scholarly journals Age and gender-specific distribution of metabolic syndrome components in East China: role of hypertriglyceridemia in the SPECT-China study

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Boren Jiang ◽  
Yanjun Zheng ◽  
Yingchao Chen ◽  
Yi Chen ◽  
Qin Li ◽  
...  
2014 ◽  
Vol 13s1 ◽  
pp. CIN.S13893 ◽  
Author(s):  
Yang Chen ◽  
Rong Xu

Cancer comorbidities often reflect the complex pathogenesis of cancers and provide valuable clues to discover the underlying genetic mechanisms of cancers. In this study, we systematically mine and analyze cancer-specific comorbidity from the FDA Adverse Event Reporting System. We stratified 3,354,043 patients based on age and gender, and developed a network-based approach to extract comorbidity patterns from each patient group. We compared the comorbidity patterns among different patient groups and investigated the effect of age and gender on cancer comorbidity patterns. The results demonstrated that the comorbidity relationships between cancers and non-cancer diseases largely depend on age and gender. A few exceptions are depression, anxiety, and metabolic syndrome, whose comorbidity relationships with cancers are relatively stable among all patients. Literature evidences demonstrate that these stable cancer comorbidities reflect the pathogenesis of cancers. We applied our comorbidity mining approach on colorectal cancer and detected its comorbid associations with metabolic syndrome components, diabetes, and osteoporosis. Our results not only confirmed known cancer comorbidities but also generated novel hypotheses, which can illuminate the common pathophysiology between cancers and their co-occurring diseases.


2016 ◽  
Vol 41 (2) ◽  
Author(s):  
Elke Loichinger ◽  
Vegard Skirbekk

Within this analysis of demographic and economic dependency ratios for 45 countries around the world, we reiterate the importance of age- and gender-specific employment levels as well as their determinants when discussing the economic challenges associated with population ageing. Building upon existing research on economic dependency, we portray and discuss cohort variation in employment and its possible effect on the challenges of population ageing, focusing on the implications of high youth unemployment, the role of changes in female employment and the evolution of retirement patterns across cohorts. The insights from our analysis reaffirm findings elsewhere that younger populations may not be as well off in the light of demographic change as an analysis of their demographic structure alone would suggest and stress the importance of considering the cohort dimension of employment in this discussion.


Scientifica ◽  
2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Peter Schwandt ◽  
Thomas Bertsch ◽  
Evelyn Liepold ◽  
Gerda-Maria Haas

Because first graders are critical for excess weight gain, we assessed components of the metabolic syndrome (MetS) using the pediatric definition of the International Diabetes Federation (IDF). We compared four MetS components as defined by the IDF with age- and gender-specific components in 2228 first graders at the age of 6. The growth curves were derived from 22113 children and adolescents who participated in the PEP Family Heart Study. The aim was to determine in first graders precise values of waist circumference (WC), blood pressure (BP), triglycerides (TG), and HDL-Cholesterol (HDL-C) based on growth curves that were developed for a large German population of youths and to assess the prevalence in terms of both definitions at this critical age. The prevalence of high blood pressure for age was 13% compared with only 2% according to IDF. Because of this considerable divergence, we propose to define MetS components based on national growth curves.


2015 ◽  
Vol 40 (3) ◽  
pp. 521-530 ◽  
Author(s):  
Adeela Shahid ◽  
Sobia Rana ◽  
Saqib Mahmood ◽  
Shahid Saeed

2019 ◽  
Vol 32 (5) ◽  
pp. 429-438
Author(s):  
Chunming Ma ◽  
Qiang Lu ◽  
Rui Wang ◽  
Fuzai Yin

Abstract Metabolic syndrome (MS) is common among children and adolescents. Age- and gender-specific references or age-, gender- and height-specific references were used in pediatric MS definitions. More recently, an increasing number of studies documented that the ratio of waist circumference (WC) to height (WHtR) and blood pressure to height (BPHR) were easy anthropometric indexes for detection of obesity and hypertension in children and adolescents. For these reasons, height-corrected MS definition was proposed. WHtR and BPHR were used as alternatives to WC and BP in the definition of MS. In the present review, we discuss the possibility of the height-corrected MS definition for identifying MS in children.


2012 ◽  
Vol 76 (6) ◽  
pp. 802-809 ◽  
Author(s):  
Jun-Hua Yin ◽  
Zhen-Ya Song ◽  
Peng-Fei Shan ◽  
Jun Xu ◽  
Zhi-Min Ye ◽  
...  

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