scholarly journals Evaluation of the optimal combinations of modulation factor and pitch for Helical TomoTherapy plans made with TomoEdge using Pareto optimal fronts

2015 ◽  
Vol 10 (1) ◽  
Author(s):  
Geert De Kerf ◽  
Dirk Van Gestel ◽  
Lobke Mommaerts ◽  
Danielle Van den Weyngaert ◽  
Dirk Verellen
Author(s):  
Mahmood Mohagheghi ◽  
Jayanta Kapat ◽  
Narasimha Nagaiah

In this paper, two configurations of the S-CO2 Brayton cycles (i.e., the single-recuperated and recompression cycles) are thermodynamically modeled and optimized through a multi-objective approach. Two semi-conflicting objectives, i.e., cycle efficiency (ηc) and cycle specific power (Φsp) are maximized simultaneously to achieve Pareto optimal fronts. The objective of maximum cycle efficiency is to have a smaller and less expensive solar field, and a lower fuel cost in case of a hybrid scheme. On the other hand, the objective of maximum specific power provides a smaller power block, and a lower capital cost associated with recuperators and coolers. The multi-objective optimization is carried out by means of a genetic algorithm which is a robust method for multidimensional, nonlinear system optimization. The optimization process is comprehensive, i.e., all the decision variables including the inlet temperatures and pressures of turbines and compressors, the pinch point temperature differences, and the mass flow fraction of the main compressor are optimized simultaneously. The presented Pareto optimal fronts provide two optimum trade-off curves enabling decision makers to choose their desired compromise between the objectives, and to avoid naive solution points obtained from a single-objective optimization approach. Moreover, the comparison of the Pareto optimal fronts associated with the studied configurations reveals the optimum operational region of the recompression configuration where it presents superior performance over the single-recuperated cycle.


2017 ◽  
Vol 18 (3) ◽  
pp. 83-87 ◽  
Author(s):  
Hidetoshi Shimizu ◽  
Koji Sasaki ◽  
Hiroyuki Tachibana ◽  
Natsuo Tomita ◽  
Chiyoko Makita ◽  
...  

Author(s):  
Reinier Gonzalez-Echevarria ◽  
Elisenda Roca ◽  
Rafael Castro-Lopez ◽  
Francisco V. Fernandez ◽  
Javier Sieiro ◽  
...  

2007 ◽  
Vol 6 (4) ◽  
pp. 355-360 ◽  
Author(s):  
José A. Peñagarícano ◽  
Yulong Yan ◽  
Peter Corry ◽  
Eduardo Moros ◽  
Vaneerat Ratanatharathorn

Helical tomotherapy (HT) can be used for the delivery of cranio-spinal axis irradiation (CSAI) without the need for beam matching of conventional linac-based external beam irradiation. The aim of this study is to retrospectively evaluate HT plans used for treatment in nine patients treated with CSAI. Helical tomotherapy cranio-spinal axis irradiation (HT-CSAI) plans were created for each patient. Average length along the cranio-spinal axis of the PTV was 65.6 cm with a range between 53 and 74 cm. Treatment planning optimization and plan evaluation parameters were obtained from the HT planning station for each of the nine patients. PTV coverage by the 95% isodose surface ranged between 98.0 to 100.0% for all nine patients. The clinically acceptable dose variation within the PTV or tolerance range was between 0.7 and 2.5% for all nine patients. Doses to the organs at risk were clinically acceptable. An increasing length along the longitudinal axis of the PTV did not consistently increase the beam-on time indicating that using a larger jaw width had a greater impact on treatment time. With a larger jaw width it is possible to substantially reduce the normalized beam-on treatment time without compromising plan quality and sparing of organs at risk. By using a larger jaw width or lower modulation factor or both, normalized beam-on times were decreased by up to 61% as compared to the other evaluated treatment plans. From the nine cases reported in this study the minimum beam-on time was achieved with a jaw width of 5.0 cm, pitch of 0.287 and a modulation factor of 2.0. Large and long cylindrical volumes can be effectively treated with helical tomotherapy with both clinically acceptable dose distribution and beam-on time.


Robotica ◽  
2008 ◽  
Vol 26 (6) ◽  
pp. 753-765 ◽  
Author(s):  
R. Saravanan ◽  
S. Ramabalan ◽  
C. Balamurugan

SUMMARYA general new methodology using evolutionary algorithms viz., Elitist Non-dominated Sorting Genetic Algorithm (NSGA-II) and Multi-objective Differential Evolution (MODE), for obtaining optimal trajectory planning of an industrial robot manipulator (PUMA 560 robot) in the presence of fixed and moving obstacles with payload constraint is presented. The problem has a multi-criterion character in which six objective functions, 32 constraints and 288 variables are considered. A cubic NURBS curve is used to define the trajectory. The average fuzzy membership function method is used to select the best optimal solution from Pareto optimal fronts. Two multi-objective performance measures namely solution spread measure and ratio of non-dominated individuals are used to evaluate the strength of Pareto optimal fronts. Two more multi-objective performance measures namely optimiser overhead and algorithm effort are used to find computational effort of the NSGA-II and MODE algorithms. The Pareto optimal fronts and results obtained from various techniques are compared and analysed. Both NSGA-II and MODE are best for this problem.


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