-glucosidase inhibitory and lipase inhibitory activities of eighteen Sudanese medicinal plants

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Sara Mustafa Idris Elbashir ◽  
Hari Prasad Devkota ◽  
Mikiyo Wada ◽  
Naoki Kishimoto ◽  
Masataka Moriuchi ◽  
...  
Keyword(s):  
Free Radical ◽  
Medicinal Plants ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Inhibitory Activities ◽  
Sudanese Medicinal Plants

scholarly journals Phytochemical Screening, Free Radical Scavenging and α-Amylase Inhibitory Activities of Selected Medicinal Plants from Western Nepal

Medicines ◽  
2019 ◽  
Vol 6 (2) ◽  
pp. 70 ◽  
Author(s):  
Kusum Sai ◽  
Rashmi Thapa ◽  
Hari Prasad Devkota ◽  
Khem Raj Joshi
Keyword(s):  
Free Radical ◽  
Medicinal Plants ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activity ◽  
Total Phenolic ◽  
Scavenging Activity ◽  
Phytochemical Screening ◽  
Inhibitory Activities

Background: More than 700 plants are reported to be used for medicinal purposes in Nepal; however, many of them are not studied for their scientific evidences. The aims of the present study were the estimation of the total phenolic and flavonoid contents, and the evaluation of the free radical scavenging and α-amylase inhibitory activities of five selected medicinal plants from western Nepal: Aeschynanthus parviflorus Wall. (Gesneriaceae), Buddleja asiatica Lour. (Loganiaceae), Carica papaya L. (Caricaceae), Drepanostachyum falcatum (Nees) Keng f. (Gramineae) and Spondias pinnata (L. f.) Kurz (Anacardiaceae). Methods: The total phenolic content (TPC) and total flavonoid content (TFC) were measured using Folin-Ciocalteu’s phenol reagent and aluminium chloride methods, respectively. A 1,1–diphenyl–2–picrylhydrazyl (DPPH) free radical scavenging assay was used to evaluate the free radical scavenging activity and an α-amylase inhibitory assay was carried out to determine the in vitro antidiabetic activity. Results: The phytochemical screening of five hydroalcoholic plant extracts revealed the presence of various secondary metabolites, including alkaloids, flavonoids, reducing sugars, saponins, terpenoids and tannins. The amounts of total phenolics and flavonoids were found to be the highest in B. asiatica leaf extract, which also showed the most potent free radical scavenging activity. Extract of C. papaya fruits showed the highest α-amylase inhibitory activity, whereas the extracts of B. asiatica leaves and S. pinnata leaves exhibited moderate activity. Conclusions: Some of the medicinal plants selected in this study showed high TPC and TFC values and potent bioactivities. These results may provide the scientific evidences of the traditional uses of these plants. However, further detailed studies on bioactive compounds isolation and identification and evaluation of in vivo pharmacological activities should be performed in future.

The Assessment of the Free Radical Scavenging Activity and Flavonoid Contents of Selected Medicinal Plants of Mizoram

2020 ◽  
Vol 15 (1) ◽  
pp. 34-43
Author(s):  
Alex Zohmachhuana ◽  
Malsawmdawngliana Malsawmdawngliana M ◽  
Lalrinzuali K Lalrinzuali ◽  
Lalnunmawia F Lalnunmawia ◽  
Vabeiryureilai M Vabeiryureilai ◽  
...  
Keyword(s):  
Free Radical ◽  
Medicinal Plants ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activity ◽  
Scavenging Activity

scholarly journals Constituents of the Stem of Nauclea orientalis

2015 ◽  
Vol 10 (11) ◽  
pp. 1934578X1501001 ◽  
Author(s):  
Phan Thi Anh Dao ◽  
Tran Le Quan ◽  
Nguyen Thi Thanh Mai
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Free Radical ◽  
Spectroscopic Data ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Propanoic Acid ◽  
Coumaric Acid ◽  
Aloe Emodin ◽  
Inhibitory Activities

A new α-pinene derivative (1) was isolated from the stem of Nauclea orientalis (L.) L. (Rubiaceae), together with twelve known compounds, including four terpenoids, loganetin (2), loganin (3), sweroside (4), grandifloroside (5), four simple phenols, methyl protocatechuate (6), trans- p-coumaric acid (7), 3-(2,4-dihydroxylphenyl)propanoic acid (8), methyl 3-(2,4-dihydroxylphenyl)propanoate (9), two coumarin glucosides, skimmin (10), adicardin (11), an anthraquinone, aloe emodin (12), and a lignan, (+)-pinoresinol (13). Their structures were elucidated on the basis of spectroscopic data. All compounds were tested for DPPH free radical scavenging and lipid peroxidation inhibitory activities. Among them, compounds 5 and 6 displayed strong antioxidant activity with IC50 values of 6.6 and 67.9 μM, 12.4 and 813.0 μM, respectively.

scholarly journals ANTIFUNGAL, AFLATOXIN INHIBITORY AND FREE RADICAL-SCAVENGING ACTIVITIES OF SOME MEDICINAL PLANTS EXTRACTS

2012 ◽  
Vol 35 (3) ◽  
pp. 182-189 ◽  
Author(s):  
RAVINDRA SHUKLA ◽  
PRIYANKA SINGH ◽  
BHANU PRAKASH ◽  
ANURADHA ◽  
N.K. DUBEY
Keyword(s):  
Free Radical ◽  
Medicinal Plants ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activities
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