Identification and functional characterization of a long non-coding RNA driving hormone-independent prostate cancer progression.

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. 11087-11087
Author(s):  
Francesco Crea ◽  
Abhijit Parolia ◽  
Hui Xue ◽  
Paolo Frumento ◽  
Yuwei Wang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Progression ◽  
Functional Characterization ◽  
Prostate Cancer Progression ◽  
Non Coding Rna ◽  
Long Non Coding Rna

scholarly journals The mitotic regulator Hec1 is a critical modulator of prostate cancer through the long non-coding RNA BX647187 in vitro

2015 ◽  
Vol 35 (6) ◽  
Author(s):  
Haifeng Wang ◽  
Xu Gao ◽  
Xin Lu ◽  
Yan Wang ◽  
Chunfei Ma ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Molecular Mechanism ◽  
Cancer Progression ◽  
Nuclear Division ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Prostate Cancer Progression ◽  
Non Coding Rna ◽  
Long Non Coding Rna

The mitotic regulator Hec1 (highly expressed in cancer), is a member of a conserved Ndc80 (nuclear division cycle 80) complex that regulates mitotic processes. We find that Hec1 is consistently overexpressed in human prostate cancer and Hec1 is closely linked with human prostate cancer progression through the meditator LncRNA BX647187. Our studies may contribute to understand the molecular mechanism of PCa pathogenesis and clinical therapy.

Abstract LB-474: Estrogen receptor regulated long non coding RNA: An evolving paradigm in prostate cancer progression

2012 ◽  
Author(s):  
Dimple Chakravarty ◽  
Andrea Sboner ◽  
Eugenia Giannopoulou ◽  
Olivier Elemento ◽  
Archa Fox ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Estrogen Receptor ◽  
Cancer Progression ◽  
Prostate Cancer Progression ◽  
Non Coding Rna ◽  
Long Non Coding Rna

Abstract 2549: A long non-coding RNA regulates the androgen receptor and mediates prostate cancer progression

2017 ◽  
Author(s):  
Sethuramasundaram Pitchiaya ◽  
Rohit Malik ◽  
Marcin Cieslik ◽  
Yajia Zhang ◽  
Xia Jiang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Cancer Progression ◽  
Prostate Cancer Progression ◽  
Non Coding Rna ◽  
Long Non Coding Rna

scholarly journals The Long Non-Coding RNA IDH1-AS1 Promotes Prostate Cancer Progression by Enhancing IDH1 Enzyme Activity

2020 ◽  
Vol Volume 13 ◽  
pp. 7897-7906
Author(s):  
Shuo Wu ◽  
Liucheng Ding ◽  
Hewei Xu ◽  
Jie Gao ◽  
Yunpeng Shao ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Enzyme Activity ◽  
Cancer Progression ◽  
Prostate Cancer Progression ◽  
Non Coding Rna ◽  
Long Non Coding Rna
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