scholarly journals Effect of inspiratory muscle training with load compared with sham training on blood pressure in individuals with hypertension: study protocol of a double-blind randomized clinical trial

Trials ◽  
2016 ◽  
Vol 17 (1) ◽  
Author(s):  
Simone Regina Posser ◽  
Carine Cristina Callegaro ◽  
Marina Beltrami-Moreira ◽  
Leila Beltrami Moreira
Keyword(s):  
Blood Pressure ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Study Protocol ◽  
Inspiratory Muscle ◽  
Inspiratory Muscle Training ◽  
Muscle Training ◽  
Double Blind

Inspiratory Muscle Training on Glucose Control in Diabetes: A Randomized Clinical Trial

2020 ◽  
pp. 1-11
Author(s):  
Mariana B. Pinto ◽  
Patrícia M. Bock ◽  
Andressa S.O. Schein ◽  
Juliana Portes ◽  
Raíssa B. Monteiro ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Glucose Control ◽  
Muscle Function ◽  
Respiratory Muscle ◽  
Inspiratory Muscle ◽  
Inspiratory Muscle Training ◽  
Muscle Training ◽  
Fasting Glycemia ◽  
Respiratory Muscle Function

This study evaluated the effects of inspiratory muscle training (IMT) in glucose control and respiratory muscle function in patients with diabetes. It was a randomized clinical trial conducted at the Physiopathology Laboratory of the Hospital de Clínicas de Porto Alegre. Patients with Type 2 diabetes were randomly assigned to IMT or placebo-IMT (P-IMT), performed at 30% and 2% of maximal inspiratory pressure, respectively, every day for 12 weeks. The main outcome measures were HbA1c, glycemia, and respiratory muscle function. Thirty patients were included: 73.3% women, 59.6 ± 10.7 years old, HbA1c 8.7 ± 0.9% (71.6 ± 9.8 mmol/mol), and glycemia 181.8 ± 57.8 mg/dl (10.5 ± 3.2 mmol/L). At the end of the training, HbA1c was 8.2 ±0.3% (66.1 ± 3.3 mmol/mol) and 8.7 ± 0.3% (71.6 ± 3.3 mmol/mol) for the IMT and P-IMT groups, respectively (p = .8). Fasting glycemia decreased in both groups with no difference after training although it was lower in IMT at 8 weeks: 170.0 ± 11.4 mg/dl(9.4 ± 0.6 mmol/L) and 184.4 ± 15.0 mg/dl (10.2 ± 0.8 mmol/L) for IMT and P-IMT, respectively (p < .05). Respiratory endurance time improved in the IMT group (baseline = 325.9 ± 51.1 s and 305.0 ± 37.8 s; after 12 weeks = 441.1 ± 61.7 s and 250.7 ± 39.0 s for the IMT and P-IMT groups, respectively; p < .05). Considering that glucose control did not improve, IMT should not be used as an alternative to other types of exercise in diabetes. Higher exercise intensities or longer training periods might produce better results. The clinical trials identifier is NCT 03191435.

Inspiratory muscle training in patients with diabetic autonomic neuropathy: a randomized clinical trial

2015 ◽  
Vol 25 (4) ◽  
pp. 263-266 ◽  
Author(s):  
Diogo Machado Kaminski ◽  
Beatriz D. Schaan ◽  
Antônio Marcos Vargas da Silva ◽  
Pedro Paulo Soares ◽  
Pedro Dal Lago
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Autonomic Neuropathy ◽  
Diabetic Autonomic Neuropathy ◽  
Inspiratory Muscle ◽  
Inspiratory Muscle Training ◽  
Muscle Training

Home-based inspiratory muscle training in pediatric patients after kidney transplantation: a randomized clinical trial

2020 ◽  
Vol 35 (8) ◽  
pp. 1507-1516
Author(s):  
Raquel P. Carbonera ◽  
Ana Paula O. Barbosa ◽  
Tatiana C. Normann ◽  
Pedro Dal Lago ◽  
Clotilde D. Garcia ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Kidney Transplantation ◽  
Randomized Clinical Trial ◽  
Pediatric Patients ◽  
Inspiratory Muscle ◽  
Inspiratory Muscle Training ◽  
Muscle Training ◽  
Home Based

Abstract P161: Inspiratory Muscle Training and Aerobic Training in the Treatment of Hypertension: Baroreflex Sensitivity, Sympathetic Activity and Endothelial Function Responses

Hypertension ◽  
2016 ◽  
Vol 68 (suppl_1) ◽  
Author(s):  
Janaina B Ferreira ◽  
Valéria Hong ◽  
Otávio Coelho ◽  
Silvia Cavasin ◽  
Fernando Santos ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Endothelial Function ◽  
Arterial Hypertension ◽  
Vascular Function ◽  
Sympathetic Activity ◽  
Baroreflex Sensitivity ◽  
Aerobic Training ◽  
Inspiratory Muscle ◽  
Inspiratory Muscle Training ◽  
Muscle Training

Arterial hypertension is associated to sympathetic hyperactivity and endothelial dysfunction. Aerobic training (AT) is highly recommended to improve vascular function minimizing complications and Inspiratory muscle training (IMT) has demonstrated beneficial effects in this population, especially improving cardiovascular autonomic control. We sought to observe the effects of both training modalities on baroreflex sensitivity, sympathetic activity and endothelial function, in patients with controlled arterial hypertension. 10 patients (55±4 years old, both genders) were included and allocated into two groups: IMT (n=5, 7days/week, 30min/day, load=30%PImax) and AT (n=5, 2days/week, 1hour/day, load=70%HRmax). Both training protocols were performed during 12 weeks. Blood pressure (BP) and heart rate (HR) signals were recorded before and after protocols, as well as the other evaluations, by pulse telemetry (Finometer®PRO) and ECG (PowerLab®). Arterial baroreflex sensitivity was analysed by sequence method. Sympathetic activity was evaluated by microneurography (PowerLab®) and the endothelial function was evaluated by flow mediated dilation (EnVisor CHD, Philips, Bothell, WA, USA). After 12 weeks treatment IMT improved baroreflex sensitvity to both tachycardic and bradycardic responses respectively (BRR Down Gain (mean): IMT=26.51(±1.7)vs15.57(±6.7), AT=13.94(±5.5)vs17.92(±1.6); BRR Up Gain (mean): IMT=17.16(±1.2)vs16.28(±1.1), AT=12.39(±5)vs12.69(±3.3)). Additionally, we observed reduction of sympathetic activity in both groups (IMT:33.23±11.79vs25.07±13.28; AT:29.88±7.07vs24.09±6.37) and improvement of endothelial function independent of the treatment (IMT:6.4±2.18vs7.22±2.08; AT:5.49±7.43vs7.06±3.12). Regarding the responses to inspiratory muscle training and aerobic training on autonomic cardiovascular control and endothelial function in Hypertension, we demonstrated for the first time that IMT and AT present quite similar effects in patients with controlled blood pressure.

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