Organizational Principles of Cerebellar Cortical Systems

2021 ◽  
pp. 15-34
Author(s):  
D. E. Haines
Keyword(s):  
Organizational Principles

Nature, poetry and medicine in late 18th century England: a unified perspective of Erasmus Darwin

1976 ◽  
Vol 7 (4) ◽  
pp. 537-537
Author(s):  
M. McNEIL
Keyword(s):  
18Th Century ◽  
Human Society ◽  
Nature Poetry ◽  
Medicine And Philosophy ◽  
Late 18Th Century ◽  
Medical Theory ◽  
Lunar Society Of Birmingham ◽  
Organizational Principles ◽  
Century Science ◽  
Erasmus Darwin

Erasmus Darwin was the focus and embodiment of provincial England in his day. Renowned as a physician, he spent much of his life at Lichfield. He instigated the founding of the Lichfield Botanic Society, which provided the first English translation of the works of Linnaeus, and established a botanic garden; the Lunar Society of Birmingham; the Derby Philosophical Society; and two provincial libraries. A list of Darwin's correspondents and associates reads like a "who's who" of eighteenth century science, industry, medicine and philosophy. His poetry was also well received by his contemporaries and he expounded the evolutionary principles of life. Darwin can be seen as an English equivalent of Lamarck, being a philosopher of nature and human society. His ideas have been linked to a multitude of movements, including the nosological movement in Western medicine, nineteenth century utilitarianism, Romanticism in both Britain and Germany, and associationist psychology. The relationships between various aspects of Darwin's interests and the organizational principles of his writings were examined. His poetical form and medical theory were not peripheral to his study of nature but intrinsically linked in providing his contemporaries with a panorama of nature. A richer, more integrated comprehension of Erasmus Darwin as one of the most significant and representative personalities of his era was presented.

Levels of modeling of mechanisms of visually guided behavior

1987 ◽  
Vol 10 (3) ◽  
pp. 407-436 ◽  
Author(s):  
Michael A. Arbib
Keyword(s):  
Neural Circuits ◽  
Neural Circuitry ◽  
Learning Approach ◽  
Visually Guided ◽  
Visuomotor Coordination ◽  
Prey Recognition ◽  
High Level ◽  
Organizational Principles ◽  
Different Levels ◽  
Dextrous Hands

AbstractIntermediate constructs are required as bridges between complex behaviors and realistic models of neural circuitry. For cognitive scientists in general, schemas are the appropriate functional units; brain theorists can work with neural layers as units intermediate between structures subserving schemas and small neural circuits.After an account of different levels of analysis, we describe visuomotor coordination in terms of perceptual schemas and motor schemas. The interest of schemas to cognitive science in general is illustrated with the example of perceptual schemas in high-level vision and motor schemas in the control of dextrous hands.Rana computatrix, the computational frog, is introduced to show how one constructs an evolving set of model families to mediate flexible cooperation between theory and experiment. Rana computatrix may be able to do for the study of the organizational principles of neural circuitry what Aplysia has done for the study of subcellular mechanisms of learning. Approach, avoidance, and detour behavior in frogs and toads are analyzed in terms of interacting schemas. Facilitation and prey recognition are implemented as tectal-pretectal interactions, with the tectum modeled by an array of tectal columns. We show how layered neural computation enters into models of stereopsis and how depth schemas may involve the interaction of accommodation and binocular cues in anurans.

scholarly journals Organizational principles of 3D genome architecture

2018 ◽  
Vol 19 (12) ◽  
pp. 789-800 ◽  
Author(s):  
M. Jordan Rowley ◽  
Victor G. Corces
Keyword(s):  
Genome Architecture ◽  
3D Genome ◽  
Organizational Principles

scholarly journals Organization Life Cycle and the Inversive Relationship

2017 ◽  
Vol 6 (2) ◽  
pp. 53-59
Author(s):  
Севостьянов ◽  
D. Sevostyanov
Keyword(s):  
Life Cycle ◽  
Life Cycle Analysis ◽  
Comparative Assessment ◽  
Organizational Life ◽  
Organizational Life Cycle ◽  
Internal Contradiction ◽  
Organization Life Cycle ◽  
Organizational Principles

This article analyzes the manifestation of the inversive relationship in the life cycle of the organization. Inversion is an internal contradiction in the hierarchy between the position of the hierarchical element, and its role. The reason for inversions is the discrepancy between the orientation of the organizational principles of hierarchy. The development of inversive relations leads the organization toward completion of its life cycle. Analysis of the inversive relationship in the hierarchy allows the comparative assessment of different models of the organizational life cycle.

scholarly journals Cell Tracking for Organoids: Lessons From Developmental Biology

2021 ◽  
Vol 9 ◽  
Author(s):  
Max A. Betjes ◽  
Xuan Zheng ◽  
Rutger N. U. Kok ◽  
Jeroen S. van Zon ◽  
Sander J. Tans
Keyword(s):  
Cell Tracking ◽  
Cellular Level ◽  
Model Systems ◽  
Great Promise ◽  
Cellular Processes ◽  
The Past ◽  
Fluorescent Markers ◽  
Lineage Trees ◽  
Microscopy Techniques ◽  
Organizational Principles

Organoids have emerged as powerful model systems to study organ development and regeneration at the cellular level. Recently developed microscopy techniques that track individual cells through space and time hold great promise to elucidate the organizational principles of organs and organoids. Applied extensively in the past decade to embryo development and 2D cell cultures, cell tracking can reveal the cellular lineage trees, proliferation rates, and their spatial distributions, while fluorescent markers indicate differentiation events and other cellular processes. Here, we review a number of recent studies that exemplify the power of this approach, and illustrate its potential to organoid research. We will discuss promising future routes, and the key technical challenges that need to be overcome to apply cell tracking techniques to organoid biology.

scholarly journals The challenges of instructing health professional according to organizational principles and basis of PSF in Brazil

2007 ◽  
Vol 1 (1) ◽  
pp. 32
Author(s):  
Marco Aurélio Da Ros ◽  
Cecília Marin
Keyword(s):  
Health Professional ◽  
Organizational Principles

No principio e no fim, falamos é do Sistema Único de saúde (SUS). PSF é só uma parte que vem a ajudar a construí-lo. E antes do SUS, há uma história a ser contada. Porque sem ela não se pode entender a magnitude do desafio que se tem pela frente e a ruptura epistemológica1 que precisamos fazer para construir o novo na saúde, e dentro desse desafio uma das estratégias adotadas é o PSF. Dizer que temos heranças flexnerianas, que temos idéias corporativas, que a mídia não diz nada de bom do SUS, que a população não conhece o SUS/PSF é, até certo ponto, óbvio. Mas, para entendermos o significado e a ousadia de colocar numa constituição que saúde é direito de todos, dever do Estado2 – e a partir daí lutar para viabilizar o inscrito, e montar uma estratégia para tal (uma delas o PSF) –, devemos nos reportar ao século XIX, conforme relata Rosen em seu livro Da Política Médica à Medicina Social3. É de lá que vem a herança progressista do Movimento para Reforma Sanitária, o protagonista da construção do SUS e do próprio PSF.

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