scholarly journals Systematic Review of Healthcare Economic Evaluation on Malaysia: An Overview on Cancer-Related Economic Studies

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 76s-76s
Author(s):  
K.N. Ku Abdul Rahim ◽  
K. Hanin Farhana
Keyword(s):  
Systematic Review ◽  
Cervical Cancer ◽  
Health Economic ◽  
Economic Evaluation ◽  
Full Text ◽  
Evaluation Studies ◽  
Hpv Vaccination ◽  
Data Retrieval ◽  
Economic Studies

Background: In Malaysia, the inclusion of health economic evidence in health technology assessment improves the efficiency of the healthcare spending as it is used to promote the use of value for money in policy making. However, despite the potential of its use in ensuring the value of health technologies, its adoption is constrained by several factors. Limited number of researchers to produce economic evaluation, challenges in local data retrieval and lack of awareness and understanding of value-based concept among decision makers are among the most common limiting factors in Malaysia. Aim: To conduct a systematic review of economic evaluation studies in Malaysia and to explore and describe cancer-related economic evaluation studies in Malaysia. Methods: A comprehensive scientific electronic databases was conducted and the last search was done on 20 March 2017. Additional articles were identified from reviewing the references of retrieved articles and personal communication with the local higher institution representatives. Only full text of full and partial economic evaluations conducted in Malaysia were considered to be eligible for the review. Data extraction was performed by first author and verified by second author. Critical Appraisal Skills Program (CASP) checklist and Quality of Health Economic Studies (QHES) instrument was used as the quality appraisal tools in view of variability of the quality of conduct and reporting of economic evaluation. Results: Based on the evidence search, 1014 titles were retrieved from the scientific electronic databases. After articles selection, 39 full text articles were finally selected to be included in this review. Of these, eight studies (20.5%) are cancer-related economic evaluation. Five cost-utility analyses, two cost-effectiveness analyses and one cost-minimization analysis were conducted in Malaysia up to March 20, 2017. The studies are on HPV vaccination in preventing cervical cancer, early screening of cervical cancer, treatment using monoclonal antibody for colorectal cancer, targeted therapy in HER2+ breast cancer and antiemetic in chemotherapy induced nausea and vomiting. Among the interventions that were highly cost effective were screening strategies and HPV vaccination in prevention of cervical cancer as well as additional of granisetron as antiemetic regimens for chemotherapy-induced emesis. Conclusion: This review provides useful information on the overall scenario of economic evaluation in Malaysia, particularly on cancer which incur high financial impact to the healthcare system. Various type of analysis has been conducted in recent years which provide different findings and information such as the incremental value, local costs data, patient preference and economic burden. These information may be adopted by other researchers in conducting future economic evaluation by facilitating and accelerating the process of producing the evaluation.

scholarly journals A Systematic Review of Scope and Quality of Health Economic Evaluation Studies in Vietnam

PLoS ONE ◽  
2014 ◽  
Vol 9 (8) ◽  
pp. e103825 ◽  
Author(s):  
Bach Xuan Tran ◽  
Vuong Minh Nong ◽  
Rachel Marie Maher ◽  
Phuong Khanh Nguyen ◽  
Hoat Ngoc Luu
Keyword(s):  
Systematic Review ◽  
Health Economic ◽  
Economic Evaluation ◽  
Evaluation Studies ◽  
Health Economic Evaluation

Systematic review of health economic evaluation studies of dengue vaccines

Vaccine ◽  
2019 ◽  
Vol 37 (17) ◽  
pp. 2298-2310 ◽  
Author(s):  
Patrícia Coelho de Soárez ◽  
Aline Blumer Silva ◽  
Bruno Azevedo Randi ◽  
Laura Marques Azevedo ◽  
Hillegonda Maria Dutilh Novaes ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Economic ◽  
Economic Evaluation ◽  
Evaluation Studies ◽  
Health Economic Evaluation

scholarly journals A SYSTEMATIC REVIEW OF HEPATITIS VIRUS REVIEW STUDIES: A CASE OF HEALTH ECONOMIC EVALUATION ANALYSIS

2017 ◽  
Vol 9 (5) ◽  
pp. 114
Author(s):  
Phuong Hong Le ◽  
Quang Vinh Tran ◽  
Trung Quang Vo
Keyword(s):  
Systematic Review ◽  
Health Economic ◽  
Economic Evaluation ◽  
Systematic Reviews ◽  
Hepatitis Virus ◽  
Health Economic Evaluation ◽  
Current Evidence ◽  
Inclusion Criteria ◽  
Publication Period

