Re-Thinking the Roles of Pathogens and Mutualists: Exploring the Continuum of Symbiosis in the Context of Microbial Ecology and Evolution

Systems of classification are important for guiding research activities and providing a common platform for discussion and investigation. One such system is assigning microbial taxa to the roles of mutualists and pathogens. Yet, there are often challenges and even inconsistencies in reports of research findings when microbial taxa display behaviors outside of these two static conditions (e.g. commensal). Over the last two decades, there has been some effort to highlight a continuum of symbiosis, wherein certain microbial taxa may exhibit mutualistic or pathogenic traits depending on environmental contexts, life stages, and plant host associations. However, gaps remain in understanding how to apply the continuum approach to host-microbe pairs across a range of environmental and ecological factors. This commentary presents an alternative framework for evaluating the continuum of symbiosis using dominant archetypes that define symbiotic ranges. We focus particularly on fungi and bacteria, though we recognize that archaea and other microeukaryotes play important roles in host-microbe interactions that may be described by this approach. This framework is centered in eco-evolutionary theory and aims to enhance communication among researchers, as well as prioritize holistic consideration of the factors shaping microbial life strategies. We discuss the influence of plant-mediated factors, habitat constraints, co-evolutionary forces, and the genetic contributions which shape different microbial lifestyles. Looking to the future, using a continuum of symbiosis paradigm will enable greater flexibility in defining the roles of target microbes and facilitate a more holistic view of the complex and dynamic relationship between microbes and plants.

Volatility spillovers among G7, E7 stock markets and cryptocurrencies

PurposeThe existence of long memory and persistent volatility characteristics of cryptocurrencies justifies the investigation of return and volatility/shock spillovers between traditional financial market asset classes and cryptocurrencies. The purpose of this paper is to investigate the dynamic relationship between the cryptocurrencies, namely Bitcoin and Ethereum, and stock market indices of G7 and E7 countries to analyze the return and volatility spillover patterns among these markets by means of multivariate (MGARCH) approach.Design/methodology/approachApplying the newly developed VAR-GARCH-in mean framework with the BEKK representation, the empirical results reveal that there exists an evidence of mean and volatility spillover effects among Bitcoin and Ethereum as the proxies for the cryptocurrencies, and stock markets reviewed.FindingsInterestingly, the direction of the return and volatility spillover effects is unidirectional in most E7 countries, but bidirectional relationship was found in most G7 countries. This can be explained as the presence of a strong return and volatility interaction among G7 stock markets and crypto market.Originality/valueOverall, the results of this study are of particular interest for portfolio management since it provides insights for financial market participants to make better portfolio allocation decisions. It is also increasingly important to understand the volatility transmission mechanism across these markets to provide policymakers and regulatory bodies with guidance to eliminate the negative impact of cryptocurrency's volatility on the stability of financial markets.

STREAMING-tag system reveals spatiotemporal relationships between transcriptional regulatory factors and transcriptional activity

Transcription is a dynamic process that stochastically switches between the ON and OFF states. To detect the dynamic relationship among protein clusters of RNA polymerase II (RNAPII) and coactivators, gene loci, and transcriptional activity, we inserted an MS2 repeat, a TetO repeat, and inteins with a selection marker just downstream of the transcription start site (TSS). By optimizing the individual elements, we have developed the Spliced TetO REpeAt, MS2 repeat, and INtein sandwiched reporter Gene tag (STREAMING-tag) system. Clusters of RNAPII and BRD4 were observed proximally to the TSS of Nanog when the gene was transcribed in mouse embryonic stem cells. In contrast, clusters of MED19 and MED22 Mediator subunits were constitutively located near the TSS. Thus, the STREAMING-tag system revealed the spatiotemporal relationships between transcriptional activity and protein clusters near the gene. This powerful tool is useful for quantitatively understanding dynamic transcriptional regulation in living cells.

The dynamics of CO2 emissions and economic growth: A comparative analysis using symbolic time series

The aim of this paper is to analyze the dynamic relationship between economic growth and CO2 emissions for a set of 98 countries over the lengthy period from 1951 to 2014. We describe the topology and hierarchy of countries and introduce a different concept of economic performance based on the idea of dynamic regimes. These regimes are defined by the average levels of per-capita CO2 emissions and the growth rates of per-capita GDP. By presenting a nonparametric clustering technique, the paper identifies two main groups. One cluster can be identified as the group of developed countries, which presents a homogeneous structure and tends toward more similar dynamics over time. The other cluster, associated with developing countries, is homogeneous but the dynamics of the countries do not show convergence. The study also finds some, though little, mobility between the groups.

