scholarly journals Long-term survival after pancreatic metastasis resection from breast cancer: a systematic literature review

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Atsuki Nagao ◽  
Tamaki Noie ◽  
Hajime Horiuch ◽  
Haruyasu Yamada ◽  
Masashi Momiyama ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Tumor ◽  
Left Breast ◽  
Pancreatic Metastasis ◽  
Term Survival ◽  
Pancreatic Metastases ◽  
Paraaortic Lymph Nodes ◽  
Simple Mastectomy ◽  
Parasternal Lymph Node ◽  
Mass Lesions

Abstract Background Patients with advanced-stage breast cancer often demonstrate pancreatic metastases. However, pancreatic metastases resection from breast cancer has been rarely performed, with only 20 cases having been reported to date. Case presentation A 49-year-old woman presented to our hospital in September 2003 with complaints of uncontrollable oozing from her left breast tumor. Computed tomography revealed a left breast tumor approximately 9.3 cm in diameter as well as heterogeneously enhanced solid mass lesions with necrotic foci in the pancreatic tail and body, up to 6.2 cm, which were radiologically diagnosed as pancreatic metastases from breast cancer. An emergent left simple mastectomy was performed to control bleeding. After epirubicin and cyclophosphamide hydrate treatment failed to improve her condition, the pancreatic metastases responded to weekly paclitaxel treatment, but eventually regrew. The patient underwent distal pancreatectomy with splenectomy, left adrenalectomy, partial stomach resection, and paraaortic lymph nodes excision in December 2004 after no other metastasis was confirmed. Furthermore, she received radiation therapy for left parasternal lymph node metastasis 6 months later. The patient recovered well. Consequently, she has no evidence of disease > 15 years after pancreatectomy. Conclusions This is the first reported case of pancreatectomy for pancreatic metastases from breast cancer, which was simultaneously diagnosed. Patients with no metastasis other than resectable pancreatic metastases and breast cancer and who possess some sensitivity for chemotherapy may benefit from pancreatectomy.

scholarly journals Excision of metastatic breast cancer from sternum and reconstruction in two patients with solitary metastatic spread

2020 ◽  
Vol 2020 (8) ◽  
Author(s):  
Saifullah Mohamed ◽  
Khurum Mazhar ◽  
Ahmed Osman ◽  
Akshay Patel ◽  
Lakshmi Srinivasan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Carcinoma ◽  
Previous History ◽  
Metastatic Breast ◽  
Extent Of Resection ◽  
Left Breast ◽  
Term Survival ◽  
Metastatic Breast Carcinoma ◽  
History Of ◽  
Treated Breast

Abstract Metastatic breast carcinoma is a relatively common clinical entity. However, the prognosis of oligometastatic and polygometastatic disease differs considerably pertaining to five-year survival. Metastatic breast carcinoma to the sternum has been described as early as 1988. We describe two cases in our institution who presented with solitary sternal metastases with a previous history of treated breast cancer. In both cases, there had been a history of previous left breast cancer treated aggressively with surgical resection and adjuvant oncological therapy and maintenance hormonal therapy. Partial sternectomy or total sternectomy for solitary metastatic sternal deposits is well established with relatively low morbidity and mortality and improvement in quality of life and possible improvement in long-term survival. Furthermore, reconstructive options are inherently dependent on extent of resection performed. These techniques can incorporate the use of sternal plates in order to approximate defects and reinforce the sternum in the setting of partial sternectomy.

scholarly journals METAPLASTIC CARCINOMA OF BREAST : A CASE REPORT

2021 ◽  
pp. 39-40
Author(s):  
Manju Singh ◽  
S N Gole ◽  
S L Nirala ◽  
T Narasimha Murty
Keyword(s):  
Breast Cancer ◽  
Progesterone Receptors ◽  
Left Breast ◽  
Metaplastic Carcinoma ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Metaplastic Breast Cancer ◽  
Biopsy Report ◽  
Simple Mastectomy ◽  
Cell Variant

Metaplastic breast cancer constitute nearly 1 % of all breast carcinoma cases. There is metaplasia of normal epithelial components of the breast into other types. They are highly aggressive with very poor prognosis. Here we present a case of 30 year old female who presented with a breast lump in her left breast associated with dull aching pain. It was 10 x 10 cm in size involving upper inner, upper outer, lower outer quadrants and retroareolar area of left breast. USG was suugestive of BIRADS VI lesion. Axillary lymph nodes were not found enlarged clinically or radiologically. Core biopsy report showed Phylloides tumor of breast. The patient underwent simple mastectomy of left breast and histopathology revealed spindle cell variant of metaplastic breast cancer. The cell blocks sent for immunohistochemistry were negative for estrogen, progesterone receptors and Her2neu receptor. The post surgical treatment of this type of breast cancer is still under study.

