scholarly journals Integrated treatment of first-episode psychosis: effect of treatment on family burden

2005 ◽  
Vol 187 (S48) ◽  
pp. s85-s90 ◽  
Author(s):  
Pia Jeppesen ◽  
Lone Petersen ◽  
Anne Thorup ◽  
Maj-Britt Abel ◽  
Johan ⊘ehlenschlæger ◽  
...  

BackgroundThe families of patients with first-episode psychosis often play a major role in care and often experience lack of support.AimsTo determine the effect of integrated treatment v. standard treatment on subjective burden of illness, expressed emotion (EE), knowledge of illness and satisfaction with treatment in key relatives of patients with a first episode of schizophrenia-spectrum disorder.MethodPatients with ICD-10 schizophrenia-spectrum disorders (first episode) were randomly assigned to integrated treatment or to standard treatment. Integrated treatment consisted of assertive community treatment, psychoeducational multi-family groups and social skills training. Key relatives were assessed with the Social Behaviour Assessment Schedule (SBAS, burden of illness), the 5-min speech sample (EE), and a multiple choice questionnaire at entry and after 1 year.ResultsRelatives in integrated treatment felt less burdened and were significantly more satisfied with treatment than relatives in standard treatment. There were no significant effects of intervention groups on knowledge of illness and EE.ConclusionsThe integrated treatment reduced family burden of illness and improved satisfaction with treatment.

2007 ◽  
Vol 22 ◽  
pp. S84 ◽  
Author(s):  
M. Nordentoft ◽  
M. Bertelsen ◽  
A. Thorup ◽  
L. Petersen ◽  
J. Ahlenschleger ◽  
...  

2005 ◽  
Vol 187 (S48) ◽  
pp. s98-s103 ◽  
Author(s):  
Lone Petersen ◽  
Merete Nordentoft ◽  
Pia Jeppesen ◽  
Johan ⊘hlenschlæger ◽  
Anne Thorup ◽  
...  

BackgroundBecause early illness course and outcome may affect the long-term outcome of schizophrenia-spectrum disorders, it is especially important to address poor outcome in this early critical period.AimsTo evaluate whether integrated treatment compared with standard treatment reduced the proportion of patients with poor clinical and social outcome after 1 year.MethodA total of 547 patients with first-episode psychosis were included in the study, 275 randomly assigned to integrated treatment and 272 to standard treatment. Measures assessed psychotic symptoms and social functioning.ResultsThere was a significant beneficial effect of integrated treatment v. standard treatment on ‘any poor outcome’. Integrated treatment had a significantly better effect on ‘any poor outcome’ in patients with schizophrenia compared with patients in standard treatment.ConclusionsThe integrated treatment significantly reduced the proportion of patients with poor clinical and social outcome compared with standard treatment.


2017 ◽  
Vol 8 ◽  
Author(s):  
Mirella Ruggeri ◽  
Antonio Lasalvia ◽  
Paolo Santonastaso ◽  
Francesca Pileggi ◽  
Emanuela Leuci ◽  
...  

2005 ◽  
Vol 79 (1) ◽  
pp. 95-105 ◽  
Author(s):  
A. Thorup ◽  
L. Petersen ◽  
P. Jeppesen ◽  
J. Øhlenschlæger ◽  
T. Christensen ◽  
...  

2016 ◽  
Vol 12 (5) ◽  
pp. 863-868 ◽  
Author(s):  
Yarissa Herman ◽  
Huma Shireen ◽  
Sarah Bromley ◽  
Natalie Yiu ◽  
Eric Granholm

2010 ◽  
Vol 40 (10) ◽  
pp. 1619-1626 ◽  
Author(s):  
M. Nordentoft ◽  
J. Øhlenschlæger ◽  
A. Thorup ◽  
L. Petersen ◽  
Pia Jeppesen ◽  
...  

BackgroundThe effects of hospital-based rehabilitation including weekly supportive psychodynamic therapy compared with specialized assertive intervention and standard treatment has not previously been investigated in first-episode psychosis. The aim of the study was to examine long-term effect on use of institutional care of different intensive interventions for patients with first-episode schizophrenia spectrum disorder on use of psychiatric bed days and days in supported housing.MethodA total of 94 severely ill patients with first-episode schizophrenia spectrum disorders were included in a special part of the Copenhagen OPUS trial and randomized to either the specialized assertive intervention program (OPUS), standard treatment or hospital-based rehabilitation.ResultsIt was a stable pattern that patients randomized to hospital-based rehabilitation spent more days in psychiatric wards and in supported housing throughout the 5-year follow-up period compared with the two other groups. Patients in OPUS treatment spent significantly fewer days in psychiatric wards and supported housing in the first 3 years compared with patients in hospital-based rehabilitation. Due to attrition and small sample size, differences in level of psychotic and negative symptoms at 5-year follow-up could not be evaluated.ConclusionsThe study indicates that hospital-based rehabilitation together with weekly supportive psychodynamic therapy was associated with a continued increased use of psychiatric bed days and days in supported housing. The data cannot justify using hospital-based rehabilitation in first-episode psychosis.


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