scholarly journals Unleashing the immune response to NY-ESO-1 cancer testis antigen as a potential target for cancer immunotherapy

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Afsheen Raza ◽  
Maysaloun Merhi ◽  
Varghese Philipose Inchakalody ◽  
Roopesh Krishnankutty ◽  
Allan Relecom ◽  
...  
Keyword(s):  
Immune Response ◽  
Cancer Immunotherapy ◽  
Cancer Testis Antigen ◽  
Potential Target ◽  
Cancer Testis

scholarly journals Cancer-testis Antigen FATE1 Expression in Adrenocortical Tumors Is Associated with A Pervasive Autoimmune Response and Is A Marker of Malignancy in Adult, but Not Children, ACC

Cancers ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 689 ◽  
Author(s):  
Mabrouka Doghman-Bouguerra ◽  
Pascal Finetti ◽  
Nelly Durand ◽  
Ivy Zortéa S. Parise ◽  
Silviu Sbiera ◽  
...  
Keyword(s):  
Immune Response ◽  
Prognostic Indicator ◽  
Adult Patients ◽  
Autoimmune Response ◽  
Immune Response Gene ◽  
Cancer Testis Antigen ◽  
Adrenocortical Tumors ◽  
Response To Chemotherapy ◽  
Transcription Factor Target ◽  
Cancer Testis

The SF-1 transcription factor target gene FATE1 encodes a cancer-testis antigen that has an important role in regulating apoptosis and response to chemotherapy in adrenocortical carcinoma (ACC) cells. Autoantibodies directed against FATE1 were previously detected in patients with hepatocellular carcinoma. In this study, we investigated the prevalence of circulating anti-FATE1 antibodies in pediatric and adult patients with adrenocortical tumors using three different methods (immunofluorescence, ELISA and Western blot). Our results show that a pervasive anti-FATE1 immune response is present in those patients. Furthermore, FATE1 expression is a robust prognostic indicator in adult patients with ACC and is associated with increased steroidogenic and decreased immune response gene expression. These data can open perspectives for novel strategies in ACC immunotherapy.

scholarly journals Cancer testis antigen Sperm Protein 17 as a new target for triple negative breast cancer immunotherapy

Oncotarget ◽  
2017 ◽  
Vol 8 (43) ◽  
pp. 74378-74390 ◽  
Author(s):  
Leonardo Mirandola ◽  
Elisa Pedretti ◽  
Jose A. Figueroa ◽  
Raffaella Chiaramonte ◽  
Michela Colombo ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Immunotherapy ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Cancer Testis Antigen ◽  
Sperm Protein ◽  
Cancer Testis ◽  
Sperm Protein 17

scholarly journals Cancer-Testis Antigen Peptide Vaccine for Cancer Immunotherapy: Progress and Prospects

2019 ◽  
Vol 12 (5) ◽  
pp. 733-738 ◽  
Author(s):  
Xiao Wei ◽  
Fangjun Chen ◽  
Kai Xin ◽  
Qin Wang ◽  
Lixia Yu ◽  
...  
Keyword(s):  
Cancer Immunotherapy ◽  
Peptide Vaccine ◽  
Cancer Testis Antigen ◽  
Antigen Peptide ◽  
Cancer Testis

scholarly journals The novel cancer-testis antigen A-kinase anchor protein 4 (AKAP4) is a potential target for immunotherapy of ovarian serous carcinoma

2013 ◽  
Vol 2 (5) ◽  
pp. e24270 ◽  
Author(s):  
Sumit Agarwal ◽  
Shikha Saini ◽  
Deepak Parashar ◽  
Archana Verma ◽  
Abhilasha Sinha ◽  
...  
Keyword(s):  
Serous Carcinoma ◽  
The Novel ◽  
Cancer Testis Antigen ◽  
Ovarian Serous Carcinoma ◽  
Anchor Protein ◽  
Potential Target ◽  
Antigen A ◽  
Cancer Testis

BORIS, a novel cancer-testis antigen, is a potential target for immunotherapy in epithelial ovarian cancer

2005 ◽  
Vol 23 (16_suppl) ◽  
pp. 9673-9673
Author(s):  
J. A. Villella ◽  
F. Qian ◽  
B. Keitz ◽  
D. Driscoll ◽  
J. Skipper ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Cancer Testis Antigen ◽  
Potential Target ◽  
Cancer Testis

scholarly journals A novel era of cancer/testis antigen in cancer immunotherapy

2021 ◽  
Vol 98 ◽  
pp. 107889
Author(s):  
Xiaoyan Meng ◽  
Xueqing Sun ◽  
Zhonglong Liu ◽  
Yue He
Keyword(s):  
Cancer Immunotherapy ◽  
Cancer Testis Antigen ◽  
Cancer Testis

Identification of HLA-A24-Restricted CTL Epitope from Cancer-Testis Antigen, NY-ESO-1, and Induction of a Specific Antitumor Immune Response

2004 ◽  
Vol 10 (3) ◽  
pp. 890-896 ◽  
Author(s):  
Hiroshi Yamaguchi ◽  
Fumiaki Tanaka ◽  
Mitsuhiko Ohta ◽  
Hiroshi Inoue ◽  
Masaki Mori
Keyword(s):  
Immune Response ◽  
Antitumor Immune Response ◽  
Cancer Testis Antigen ◽  
Ctl Epitope ◽  
Cancer Testis
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