The Relative Importance of Hereditary Factors in Manic-Depressive Psychosis and Involutional Melancholia. (Journ. of Nerv. and Ment. Dis., April, 1930.) Farr, C. B., Sloane, P., and Smith, L. H.)

1930 ◽  
Vol 76 (315) ◽  
pp. 849-849
Author(s):  
G. W. T. H. Fleming
1964 ◽  
Vol 110 (465) ◽  
pp. 244-254 ◽  
Author(s):  
G. Hopkinson

The genetic evidence concerning affective illness of later life is still conflicting and the relationship of such conditions to the manic-depressive psychosis unclear. Kallman (1955) believed that, genetically, involutional melancholia bore a closer relationship to schizophrenia than to the manic-depressive psychosis. An increased risk for schizophrenia amongst the relatives of such patients was not observed by Kay (1959) and Stenstedt (1952). Both these writers do however describe a lower loading for manic-depressive psychosis than would be found amongst the relations of manic-depressive patients, though a much higher incidence than in the general population. Both Stenstedt and Kay assumed that they were dealing with a heterogeneous group of patients containing both psychotic and neurotic depressions.


1940 ◽  
Vol 86 (365) ◽  
pp. 1065-1077 ◽  
Author(s):  
R. E. Hemphill ◽  
Max Reiss

The question whether involutional melancholia in females can be regarded as distinct form of mental illness representing a reaction to bodily changes following the menopause has been amply discussed. It has been held by some that such a melancholia is no more than one phase of the manic-depressive psychosis (1, 2). Others hold the opposite view and justify it on statistical and clinical grounds (3).


1963 ◽  
Vol 109 (461) ◽  
pp. 464-469 ◽  
Author(s):  
A. F. da Fonseca

Since its first formulation, the concept of manic-depressive illness has been subject to successive modification and, on the whole, to progressive enlargement. It was Kraepelin, following on the attempts of Baillarger, Falret and Magnan, who grouped together all the various nosographic forms distinguished by isolated depressive or manic crises, periodic or alternating (and even the form designated as involutional melancholia), including them all under the sole class name of manic-depressive psychosis. The morbid entity thus defined was regarded as distinguished by the periodicity of the crises, each with a tendency towards social remission. Aetiologically the causation was seen as preponderantly hereditary.


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