scholarly journals OPUS study: Suicidal behaviour, suicidal ideation and hopelessness among patients with first-episode psychosis

2002 ◽  
Vol 181 (S43) ◽  
pp. s98-s106 ◽  
Author(s):  
M. Nordentoft ◽  
P. Jeppesen ◽  
M. Abel ◽  
P. Kassow ◽  
L. Petersen ◽  
...  

BackgroundPatients with first-episode psychosis comprise a high-risk group in terms of suicide.AimsTo identify predictive factors for suicidal behaviour and to examine the effect of integrated treatment on suicidal behaviour and hopelessness.MethodA total of 341 patients with a first-episode schizophrenia-spectrum disorder were randomised to integrated treatment or treatment as usual.ResultsDuring the 1-year follow-up period, 11% attempted suicide. This was associated with female gender, hopelessness, hallucinations and suicide attempt reported at baseline, with the two latter variables being the only significant ones in the final multivariate model. The integrated treatment reduced hopelessness.ConclusionsHallucinations and suicide attempt before inclusion in the study were the most significant predictors of suicide attempt in the follow-up period.

2018 ◽  
Vol 44 (suppl_1) ◽  
pp. S374-S374
Author(s):  
Rosa Ayesa-Arriola ◽  
Jose Maria Pelayo-Teran ◽  
Javier-David Lopez-Morinigo ◽  
Manuel Canal-Rivero ◽  
Esther Setien-Suero ◽  
...  

2010 ◽  
Vol 116 (1) ◽  
pp. 1-8 ◽  
Author(s):  
J. Robinson ◽  
M.G. Harris ◽  
S.M. Harrigan ◽  
L.P. Henry ◽  
S. Farrelly ◽  
...  

2005 ◽  
Vol 186 (5) ◽  
pp. 394-399 ◽  
Author(s):  
Bent Rosenbaum ◽  
Kristian Valbak ◽  
Susanne Harder ◽  
Per Knudsen ◽  
Anne Køster ◽  
...  

BackgroundFirst-episode psychosis intervention may improve the course and outcome of schizophrenic disorders.AimsTo describe the Danish National Schizophrenia Project and to measure the outcome of two different forms of intervention after 1 year, compared with standard treatment.MethodA prospective, longitudinal, multicentre investigation included 562 patients, consecutively referred over a 2-year period, with a first episode of psychosis. Patients were allocated to supportive psychodynamic psychotherapy as a supplement to treatment as usual, an integrated, assertive, psychosocial and educational treatment programme or treatment as usual.ResultsThere was a non-significant tendency towards greater improvement in social functioning in the integrated treatment group and the supportive psychodynamic psychotherapy group compared with the treatment as usual group. Significance was reached for some measures when the confounding effect of drug and alcohol misuse was included.ConclusionsIntegrated treatment and supportive psychodynamic psychotherapy in addition to treatment as usual may improve outcome after 1 year of treatment for people with first-episode psychosis, compared with treatment as usual alone.


2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Ricardo Coentre ◽  
Alexandra Fonseca ◽  
Tiago Mendes ◽  
Ana Rebelo ◽  
Elisabete Fernandes ◽  
...  

Abstract Background Suicide is one of the main causes of excess of premature death in psychotic patients. Published studies found that suicide risk begins in ultra-high risk of psychosis and continues in early years of the disease. Previous studies identifying predictive and risk factors associated with suicidality in first-episode psychosis (FEP) are highly inconsistent. Also, there are relatively few longitudinal studies on suicidal behaviour in FEP. The aim of this study was to examine prevalence, evolution and predictors of suicidal behaviour at baseline and the 12-month follow-up in patients presenting with FEP. Methods One hundred and eighteen patients presenting with FEP were recruited from two early psychosis units in Portugal. A comprehensive assessment examining socio-demographic and clinical characteristics was administered at baseline and the 12-month follow-up. Odds ratio were calculated using logistic regression analyses. McNemar test was used to evaluate the evolution of suicidal behaviour and depression prevalence from baseline to 12 months of follow-up. Results Follow-up data were available for 60 participants from the 118 recruited. Approximately 25.4% of the patients had suicidal behaviour at the baseline evaluation, with a significant reduction during the follow-up period to 13.3% (p = 0.035). A multivariate binary logistic regression showed that a history of suicidal behaviour and depression at baseline independently predicted suicidal behaviour at baseline, and a history of suicidal behaviour and low levels of total cholesterol predicted suicidal behaviour at the 12-month follow-up. A significant proportion of patients also had depression at the baseline evaluation (43.3%), with the last month of suicidal behaviour at baseline independently predicting depression at this time. Conclusions The findings of our study indicate that suicidal behaviour was prevalent on the year after FEP. Patients with a history of suicidal behaviour, depression at baseline and low levels of cholesterol should undergo close evaluation, monitoring and possible intervention in order to reduce suicide risk in the early phases of psychosis.


2006 ◽  
Vol 86 ◽  
pp. S57
Author(s):  
J. Robinson ◽  
M.G. Harris ◽  
L.P. Henry ◽  
H.P. Yuen ◽  
S. Farrelly ◽  
...  

2017 ◽  
Vol 256 ◽  
pp. 13-20 ◽  
Author(s):  
Manuel Canal-Rivero ◽  
J.D. Lopez-Moriñigo ◽  
M.L. Barrigón ◽  
S. Perona-Garcelán ◽  
C. Jimenez-Casado ◽  
...  

2007 ◽  
Vol 22 ◽  
pp. S84 ◽  
Author(s):  
M. Nordentoft ◽  
M. Bertelsen ◽  
A. Thorup ◽  
L. Petersen ◽  
J. Ahlenschleger ◽  
...  

2012 ◽  
Vol 60 (5) ◽  
pp. S284-S285 ◽  
Author(s):  
Z. Shahrivar ◽  
J. Alaghband-Rad ◽  
J. Mahmoudi Gharaie ◽  
A. Seddigh ◽  
N. Salesian ◽  
...  

2007 ◽  
Vol 191 (S51) ◽  
pp. s140-s146 ◽  
Author(s):  
Mette Bertelsen ◽  
Pia Jeppesen ◽  
Lone Petersen ◽  
Anne Thorup ◽  
Johan ⊘hlenschlæger ◽  
...  

BackgroundThose with first-episode psychosis are at high-risk of suicideAimsTo identify predictive factors for suicidal thoughts, plans and attempts, and to investigate the rate of suicides and other deaths during the 5 years after first diagnosis and initiation of treatmentMethodA longitudinal, prospective, 5-year follow-up study of 547 individuals with first-episode schizophrenia spectrum psychosis. Individuals presenting for their first treatment in mental health services in two circumscribed urban areas in Denmark were included in a randomised controlled trial of integrated v. standard treatment. All participants were followed in the Danish Cause of Death Register for 5 years. Suicidal behaviour and clinical and social status were assessed using validated interviews and rating scales at entry, and at 1- and 2-year follow-upsResultsSixteen participants died during the follow-up. We found a strong association between suicidal thoughts, plans and previous attempts, depressive and psychotic symptoms and young age, and with suicidal plans and attempts at 1- and 2-year follow-upConclusionsIn this first-episode cohort depressive and psychotic symptoms, especially hallucinations, predicted suicidal plans and attempts, and persistent suicidal behaviour and ideation were associated with high risk of attempted suicide


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