scholarly journals Myocardial strain analysis as a non-invasive screening test in the diagnosis of stable coronary artery disease

2021 ◽  
Vol 73 (1) ◽  
Author(s):  
Nehzat Akiash ◽  
Mohammad Mohammadi ◽  
Hoda Mombeini ◽  
Akbar Nikpajouh
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Longitudinal Strain ◽  
Low Cost ◽  
Stable Coronary Artery Disease ◽  
Global Longitudinal Strain ◽  
Myocardial Strain ◽  
Strain Analysis ◽  
Myocardial Strain Analysis ◽  
Artery Disease

Abstract Background Coronary artery disease (CAD) is one of the most prevalent diseases around the world; however, finding the best noninvasive, low-cost, and more easily accessible test for its screening has been a challenge for several years. Eighty-nine patients suspected of stable CAD underwent 2D-speckle-tracking echocardiography (2DSTE) at resting position and offline longitudinal myocardial strain analysis, followed by coronary angiography. The correlation of the global longitudinal strain (GLS) and territorial longitudinal strain (TLS) with significant CAD (70% and more stenosis in at least one coronary artery) was then evaluated. Results The statistical analysis showed a significant correlation between low GLS and significant CAD (P=0.0001). The results also showed a significant correlation between low TLS and significant CAD in the left and right coronary artery territories. The optimal cut-off point of GLS for the detection of significant CAD was −19.25, with a sensitivity of 76.5% and specificity of 76.6%. Conclusion This study confirmed the usefulness of 2DSTE myocardial strain analysis in diagnosis of CAD for detecting the affected coronary arteries using GLS and SLS.

scholarly journals LEFT VENTRICULAR GLOBAL LONGITUDINAL STRAIN ACROSS THE SPECTRUM OF COMPLEXITY OF STABLE CORONARY ARTERY DISEASE

2021 ◽  
Vol 39 (Supplement 1) ◽  
pp. e199
Author(s):  
Laima Caunite ◽  
Ginta Kamzola ◽  
Evija Knoka ◽  
Mairita Mazule ◽  
Renate Pelcberga ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Longitudinal Strain ◽  
Stable Coronary Artery Disease ◽  
Global Longitudinal Strain ◽  
Left Ventricular ◽  
Artery Disease

scholarly journals Correlation between Myocardial Strain and Angiographic Severity of Coronary Artery Disease in Non-ST-Elevation Myocardial Infarction Patient

2020 ◽  
Vol 5 (03) ◽  
Author(s):  
Md. Al-Amin ◽  
Md. Mashiul Alam ◽  
Tanjima Parvin ◽  
Chaudhury Meshkat Ahmed ◽  
Md. Zainal Abedin ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Longitudinal Strain ◽  
Global Longitudinal Strain ◽  
Myocardial Strain ◽  
St Elevation Myocardial Infarction ◽  
Gensini Score ◽  
St Elevation ◽  
Artery Disease

Background and objectives: Noninvasive assessment of coronary artery disease severity remains a clinical challenge. Myocardium subtended by obstructive coronary artery disease may show reduced left ventricular strain. The present study was intended to investigate whether this reduction of strain value correlates with increasing severity of coronary artery disease in Non-ST-Elevation Myocardial Infarction (NSTEMI) patients. Methods: This cross sectional study included 86 patients of NSTEMI. We assessed myocardial strain in global longitudinal strain (GLS) value using two dimensional speckle tracking echocardiography (2DSE). We performed coronary angiogram of the same patients and documented presence or absence of significant disease, number of affected vessels and Gensini score. Significant coronary artery was defined as ≥70% stenosis in any major coronary artery and or ≥50% stenosis in left main coronary artery. Results: Global longitudinal strain value was significantly lower in the significant coronary artery disease group (-13.5±3.4% vs. -19.01±2.3%) (p < 0.001). GLS declined proportionately with increasing severity of coronary artery disease defined by number of affected vessels (p < 0.001). Spearman’s rank correlation coefficient test between GLS value and Gensini score showed that the two variables maintained a linear but inverse relationship (ρ = 0.816, p < 0.001) that implies decreasing GLS is associated with increasing Gensini score. Multivariate logistic regression analysis found global longitudinal strain as an independent predictor of coronary artery disease. Conclusion: Myocardial strain assessed in global longitudinal strain value correlates with angiographic severity of coronary artery disease in patients with Non-ST-Elevation Myocardial Infarction.