Objective: Systematic reviews of economic analysis are necessary for assessing reports and making a decision. A systematic review of systematic reviews is mean of summarizing the current evidence across specialties of the same or very similar intervention, to provide a synthesis treatment effect. The aim of this study was to explore and to assess the quality of systematic reviews conducted hepatitis economic evaluation.Methods: This study was designed as a systematic review following the AMSTAR guideline through Medline, Cochrane, and Science Direct databases. It was scoped in publication period of 2001 and 2016 in international journals. The quality assessment of the included studies was based on AMSTAR checklist. Two authors did the appreciation independently and all the different results were solved by discussion to give the conclusion.Results: 851 publications found, only 25 studies of those met the inclusion criteria. These studies consisted of 5 studies for vaccination and 20 for non-vaccination. There were only 16% (n=4) based on PRISMA guideline; and twenty-one studies (64%) were not showing about the method of the systematic review or not based on any guideline. Only three articles has published in 2016 with a high standard.Conclusion: According to the results of the appraisal AMSTAR checklist, this review shows clearly the current situation and an urgent need for an increase of quality of hepatitis virus review studies based on health economic evaluation.

scholarly journals The health-economic studies of HPV vaccination in Southeast Asian countries: a systematic review

2017 ◽  
Vol 16 (9) ◽  
pp. 933-943 ◽  
Author(s):  
Didik Setiawan ◽  
Monika Puri Oktora ◽  
Raymond Hutubessy ◽  
Arthorn Riewpaiboon ◽  
Maarten J. Postma
Keyword(s):  
Systematic Review ◽  
Health Economic ◽  
Hpv Vaccination ◽  
Southeast Asian ◽  
Asian Countries ◽  
Southeast Asian Countries ◽  
Economic Studies

scholarly journals Can polygenic risk scores contribute to cost-effective cancer screening? A systematic review

2021 ◽  
Author(s):  
Padraig Dixon ◽  
Edna Keeney ◽  
Jenny C Taylor ◽  
Sarah Wordsworth ◽  
Richard Martin
Keyword(s):  
Systematic Review ◽  
Health Economic ◽  
Cost Effectiveness ◽  
Cancer Screening ◽  
Cost Effective ◽  
Risk Scores ◽  
Polygenic Risk ◽  
The Cost ◽  
Economic Studies

Polygenic risk is known to influence susceptibility to cancer. The use of data on polygenic risk, in conjunction with other predictors of future disease status, may offer significant potential for preventative care through risk-stratified screening programmes. An important element in the evaluation of screening programmes is their cost-effectiveness. We undertook a systematic review of papers evaluating the cost-effectiveness of screening interventions informed by polygenic risk scores compared to more conventional screening modalities. We included papers reporting cost-effectiveness outcomes in the English language published as articles or uploaded onto preprint servers with no restriction on date, type of cancer or form of polygenic risk modelled. We excluded papers evaluating screening interventions that did not report cost-effectiveness outcomes or which had a focus on monogenic risk. We evaluated studies using the Quality of Health Economic Studies checklist. Ten studies were included in the review, which investigated three cancers: prostate (n=5), colorectal (n=3) and breast (n=2). All study designs were cost-utility papers implemented as Markov models (n=6) or microsimulations (n=4). Nine of ten papers scored highly (score >75 on a 0-100) scale) when assessed using the Quality of Health Economic Studies checklist. Eight of ten studies concluded that polygenic risk informed cancer screening was likely to be more cost-effective than alternatives. However, the included studies lacked robust external data on the cost of polygenic risk stratification, did not account for how very large volumes of polygenic risk data on individuals would be collected and used, did not consider ancestry-related differences in polygenic risk, and did not fully account for downstream economic sequalae stemming from the use of polygenic risk data in these ways. These topics merit attention in future research on how polygenic risk data might contribute to cost-effective cancer screening.

