The Chemical Work of Biosynthesis

2019 ◽  
pp. 274-286
Author(s):  
Jean-Louis Burgot
Keyword(s):  
1882 ◽  
Vol 14 (347supp) ◽  
pp. 5539-5540
Author(s):  
D. Tommasi
Keyword(s):  

It might be supposed that the discovery of a chemical element was a reason ably straightforward historical event which could be described in a few pages. Indeed in his biography of William Crookes (1), E. E. F. D ’Albe describes Crookes’s 1861 discovery o f thallium in just under six pages (2). Yet if we simply consider the science which was involved in Crookes’s work on thallium a complex series of events emerge. The presence of thallium had first to be detected, next a chemical process was undertaken to verify its elemental nature and finally a quantity of the pure element had to be isolated. In the 1860s there was no generally agreed definition of what constituted the discovery of a chemical element — detection, verification or isolation. But in the case of thallium individuals often argued strongly for one of these definitions. Such individual choices were not arbitrary, but were directed, as we shall see, towards serving their interests. To understand their choices, therefore, we cannot simply consider only the science, when discussing the discovery of thallium, but we also have to examine and define the context in which work on thallium was conducted.


Bothalia ◽  
1994 ◽  
Vol 24 (2) ◽  
pp. 171-185 ◽  
Author(s):  
A. Louise Schutte

An overview is given of literature concerning the genus Aspergillus Link and its teleomorphs.  Chaetosartorya Subram.. Emericellu Berk. Broome.  Eurotium Link.  Fennellia B.J. Wiley E.G. Simmons,  Neosartorya Malloch Cain and Sclerocleista Subram. encountered in the Republic of South Africa. Botswana. Lesotho. Mozambique. Namibia. Swaziland. Transkei and Zimbabwe up to 1993. The information is grouped under headings that indicate the field of research, namely general mycology, plant pathology, human pathology, animal and insect pathology, industrial relevance and secondary metabolites and mycotoxins. An alphabetical list of recorded Aspergillus species is provided and the relevant host or substrate is given together with a literature reference, while the fungal nomenclature has been updated. All the  Aspergillus species that are regarded as common have been reported from southern Africa. No in-depth research has been done here on this group, except for chemical work on mycotoxins.


Bothalia ◽  
1992 ◽  
Vol 22 (1) ◽  
pp. 77-91 ◽  
Author(s):  
A. L. Schutte

Literature on the hyphomycete genus Penicillium Link and its teleomorphs, Eupenicillium Ludwig and  Talaromyces C.R.Benjamin, is surveyed in the Republic of South Africa, Lesotho, Mozambique, Namibia, Swaziland and Transkei up to 1990. References are grouped under the headings, general mycology, plant pathology, industrial application, medical importance, mycotoxins and chemical work. An alphabetical list of the species recorded in southern Africa as well as the host and/or substrate from which each species has been reported is presented with relevant literature references; specimens in various culture collections are also incorporated. Although most of the known Penicillium species have already been reported from southern Africa, in-depth work is still required in all fields of research concerning this genus.


1986 ◽  
Vol 50 (357) ◽  
pp. 375-384 ◽  
Author(s):  
John Ridley

AbstractA proportion of the heat added to a body of rock during prograde metamorphism will be absorbed in the chemical work of metamorphic recrystallization. When and where heat is so absorbed will affect the exact thermal histories of the rocks, and hence the metamorphic textures. This paper reports the results of modelling of the inter-relations between reaction progress and thermal histories in a rock column. The results suggest that volumes of rock undergoing reaction at any moment act as heat sinks and absorb heat from the surrounding rock, that reaction generally takes place close to the temperature at which nucleation took place, and that steady heating of a rock pile can give rise to a reaction history in which spurts of reaction are separated by ‘quiet’, non-reactive intervals.


The 250th anniversary of the birth of James Watt will be celebrated in January 1986. Watt is primarily remembered for his improvements to the steam engine, which were of such great importance in the early phase of the Industrial Revolution (1). It is less well known that throughout his life Watt was interested in chemistry. This article outlines the main themes of Watt’s chemical work. Watt learned the trade of instrument maker in London. On returning to his native Scotland in 1756 he was employed for a few months by the University of Glasgow in the repair of some astronomical instruments. During this time he met the newly appointed professor of anatomy and chemistry, Joseph Black, who may have assisted Watt in obtaining his appointment as mathematical instrument maker to the University in the following year. It seems possible that Black stimulated Watt’s latent interest in chemistry. Although Watt’s subsequent career took him away from Scotland, he remained in correspondence with Black until the latter’s death in 1799. This correspondence shows how keen and sustained was Watt’s interest in chemistry (2).


1984 ◽  
Vol 17 (1) ◽  
pp. 31-46 ◽  
Author(s):  
H. E. Le Grand

Jean Antoine Claude Chaptal was not only a chemical manufacturer and one of the first ‘industrial scientists’ but was also, according to his own testimony, one of the early supporters of Lavoisier's system of chemistry. It might be assumed that Chaptal's pioneering work in industrial chemistry was intimately linked with his acceptance of the oxygen system of chemistry; more specifically, that this theory served to direct and inform his applied research and contributed not a little to its success. Indeed, he himself in 1790 explicitly stated this to have been the case. A close study of his work prior to 1790 fails, however, to establish the importance of such a linkage. First, his selection of research topics proves to have owed little to the ‘new chemistry’ but much to the scientific and economic milieu of his province of Languedoc and of Montpellier, its administrative seat. Second, the significance of his acceptance of the ‘new chemistry’ appears rather problematic, not the least because of the rather hazy boundaries between the phlogistic and Lavoisian theories in the 1780s. Third, it is not clear from the evidence available how the new theory helped solve the various problems of industrial chemistry he faced, or could have done so, other than to offer alternative explanations for processes with which he was already familiar and indeed had often mastered. It will be suggested that it is precisely this less dramatic role which was filled by the new chemistry: that of ‘rectifying’ his ideas by providing alternative and more satisfactory rationalizations of his experiences and experiments in the laboratory and the factory, not that of enabling him to simplify and perfect old processes nor to invent new ones. To put the point more bluntly: Chaptal's early successes and reputation in industrial chemistry were not a by-product of his allegiance to the new chemistry; rather, his growing adherence to that system was a by-product of its ability to provide satisfactory post-hoc explanations of the chemical processes and products with which he was concerned.


In investigations made by one of us (in collaboration with P. Rothschild (1931)) on the blood content of the canine uterus, difficulties arose in the hæmoglobin determinations owing to the presence of a green pigment in that organ. The other author (Lemberg, 1931) had at the time just investigated the green pigment contained in the egg-shells of many birds and had isolated its methyl-ester in crystalline form; he at once realised that the pigment mentioned above was of the same nature and furnished a profitable field for investigation. We must here thank Professor Keilin for his valuable help in the preliminary stages of the research. There is considerable literature on the subject in papers of Medicine and Anatomy, but so far as modem physiological and biochemical publications are concerned, it has been forgotten, there being no recent chemical work on the subject.


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