Additional diagnostic accuracy of global longitudinal strain at peak dobutamine stress in patients with moderate pretest probability of coronary artery disease

2020 ◽  
Vol 37 (8) ◽  
pp. 1222-1232
Author(s):  
Ahmed A. Elamragy ◽  
Mohamed A. Abdelwahab ◽  
Dalia R. Elremisy ◽  
Mohamed Hassan ◽  
Waleed A. Ammar ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Diagnostic Accuracy ◽  
Longitudinal Strain ◽  
Global Longitudinal Strain ◽  
Dobutamine Stress ◽  
Pretest Probability ◽  
Artery Disease

scholarly journals Speckle-tracking during dipyridamole stress echocardiography in the detection of myocardial ischemia in patients with suspected coronary artery disease

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
L Moderato ◽  
G Pastorini ◽  
D Lazzeroni ◽  
A Monello ◽  
G Rusticali ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Stress Echocardiography ◽  
Longitudinal Strain ◽  
Global Longitudinal Strain ◽  
Model Average ◽  
Significant Difference ◽  
Artery Disease ◽  
Dipyridamole Stress Echocardiography ◽  
Dipyridamole Stress

Abstract Background The aim of this study was to investigate the incremental value of global longitudinal strain (GLS), postsystolic strain index (PSI) and prestretch (PSE) by automated function imaging with respect to wall motion (WM) and coronary flow reserve (CFR) for the diagnosis of significant coronary artery disease (CAD) during dipyridamole stress echocardiography. Methods We retrospectibely enrolled 227 patients with known or suspected CAD, approaching our echo lab to perform a DSE; all patient underwent coronary angiography within 1 month for clinical reasons. Obstructive CAD was defined as the evidence of &gt;70% stenosis during coronary angiogram. Obstructive CAD was detected in 143 (63%) patients, while 84 (37%) had no significant CAD. Global longitudinal strain, PSI and PSE were measured at rest and peak of the stress (after 6 minutes of 0,84mg/kg of dipyridamole infusion). Results Patient with CAD showed a significantly lower GLS at rest (−16.9±4.2 vs −18.6±3.4; p&lt;0.01) and peak (14.9±3.8 vs −21.50±3.3; p&lt;0.01) Figure A; the behavior of GLS was opposite, in patient with CAD showed an increase while in patient without CAD a significant decrease after dipyridamole infusion. There was also a significant difference between groups for Delta PSI (PSIpeak − PSIrest) and Delta PSE (PSEpeak − PSErest), respectively 126±145 vs −40±97, (p&lt;0.01) and 108±163 vs −41±106 (p&lt;0.01) Figure C. ROC analyses produced a statistically valid model: Average GLS at peak (p 0.001; AUC=0.906, cut-off value −18%, sensitivity 83% and specificity 82%); on the basis of these results, we compared WM and myocardial deformation analysis and GLS was superior to CFR LAD, Delta EF, Delta ESV and Delta WMI (Figure B). Conclusions GLS, PSE and PSI show an opposite response to dipyridamole, in patients with CAD in patient without CAD and show much higher sensitivity and specificity compared to the conventional parameters like WMI, EF and CFR in detecting CAD Funding Acknowledgement Type of funding source: None

Global Longitudinal Strain at Rest for Detection of Coronary Artery Disease in Patients without Diabetes Mellitus

2018 ◽  
Vol 38 (3) ◽  
pp. 413-421 ◽  
Author(s):  
Hou-juan Zuo ◽  
Xiu-ting Yang ◽  
Qi-gong Liu ◽  
Yan Zhang ◽  
He-song Zeng ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Longitudinal Strain ◽  
Global Longitudinal Strain ◽  
Artery Disease
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