Quality of economic evaluations of ventricular assist devices: A systematic review

2020 ◽  
Vol 36 (4) ◽  
pp. 380-387
Author(s):  
Sarah Fontenay ◽  
Lionel Catarino ◽  
Soumeya Snoussi ◽  
Hélène van den Brink ◽  
Judith Pineau ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Economic ◽  
Economic Evaluation ◽  
Cost Effectiveness ◽  
Health Economic Evaluation ◽  
Ventricular Assist Devices ◽  
Economic Evaluations ◽  
Level Of Evidence ◽  
Ventricular Assist

ObjectiveBecause of a lack of suitable heart donors, alternatives to transplantation are required. These alternatives can have high costs. The aim of this study was to perform a systematic review of cost-effectiveness studies of ventricular assist devices (VADs) and to assess the level of evidence of relevant studies. The purpose was not to present economic findings.MethodsA systematic review was performed using four electronic databases to identify health economic evaluation studies dealing with VADs. The methodological quality and reporting quality of the studies was assessed using three different tools, the Drummond, Cooper, and CHEERS (Consolidated Health Economic Evaluation Reporting Standards) checklists.ResultsOf the 1,258 publications identified, thirteen articles were included in this review. Twelve studies were cost–utility analyses and one was a cost-effectiveness analysis. According to the Cooper hierarchy scale, the quality of the data used was heterogeneous. The level of evidence used for clinical effect sizes, safety data, and baseline clinical data was of poor quality. In contrast, cost data were of high quality in most studies. Quality of reporting varied between studies, with an average score of 17.4 (range 15–19) according to the CHEERS checklist.ConclusionThe current study shows that the quality of clinical data used in economic evaluations of VADs is rather poor in general. This is a concern that deserves greater attention in the process of health technology assessment of medical devices.

scholarly journals Systematic Review of Health Economic Evaluation Studies Developed in Brazil from 1980 to 2013

2018 ◽  
Vol 6 ◽  
Author(s):  
Tassia Cristina Decimoni ◽  
Roseli Leandro ◽  
Luciana Martins Rozman ◽  
Dawn Craig ◽  
Cynthia P. Iglesias ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Economic ◽  
Economic Evaluation ◽  
Evaluation Studies ◽  
Health Economic Evaluation

Cost-Utility Analyses in US Orthopaedic Foot and Ankle Surgery: A Systematic Review

2018 ◽  
Vol 11 (6) ◽  
pp. 548-552 ◽  
Author(s):  
Aditya V. Karhade ◽  
John Y. Kwon
Keyword(s):  
Systematic Review ◽  
Health Economic ◽  
Cost Effective ◽  
The United States ◽  
Cost Utility ◽  
Ankle Fractures ◽  
Foot And Ankle ◽  
End Stage ◽  
Economic Studies

Background. While investigations have been performed examining the quality of US-based cost-utility analyses for other orthopaedic subspecialties and have provided important insights, a similar analysis has not been performed examining the foot and ankle literature. Methods. A systematic review of foot and ankle studies was conducted to identify cost-utility analyses published between 2000 and 2017. Of 687 studies screened by abstract, 4 cost-utility studies were identified and scored by the Quality of Health Economic Studies instrument. Results. Of these 4 studies, 3 examined end-stage arthritis and 1 examined unstable ankle fractures. Cost-effective interventions identified by these studies included the performance of total ankle arthroplasty over ankle arthrodesis or nonoperative treatment for end-stage arthritis and suture button fixation over syndesmotic screws for unstable supination–external rotation ankle fractures. The mean Quality of Health Economic Studies scores for these studies was 87.5. Conclusion. Despite the increasing focus on value-based care delivery in the United States, there are few foot and ankle cost-utility analyses. Nonetheless, the quality of existing analyses is high. Certain interventions have been identified as cost-effective as highlighted above and the findings of this review can be used to help design future analyses in order to best demonstrate the cost-effectiveness of foot and ankle interventions. Levels of Evidence: Level III: Systematic Review of level III studies

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