scholarly journals Intestinal FDG-PET/CT imaging of an Eritrean with schistosomiasis seen in Denmark

2019 ◽  
Vol 3 (1) ◽  
Author(s):  
Ata Daghigh ◽  
Julie Marie Grüner ◽  
Peter Mørup

Abstract Background Schistosomiasis is one of the most common parasitic diseases in subtropical and tropical areas and still is considered of public health significance. This disease affects about 200 million people around the world. Intestinal schistosomiasis is mainly diagnosed by parasitological, serological, and molecular methods. Case presentation A 36-year-old Eritrean man who had lived in Denmark for the past 3 years presented to the hospital with 4 months’ history of abdominal pain, back pain, and weight loss of 12 kg. He underwent 18F-FDG-PET/CT scanning. The scan findings were consistent with schistosomiasis, which were confirmed by serological and pathological tests. Conclusion PET/CT is a common modality neither to detect schistosomes nor to diagnose schistosomiasis. A presumptive diagnosis can be made based on coincidence of high FDG uptake in visceral lymph nodes below the diaphragm and in relation to abdominal viscera, travel history suggestive of schistosome infection, and exclusion of other causes of abdominal pain.

2021 ◽  
Author(s):  
Vincent Fleury ◽  
Bruno Maucherat ◽  
Daniela Rusu ◽  
Frédéric Dumont ◽  
Caroline Rousseau

Abstract Background The vaccination immune response may induced false-positive 18F-FDG PET/CT uptake.Case presentationAn extended supraclavicular lymph nodal activation after Coronavirus Disease 2019 (Covid-19) vaccination revealed on 18F-FDG PET/CT mimics a Virchow nodule in a patient with medical history of well-differentiated appendicular adenocarcinoma. Conclusion This case highlights a nodal activation beyond axillary area and the importance of documenting vaccination history at the time of scanning to avoid false-positive results.


2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Vincent Fleury ◽  
Bruno Maucherat ◽  
Daniela Rusu ◽  
Frédéric Dumont ◽  
Caroline Rousseau

Abstract Background The vaccination immune response may induce false-positive 18F-FDG PET/CT uptake. Case presentation An extended supraclavicular lymph nodal activation after coronavirus disease 2019 (COVID-19) vaccination revealed on 18F-FDG PET/CT mimics a Virchow nodule in a patient with medical history of well-differentiated appendicular adenocarcinoma. Conclusion This case highlights a nodal activation beyond axillary area and the importance of documenting vaccination history at the time of scanning to avoid false-positive results.


2017 ◽  
Vol 17 (1) ◽  
pp. e149
Author(s):  
Mercedes Gironella ◽  
Juan Alfons Soler ◽  
Marc Simó ◽  
Carlos Palacio ◽  
Julia Montoro ◽  
...  

2019 ◽  
Vol 44 (7) ◽  
pp. e442-e444
Author(s):  
Zakieh Nasiri ◽  
Soroush Zarehparvar Moghadam ◽  
Zahra Kiamanesh ◽  
Farshad Emami ◽  
Ramin Sadeghi
Keyword(s):  
Fdg Pet ◽  
Pet Ct ◽  
18F Fdg ◽  

2010 ◽  
Vol 46 (5) ◽  
pp. 577-582 ◽  
Author(s):  
Gaëlle Guettrot-Imbert ◽  
Julien Haroche ◽  
Gilles Grimon ◽  
Frédéric Charlotte ◽  
Jacques Ninet ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Pet Ct ◽  

QJM ◽  
2018 ◽  
Vol 111 (9) ◽  
pp. 593-593
Author(s):  
S C Donnelly

2019 ◽  
Vol 3 (4) ◽  
pp. 1-6 ◽  
Author(s):  
Mohamed Dafaalla ◽  
Nicholas Weight ◽  
Verran Cajic ◽  
Uday Dandekar ◽  
Kishore Gopalakrishnan ◽  
...  

Abstract Background Infective endocarditis secondary to Mycobacterium chimaera can present with classical constitutional symptoms of infective endocarditis but can be blood culture negative and without vegetations on transthoracic or transoesophageal echocardiogram. Patients with prosthetic valves are at particularly high risk. Case summary We present two patients who were diagnosed with infective endocarditis secondary to M. chimaera infection. They presented similarly with pyrexia of unknown origin and night sweats. Both patients had previously undergone aortic valve replacement; one with a tissue valve and the other with a metallic valve. New cardiac murmurs were evident on auscultation, but clinical examination showed no peripheral stigmata of endocarditis. Transoesophageal echo and transthoracic echo were both unremarkable, as were serial blood cultures. FDG PET CT scan was the key investigation, which showed increased uptake in the spleen beside other areas. Histopathology and mycobacterial cultures confirmed the diagnosis of M. chimaera infection in both cases. The first patient completed medical therapy and is now fit and well. However, the second patient unfortunately developed disseminated infection causing death. Discussion The management of M. chimaera infective endocarditis is challenging, often with delayed diagnosis and poor outcomes. In the context of negative blood cultures and inconclusive echocardiograms where there remains a high index of suspicion for endocarditis, FDG PET CT scanning can be a crucial diagnostic importance and should be considered early in patients with prosthetic valves.


Rheumatology ◽  
2019 ◽  
Vol 59 (6) ◽  
pp. 1407-1415 ◽  
Author(s):  
Daphne M Peelen ◽  
Ben G J C Zwezerijnen ◽  
Esther J Nossent ◽  
Lilian J Meijboom ◽  
Otto S Hoekstra ◽  
...  

Abstract Objectives The reversibility of interstitial lung disease (ILD) in SSc is difficult to assess by current diagnostic modalities and there is clinical need for imaging techniques that allow for treatment stratification and monitoring. 18F-Fluorodeoxyglucose (FDG) PET/CT scanning may be of interest for this purpose by detection of metabolic activity in lung tissue. This study aimed to investigate the potential role of 18F-FDG PET/CT scanning for the quantitative assessment of SSc-related active ILD. Methods 18F-FDG PET/CT scans and high resolution CT scans of eight SSc patients, including five with ILD, were analysed. For comparison, reference groups were included: eight SLE patients and four primary Sjögren’s syndrome (pSS) patients, all without ILD. A total of 22 regions of interest were drawn in each patient at apical, medial and dorsobasal lung levels. 18F-FDG uptake was measured as mean standardized uptake value (SUVmean) in each region of interest. Subsequently, basal/apical (B/A) and medial/apical (M/A) ratios were calculated at patient level (B/A-p and M/A-p) and at tissue level (B/A-t and M/A-t). Results SUVmean values in dorsobasal ROIs and B/A-p ratios were increased in SSc with ILD compared with SSc without ILD (P = 0.04 and P = 0.07, respectively), SLE (P = 0.003 and P = 0.002, respectively) and pSS (P = 0.03 and P = 0.02, respectively). Increased uptake in the dorsobasal lungs and increased B/A-t ratios corresponded to both ground glass and reticulation on high resolution CT. Conclusion Semi-quantitative assessment of 18F-FDG PET/CT is able to distinguish ILD from non-affected lung tissue in SSc, suggesting that it may be used as a new biomarker for SSc-ILD disease activity.


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