Selection of Patients for Surgery After Induction Chemotherapy for N2 Non–Small-Cell Lung Cancer

2006 ◽  
Vol 24 (21) ◽  
pp. 3317-3318 ◽  
Author(s):  
Peter Goldstraw
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Induction Chemotherapy ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Selection Of Patients ◽  
Selection Of

scholarly journals The Reproducibility of the Immunohistochemical PD-L1 Testing in Non-Small-Cell Lung Cancer: A Multicentric Italian Experience

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Elena Vigliar ◽  
Umberto Malapelle ◽  
Francesca Bono ◽  
Nicola Fusco ◽  
Diego Cortinovis ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Checkpoint Inhibitors ◽  
Small Cell ◽  
Small Cell Lung ◽  
Italian Experience ◽  
Programmed Death ◽  
Selection Of Patients ◽  
Selection Of

An important harmonization effort was produced by the scientific community to standardize both the preanalytical and interpretative phases of programmed death-ligand 1 (PD-L1) immunohistochemical (IHC) testing in non-small-cell lung cancer (NSCLC). This analysis is crucial for the selection of patients with advanced-stage tumors eligible for treatment with pembrolizumab and potentially with other anti-PD-1/PD-L1 checkpoint inhibitors. This multicentric retrospective study evaluated the reproducibility of PD-L1 testing in the Italian scenario both for closed and open platforms. In the evaluation of the well-known gold-standard combinations (Agilent 22C3 PharmDx on Dako Autostainer versus Roche’s Ventana SP263 on BenchMark), the results confirmed the literature data and showed complete overlapping between the two methods. With regard to the performances by using open platforms, the combination of 22C3 with Dako Omnis or Benchmark obtained good results basically, while the 28,8 clone seemed to be associated with worse scores.

Consolidative thoracic radiotherapy in stage IV small cell lung cancer: Selection of patients amongst European IASLC and ESTRO experts

2019 ◽  
Vol 135 ◽  
pp. 74-77 ◽  
Author(s):  
Paul Martin Putora ◽  
Markus Glatzer ◽  
Dirk De Ruysscher ◽  
Corinne Faivre-Finn ◽  
José Belderbos ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Stage Iv ◽  
Small Cell ◽  
Thoracic Radiotherapy ◽  
Small Cell Lung ◽  
Selection Of Patients ◽  
Selection Of

Morbidity and Mortality after Induction Chemotherapy Followed by Surgery in IIIa-N2 non Small Cell Lung Cancer

2009 ◽  
Vol 109 (3) ◽  
pp. 333-339 ◽  
Author(s):  
Ph. Borreman ◽  
P. De Leyn ◽  
H. Decaluwé ◽  
J. Moons ◽  
D. Van Raemdonck ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Induction Chemotherapy ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Morbidity And Mortality ◽  
Small Cell Lung
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