The Conceptual Framework of Economic Cooperation and Integration between OIC: Empirical Evidence on Effects of Trade on Cooperation and Integration

Objective - This study aims to illustrate the conceptual framework of economic cooperation and integration between OIC countries. It also highlighted on Economic cooperation and integration theory. Methodology - This paper follows descriptive analysis approach to describe the conceptual framework of cooperation and integration between OIC countries. This paper describes the conceptual framework of economic cooperation and integration between OIC. Itexplores the channels through which trade can contribute to cooperation and integration. This study highlighted the cooperation between OIC in the light of economic integration theory. Findings - The results of this study discover the dynamic relationship between trade balance and macroeconomic elements. Novelty - This study also explains the empirical evidence on effects of trade on cooperation and integration. The study recommended to compare the results with European Union to understand the effects of trade on cooperation and integration between OIC countries. Type of Paper - Literature. Keywords: Economic Cooperation, Economic integration theory, Trade Balance and Macroeconomic Elements.

Dynamic Relationship Study between the Observed Seismicity and Spatiotemporal Pattern of Lineament Changes in Palghar, North Maharashtra (India)

The Palghar region (north Maharashtra, India), located in the northwestern part of the stable continental region of India, experienced a low magnitude earthquake swarm, which was initiated in September 2018 and is continuing to date (as of October 2021). From December 2018 to December 2020, ~5000 earthquakes with magnitudes from M1.2 to M3.8 occurred in a small region of 20 × 10 km2. These earthquakes were probably triggered by fluid migration during seasonal rainfall. In this study, we have used multi-temporal Landsat satellite data of the year 2000, 2015, 2018, 2019, and 2020, extracted lineaments, and studied the changes in frequency and pattern of lineaments before and after the initiation of the swarm in the Palghar region. An increase in the lineament density and amount of rainfall are found to be associated with the increasing frequency of earthquakes.

A Developmental Study of Mirror-Gazing-Induced Anomalous Self-Experiences and Self-Reported Schizotypy from 7 to 28 Years of Age

<b><i>Introduction:</i></b> The mirror-gazing task (MGT) is an experimental paradigm inducing anomalous perceptions and anomalous experiences of self-face (ASEs) in the general population, ranging from changes in light and color, to face deformation, to experiencing one’s specular image as another identity. Subclinical ASEs have been related to the emergence of the risk for developing psychotic disorders, and inducing such states in the general population could shed light on the factors underlying interindividual differences in proneness to these phenomena. We aimed to examine the influence of schizotypal personality traits on proneness to experiencing induced ASEs from a developmental perspective, from childhood to adulthood. <b><i>Methods:</i></b> Two hundred and sixteen children, adolescents, and young adults participated in the MGT, and their schizotypal personality traits were assessed with the Schizotypal Personality Questionnaire. Statistical analyses assessed the relationship between schizotypy dimensions and induced ASEs, and we further tested their dynamic relationship as function of age (from childhood to adulthood). <b><i>Results:</i></b> Results confirmed the developmental trajectory of the different schizotypy dimensions, with scores peaking during adolescence, and proneness to induced ASEs seemed to follow a similar developmental trajectory. Moreover, positive (<i>p</i> = 0.001) and disorganized (<i>p</i> = 0.004) dimensions were found to contribute to the proneness to experiencing induced ASEs. Finally, the developmental model showed that positive schizotypy (<i>p</i> = 0.035) uniquely distinguished between experiencing other-identity phenomena between childhood and adulthood. <b><i>Conclusion:</i></b> This study has the potential to inform research on early detection of psychosis through a developmental approach and links the concept of schizotypy with processes of perceptual self-distortions.

“You’re My Person”

Belonging can involve social acceptance, feelings of professor pedagogical caring, and a sense of university belonging. This chapter seeks to help readers understand the complex and dynamic relationship process, drawing from a variety of contemporary sources and contextual factors. The transition to new relationships is discussed, with particular consideration of the difficulties students from underrepresented populations face. The authors provide information on how to promote relationships across the institution through an analysis of the critical roles played by parents, peers, faculty members, and others in higher education. The case study and guiding questions help readers understand how to foster a sense of belonging at multiple levels.