scholarly journals Cost-effectiveness of antibiotic prophylaxis in elective cesarean section

2018 ◽  
Vol 16 (1) ◽  
Author(s):  
Markus H. Jansson ◽  
Yang Cao ◽  
Kerstin Nilsson ◽  
Per-Göran Larsson ◽  
Lars Hagberg
Keyword(s):  
Cost Effectiveness ◽  
Cesarean Section ◽  
Antibiotic Prophylaxis ◽  
Elective Cesarean Section ◽  
Elective Cesarean

scholarly journals Single dose of antibiotic prophylaxis in elective cesarean sections

2009 ◽  
Vol 62 (3-4) ◽  
pp. 101-106 ◽  
Author(s):  
Zorica Grujic ◽  
Ana Sabo ◽  
Ilija Grujic ◽  
Vesna Kopitovic ◽  
Maja Papovic
Keyword(s):  
Single Dose ◽  
Cesarean Section ◽  
Antibiotic Prophylaxis ◽  
Mode Of Delivery ◽  
Elective Cesarean Section ◽  
Cesarean Sections ◽  
Postoperative Infections ◽  
Dose Administration ◽  
Preoperative Administration ◽  
Elective Cesarean

Introduction. The aim of our study was to determine whether a single-dose preoperative administration of antibiotics was sufficient to prevent intra and postoperative infections in the parturients without a high risk of developing an infection, in whom the delivery was completed by cesarean section, as well as to answer whether the administered dose of antibiotics satisfied the requirements of therapeutic concentrations necessary to protect against infection in the period during the surgical procedure and during the first 6 postoperative hours. Material and methods. All investigated pregnant women were planned to have elective cesarean section as a mode of delivery. They were distributed in groups depending on the type (cephalexin, gentamycin and cephazolin) of antibiotic prophylaxis administered as a single dose. In all patients the clinical postoperative course was followed for possible infection. The concentrations of antibiotics were estimated immediately and 6h following the operation. The estimation of antibiotic concentrations was done by the method of liquid chromatography (for antibiotics belonging to the group of cephalosporins), i.e. RIA method for antibiotics from the group of aminoglycosides. Results and conclusion. The total number of infections in investigated groups was 5.18%. The measured mean concentrations of administered antibiotics following the operation and 6 h later were above MIC. This is a proof that the obtained antibiotic prophylaxis by a single dose administration of anbtibiotic is sufficient to prevent the invasion of pathogenic microorganisms from the skin.

scholarly journals Is It Necessary to Perform a Routine Antibiotic Prophylaxis before an Elective Surgery of Cesarean Section?

2021 ◽  
Vol 9 (B) ◽  
pp. 1-5
Author(s):  
Sergei Belyaev ◽  
Larysa Nazarenko ◽  
Liliya Dubrova ◽  
Olena Fedota
Keyword(s):  
Cesarean Section ◽  
Antibiotic Prophylaxis ◽  
Clinical Symptoms ◽  
Elective Surgery ◽  
Statistical Processing ◽  
Infectious Complications ◽  
World Health ◽  
Elective Cesarean Section ◽  
Post Operative Period ◽  
Elective Cesarean

INTRODUCTION: According to the data by World Health Organization, the broad and often insufficiently substantiated prescription of antibiotics, including for prophylactic purposes, has led to the growth of antibiotic-resistant microflora, which is a dangerous and intractable problem of modern medicine. Despite the undoubted benefits of antibiotics in the management of wound infection and endometritis after cesarean section, the routine prophylactic administration of antibacterial drugs can not only carry the risk of growth of resistant nosocomial microflora, but also have doubtful effects on the health of a newborn. PURPOSE OF THE STUDY: The purpose of the study was to justify the possibility of carrying out elective cesarean section operations without routine antibiotic prophylaxis. MATERIALS AND METHODS: An analysis of 333 cases of elective cesarean section operations carried out in the obstetric department in the period from 2017 to 2019 was performed. Routine antibiotic prophylaxis before surgery was not prescribed in 118 healthy patients with an uncomplicated history and a smooth course of the gestational process. The remaining 215 women received a single intravenous injection of 1 g of cefazolin sodium intraoperatively, after extraction of the fetus. A comparative analysis of the clinical groups was carried out according to the following criteria: vaginal microbiocenosis before surgical delivery, duration, and features of the operation, clinical blood count on days 1 and 5 of the post-operative period, condition of postoperative sutures, the presence of discharge from the wound, signs of infectious complications from the uterus or other organs, uterine involution rate, duration of hospital stay before and after surgery, follow-up history for 1 month after discharge from the maternity ward. The data obtained were subjected to statistical processing. RESULTS: We have found no significant differences in the course and number of complications in the postpartum period in the compared clinical groups. The statistically significant transient leukocytosis observed on the 1st day of the postoperative period in patients who did not undergo antibiotic prophylaxis before the surgery seems to be associated with a more pronounced adaptive reaction and was not combined with any clinical symptoms of development of infection. CONCLUSION: No relationship has been identified between the routine prescription of antibiotics before or during an elective cesarean section and the risk of developing infectious complications in the post-operative period. Antibiotic prophylaxis before surgery should be carried out differentially, taking into account the history and features of the course of this pregnancy.

