scholarly journals Porcine vs bovine surfactant therapy for preterm neonates with RDS: systematic review with biological plausibility and pragmatic meta-analysis of respiratory outcomes

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Ascanio Tridente ◽  
Lucia De Martino ◽  
Daniele De Luca
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Surfactant Therapy ◽  
Preterm Neonates ◽  
Biological Plausibility ◽  
Respiratory Outcomes

Surfactant therapy in lung transplantation: A systematic review and meta-analysis

2021 ◽  
pp. 100637
Author(s):  
Aadil Ali ◽  
Tommaso Pettenuzzo ◽  
Khaled Ramadan ◽  
Ashley Farrell MLIS ◽  
Matteo Di Nardo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Lung Transplantation ◽  
Meta Analysis ◽  
Surfactant Therapy

Efficacy of noninvasive respiratory support modes as postextubation respiratory support in preterm neonates: A systematic review and network meta‐analysis

2020 ◽  
Vol 55 (11) ◽  
pp. 2924-2939
Author(s):  
Viraraghavan Vadakkencherry Ramaswamy ◽  
Tapas Bandyopadhyay ◽  
Debasish Nanda ◽  
Prathik Bandiya ◽  
Kiran More ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Respiratory Support ◽  
Preterm Neonates

scholarly journals Awake prone positioning in non-intubated patients for the management of hypoxemia in COVID-19: A systematic review and meta-analysis

2021 ◽  
Vol 91 (2) ◽  
Author(s):  
Sryma PB ◽  
Saurabh Mittal ◽  
Karan Madan ◽  
Anant Mohan ◽  
Pawan Tiwari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Mechanical Ventilation ◽  
Therapeutic Strategy ◽  
Meta Analysis ◽  
Prone Positioning ◽  
Limited Evidence ◽  
Prospective Trials ◽  
Respiratory Outcomes ◽  
The Impact

Coronavirus disease-2019 (COVID-19) may lead to hypoxemia, requiring intensive care in many patients. Awake prone positioning (PP) is reported to improve oxygenation and is a relatively safe modality. We performed a systematic review of the literature to evaluate the available evidence and performed meta-analysis of the effect of awake PP in non-intubated patients on improvement in oxygenation and reducing the need for intubation. We searched the PubMed and EMBASE databases to identify studies using awake PP as a therapeutic strategy in the management of COVID-19. Studies were included if they reported respiratory outcomes and included five or more subjects. The quality of individual studies was assessed by the Qualsyst tool. A meta-analysis was performed to estimate the proportion of patients requiring intubation. The degree of improvement in oxygenation parameters (PaO2: FiO2 or PaO2 or SpO2) was also calculated. Sixteen studies (seven prospective trials, three before-after studies, six retrospective series) were selected for review. The pooled proportion of patients who required mechanical ventilation was 0.25 (95% confidence interval (CI) 0.16-0.34). There was a significant improvement in PaO2: FiO2 ratio, PaO2, and SpO2 during awake PP. To conclude, there is limited evidence to support the efficacy of awake PP for the management of hypoxemia in COVID-19. Further RCTs are required to study the impact of awake PP on key parameters like avoidance of mechanical ventilation, length of stay, and mortality.

scholarly journals Respiratory Outcomes in Patients Following COVID-19-Related Hospitalization: A Meta-Analysis

2021 ◽  
Vol 8 ◽  
Author(s):  
Tao Guo ◽  
Fangfang Jiang ◽  
Yufei Liu ◽  
Yunpeng Zhao ◽  
Yiran Li ◽  
...  
Keyword(s):  
Systematic Review ◽  
Carbon Monoxide ◽  
Vital Capacity ◽  
Meta Analysis ◽  
Diffusing Capacity ◽  
Post Discharge ◽  
Lung Diffusion ◽  
High Prevalence ◽  
Respiratory Outcomes

Background: To determine the respiratory outcomes in patients following COVID-19-related hospitalization.Methods: Systematic review and meta-analysis of the literature.Results: Forced vital capacity (FVC, % of predicted): 0–3 months post discharge: 96.1, 95% CI [82.1–110.0]; 3–6 months post discharge: 99.9, 95% CI [84.8, 115.0]; >6 months post discharge: 97.4, 95% CI [76.8–118.0]. Diffusing capacity of the lungs for carbon monoxide (DLCO, % of predicted): 0–3 months post discharge: 83.9, 95% CI [68.9–98.9]; 3–6 months post discharge: 91.2, 95% CI [74.8–107.7]; >6 months post discharge: 97.3, 95% CI [76.7–117.9]. Percentage of patients with FVC less than 80% of predicted: 0–3 months post discharge: 10%, 95% CI [6–14%]; 3–6 months post discharge: 10%, 95% CI [2–18%]; >6 months post discharge: 13%, 95% CI [8–18%]. Percentage of patients with DLCO less than 80% of predicted: 0–3 months post discharge: 48%, 95% CI [41–56%]; 3–6 months post discharge: 33%, 95% CI [23–44%]; >6 months post discharge: 43%, 95% CI [22–65%].Conclusion: The meta-analysis confirms a high prevalence of persistent lung diffusion impairment in patients following COVID-19-related hospitalization. Routine respiratory follow-up is thus strongly recommended.

scholarly journals Meconium Evacuation for Facilitating Feed Tolerance in Preterm Neonates: A Systematic Review and Meta-Analysis

Neonatology ◽  
2016 ◽  
Vol 110 (1) ◽  
pp. 55-65 ◽  
Author(s):  
Mangesh Deshmukh ◽  
Hari Balasubramanian ◽  
Sanjay Patole
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Preterm Neonates

Systematic Review and Meta-Analysis of treatment of Palpable Undescended Testis

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Hassan Abdel Monem Abdallah ◽  
Mohamed Soliman El-Debeiky ◽  
Amr Abdel Raouf Abdel Nasser
Keyword(s):  
Systematic Review ◽  
Success Rate ◽  
Hormonal Therapy ◽  
Undescended Testis ◽  
Meta Analysis ◽  
Good Evidence ◽  
Preterm Neonates ◽  
Case Control Studies ◽  
Retrospective Case ◽  
Delay Of Treatment

Abstract Background Undescended testis is the most common endocrinological disease in the male newborn period. Incidence varies between 1.0% and 4.6% in full-term neonates, with rates as high as 45% in preterm neonates. Failure or delay of treatment can result in reduced fertility and/or increased testicular cancer risk in adulthood. Aim and objectives : To establish, through the available literature, which is the best technique, either hormonal therapy or surgical orchiopexy for treatment of palpable undescended testis through systematic review and meta-analysis. Subjects and methods : The review considered case-control studies, case report studies, and retrospective case follow-up evaluating the effectiveness or efficacy of a certain technique of treatment of palpable undescended testicles over other techniques either hormonal therapy and surgical orchiopexy according to age of the patient, This review considered all studies that involve infants with palpable undescended testicles, Search strategy is designed to include both manual and electronic data available. Electronic searches involved searching databases of PubMed (from Jan. 1987 till July 2017), EMbase, CINAHL and Cochrane database. Results The overall success rate of primary orchiopexy is 96.4% and the overall success rate for 2- stage FS is 86%. Conclusion There is good evidence for early placement of undescended testes in the scrotal position to prevent potential impairment of fertility and reduce the risk of testicular malignancy.

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