Solitary thymic metastasis of breast cancer 13 years after surgery

2017 ◽  
Vol 25 (6) ◽  
pp. 469-471
Author(s):  
Akira Fukunaga ◽  
Yuji Sasamura ◽  
Akio Takada ◽  
Yoshihiro Murakami ◽  
Hirotake Abe ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mediastinal Mass ◽  
Left Breast ◽  
Pathological Examination ◽  
Anterior Mediastinal Mass ◽  
Term Survival ◽  
Initial Surgery ◽  
Appropriate Treatment ◽  
Resected Tumor

A 59-year-old woman was noted to have an anterior mediastinal mass on computed tomography at a regular follow-up 13 years after initial surgery for left breast cancer. Magnetic resonance imaging showed an anterior mediastinal mass. A total thymectomy with excision of surrounding lymphoid tissue was performed. Pathological examination of the resected tumor confirmed the diagnosis of thymic metastasis from breast cancer. The patient has been alive for 6 years after thymectomy. Metastases to the thymus are rare, but long-term survival can be expected with appropriate treatment.

Microcalcification-associated breast cancer: HER2-enriched molecular subtype is associated with mammographic features

2018 ◽  
pp. 20170942 ◽  
Author(s):  
Zhong Nie ◽  
Jian Wang ◽  
Xiao-chun Ji
Keyword(s):  
Breast Cancer ◽  
Tumor Size ◽  
Breast Tumor ◽  
Molecular Subtype ◽  
Univariate Analysis ◽  
Breast Cancers ◽  
Tumor Mass ◽  
Tumor Phenotype ◽  
Mass Lesions ◽  
Small Tumor Size

Purpose: To investigate whether the mammographic features were different between breast cancer HER2-enriched molecular subtype and non-HER2-enriched molecular subtype. Methods: 283 microcalcification-associated breast cancers were identified (HER2-enriched: n = 57; non-HER2-enriched: n = 226). Mammographic tumor mass and calcification features in relation to HER2 molecular subtype were analyzed. Results: On univariate analysis, HER2-enriched molecular subtype rates were significantly higher (a) in tumor size <= 2 cm 33 of 57 [57.9%]) than in tumor size >2 cm lesions (22 of 226 [9.7%]) (p = 0.007), (b) in non-spiculated mass 39 of 57 [68.4%]) than in spiculated mass lesions (18 of 226 [7.9%]) (p = 0.034)，(c) in calcifications extent >2 cm (41of 57 [71.9%]) lesions than in calcifications extent <= 2 cm lesions (16 of 226 [7.1%]) (p < 0.001)and (d) in calcification density ＞20/cm2 (44 of 57 [71.2%]) lesions than in calcification density <= 20/cm2 lesions (13 of 226 [5.8%]) (p = 0.034).On multivariate analysis, three mammographic features (tumor size >2 cm vs size⩽2 cm OR: 0.415 95% CI: 0.215 to 0.802, p = 0.009, spiculated mass vs non-spiculated mass OR: 0.226 95% CI: 0.114 to 0.446, p < 0.001 and calcifications extent >2 cm vs calcifications extent <= 2 cm OR: 7.754, 95% CI: 3.100 to 19.339P < 0.001) were independent predictors. Our results indicated that small tumor size, non-spiculated mass and calcification extent >2 cm are more likely to be HER2 molecular subtype. The discrimination of this model, as quantified by the AUC, was 0.751 (95%CI: 0.701 to 0.854). Conclusion: Our study presents a prediction model that incorporates the mammographic features of tumor size, non-spiculated mass and calcification extent, which can potentially be used to preoperative predict breast cancer HER2-enriched subtype. Advancesinknowledge: Mammographic features can noninvasively visualize breast tumor phenotype characteristics.

scholarly journals EUS-FNA Diagnosis with Core Biopsy of Pancreatic Metastases from Primary Breast Cancer