Acute Dystonia after a Single Dose of Intravenous Metoclopramide during Elective Cesarean Section: A Case Report.

2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Danielle Levin
Keyword(s):  
Single Dose ◽  
Case Report ◽  
Cesarean Section ◽  
Epidural Anesthesia ◽  
Elective Cesarean Section ◽  
Single Administration ◽  
Dystonic Reaction ◽  
Elective Cesarean ◽  
Combined Spinal Epidural Anesthesia ◽  
Spinal Epidural

We would like to present the first report of severe acute dystonic reaction after a single administration of metoclopramide during cesarean section under combined spinal-epidural anesthesia.  During elective cesarean section, a 30-year-old female vomited four times and was treated with 10mg intravenous metoclopramide and 8mg intravenous ondansetron.  Nausea subsided with the antiemetic treatment, but two minutes later, patient had rapid eye blinking, uncontrollable head movement, and became unresponsive.  Bolus of 50mg intravenous diphenhydramine resolved the acute dystonic symptoms within seconds.  Patient was again oriented times three, with no recollection of symptoms, and remained symptom free for the rest of admission. 

scholarly journals Women’s empowerment and elective cesarean section for a single pregnancy: a population-based and multivariate study in Vietnam

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Myriam de Loenzien ◽  
Quoc Nhu Hung Mac ◽  
Alexandre Dumont
Keyword(s):  
Cesarean Section ◽  
Partner Violence ◽  
Negative Impact ◽  
Mode Of Delivery ◽  
Women's Empowerment ◽  
Women’S Empowerment ◽  
Elective Cesarean Section ◽  
Multiparous Women ◽  
Elective Cesarean ◽  
Primiparous Women

Abstract Background Women’s empowerment, and maternal and neonatal health are important targets of the Sustainable Development Goals. Our objective is to examine the relationship between women’s empowerment and elective cesarean section (ECS), focusing on Vietnam, a country where the use of CS has increased rapidly in recent decades, which raises public health concerns. Methods We hypothesized that in the context of the developing biomedicalization of childbirth, women’s empowerment increases the use of ECS due to a woman’s enhanced ability to decide her mode of delivery. By using microdata from the 2013–2014 Multiple Indicator Clusters Survey, we conducted a multivariate analysis of the correlates of ECS. We studied a representative sample of 1343 institutional single birth deliveries. Due to higher ECS rates among multiparous (18.4%) than primiparous women (10.1%) and the potential interaction between parity and other correlates, we used separate models for primiparous and multiparous women. Results Among the indicators of women’s external resources, which include a higher level of education, having worked during the previous 12 months, and having one’s own mobile phone, only education differed between primiparous and multiparous women, with a higher level among primiparous women. Among primiparous women, no resource indicator was significantly linked to ECS. However, considering women’s empowerment facilitated the identification of the negative impact of having had fewer than 3 antenatal care visits on the use of ECS. Among multiparous women, disapproval of intimate partner violence (IPV) was associated with a doubled likelihood of undergoing ECS (odds ratio = 2.415), and living in an urban area also doubled the likelihood of ECS. The positive association with living in the richest household quintile was no longer significant when attitude towards IPV was included in the model. In both groups, being aged 35 or older increased the likelihood of undergoing ECS, and this impact was stronger in primiparous women. Conclusions These results underline the multidimensionality of empowerment, its links to other correlates and its contribution to clarifying the influence of these correlates, particularly for distinguishing between medical and sociocultural determinants. The results advocate for the integration of women's empowerment into policies aimed at reducing ECS rates.

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