scholarly journals Different signaling pathways involved in the anti-inflammatory effects of unfractionated heparin on lipopolysaccharide-stimulated human endothelial cells

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
Xu Li ◽  
Lu Li ◽  
Yuequan Shi ◽  
Sihan Yu ◽  
Xiaochun Ma
Author(s):  
Rougang Li ◽  
Arunachalam Chinnathambi ◽  
Sulaiman Ali Alharbi ◽  
Omar H. M. Shair ◽  
Vishnu Priya Veeraraghavan ◽  
...  

2013 ◽  
Vol 1833 (6) ◽  
pp. 1553-1561 ◽  
Author(s):  
Renata P. Guedes ◽  
Eduardo Rocha ◽  
Jerome Mahiou ◽  
Herwig P. Moll ◽  
Maria B. Arvelo ◽  
...  

Inflammation ◽  
2014 ◽  
Vol 38 (2) ◽  
pp. 784-799 ◽  
Author(s):  
Sae-Kwang Ku ◽  
Wei Zhou ◽  
Wonhwa Lee ◽  
Min-Su Han ◽  
MinKyun Na ◽  
...  

BMB Reports ◽  
2012 ◽  
Vol 45 (3) ◽  
pp. 200-205 ◽  
Author(s):  
Tae-Hoon Kim ◽  
Sae-Kwang Ku ◽  
In-Chul Lee ◽  
Jong-Sup Bae

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Huiyun Wang ◽  
Yangrong Xu ◽  
Mingzhu Luan ◽  
Fenglan Zhao ◽  
...  

: Oleanolic acid can inhibit edema and exhibit obvious inhibitory activity to inflammatory by activating of the pituitary-adrenal cortical system, inhibiting the synthesis or release of PGs, inhibiting endotoxin-mediated release of HMGB1 by endothelial cells or regulating MAPK, PI3K/Akt/NF-κB/ICAM-1/JAK/STAT signaling pathways, etc. In recent years, an increased number of interesting research work has been carried out on the anti-inflammatory activity and mechanisms of OA derivatives, such as acyloxyimino derivative, 3-acetylated derivatives, novel 3,5-disubstituted isoxazoles derivatives, acetate, ester derivatives and oximes derivatives. The review summaries and highlights the update advances on the anti-inflammatory activity and mechanism of OA and its derivatives.


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