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Samuel Galante Romanini ◽  
Juan Pablo Román Serrano ◽  
Juliana Silveira Lima de Castro ◽  
Isabela Trindade Torres ◽  
Alex Ingold ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Primary Breast Cancer ◽  
Core Biopsy ◽  
Rare Event ◽  
Needle Aspiration ◽  
Pancreatic Metastasis ◽  
Initial Manifestation ◽  
Primary Tumors ◽  
Pancreatic Metastases ◽  
A Site

Background. The pancreas as a site of metastasis of other primary tumors is a rare event. Pancreatic metastases may occur years after the start of treatment of a neoplasm of another organ or may be the initial manifestation of an unidentified primary tumor. The most commonly reported primary sites for pancreatic metastases are the kidneys, lungs, breast, bowel, and skin (melanoma). Case Summary. The authors report a case of pancreatic metastasis derived from a primary breast cancer that underwent endoscopic ultrasound fine-needle aspiration (EUS-FNA) core biopsy to obtain tissue, which made it possible to perform an immunohistochemical study. Conclusion. We emphasize the importance of outpatient follow-up after the treatment of a neoplasia and the completion of control exams. In addition, we should always be aware of the finding of a secondary lesion in patients who have already been diagnosed with cancer, even if it is located in unusual organs, as in this case, where two metastases of a breast carcinoma to the pancreas were detected.

scholarly journals Intrinsic Breast Tumor Subtypes, Race, and Long-Term Survival in the Carolina Breast Cancer Study

2010 ◽  
Vol 16 (24) ◽  
pp. 6100-6110 ◽  
Author(s):  
Katie M. O'Brien ◽  
Stephen R. Cole ◽  
Chiu-Kit Tse ◽  
Charles M. Perou ◽  
Lisa A. Carey ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Tumor ◽  
Term Survival ◽  
Long Term Survival ◽  
Cancer Study ◽  
Tumor Subtypes ◽  
Breast Cancer Study ◽  
Carolina Breast Cancer Study

scholarly journals Temporary spontaneous regression of male breast cancer: a case report

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Kaoru Katano ◽  
Yutaka Yoshimitsu ◽  
Takahiro Kyuno ◽  
Yusuke Haba ◽  
Tsutomu Maeda ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Male Breast Cancer ◽  
Breast Tumor ◽  
Spontaneous Regression ◽  
Left Breast ◽  
Male Breast ◽  
Atypical Cells

Abstract Background Spontaneous regression (SR) of a malignant tumor is the partial or complete disappearance of primary or metastatic tumor tissue in the absence of treatment, which can be temporary or permanent. Here, we report an extremely rare case of male breast cancer that exhibited temporary SR followed by reappearance 8 months after tumor disappearance. Case presentation A 70-year-old man presented at our hospital with a primary complaint of pain and a lump in his left breast. Ultrasonography revealed a hypoechoic lesion measuring 12 mm × 10 mm × 8 mm. Fine-needle aspiration cytology revealed numerous necrotic and degenerated cells and few sheet-like clusters of atypical ductal epithelial cells. The atypical cells had mildly enlarged nuclei with nucleoli, were focally overlapped and formed tubular patterns. The cytological diagnosis indicated a suspicion of malignancy. Core needle biopsy (CNB) revealed necrotic and degenerated cells with microcalcification. The pathological diagnosis was indeterminate because there was no area of viable atypical cells. An excisional biopsy of the left breast lesion was scheduled one month later. However, it was difficult to detect the tumor during physical examination and ultrasonography performed 1 month after the patient’s first visit. The operation was canceled, and the patient received follow-up observation. After 8 months of follow-up, ultrasonography and computed tomography (CT) revealed reappearance of a 0.6-cm-diameter breast tumor in the same place. CNB was performed again and revealed invasive ductal carcinoma. A total mastectomy with sentinel lymph node biopsy was performed 13 months after the first tumor disappeared. Histopathological examination revealed invasive cribriform carcinoma without sentinel lymph node metastasis. The patient did not have any complications, and adjuvant therapy with tamoxifen was started. The patient was alive without recurrence 7 months after surgery. Conclusions Temporary SR followed by tumor reappearance can occur in breast cancer cases, and it is important to follow patients even if their breast tumor has seemingly disappeared. When breast tumors disappear without treatment, clinicians must be aware of the possibility of SR of cancer and should follow the patient for early detection of tumor reappearance.

Sign in / Sign up

Export Citation Format

Share Document