Mechanisms of the Mammalian Cell Cytotoxicity of Explosives

2009 ◽  
pp. 239-254
2002 ◽  
Vol 40 (2) ◽  
pp. 134-142 ◽  
Author(s):  
Michael J. Plewa ◽  
Yahya Kargalioglu ◽  
Danielle Vankerk ◽  
Roger A. Minear ◽  
Elizabeth D. Wagner

1973 ◽  
Vol 138 (1) ◽  
pp. 318-323 ◽  
Author(s):  
Paul J. Edelson ◽  
Zanvil A. Cohn

Lactoperoxidase, in the presence of hydrogen peroxide and iodide is cytotoxic for human and mouse lymphoid cells, and human erythrocytes. Myeloperoxidase, in amounts equivalent to 1.5 x 106 neutrophils, readily replaces lactoperoxidase, and allows the substitution of the iodide ion by chloride. The myeloperoxidase-mediated reaction is rapid, and highly efficient, leading to 85–90% cell death in 90 min, as measured by 51chromium release and dye exclusion. The mixture of granulocytes. monocytes, and lymphocytes present in an inflammatory exudate, and the intimate cell-to-cell association characteristic of cytotoxic phenomena may provide the in vivo requirements for such a system.


2012 ◽  
Vol 5 (1) ◽  
pp. 294-298 ◽  
Author(s):  
Juan Fu ◽  
Gaoxiang Rong ◽  
Yan Deng

2009 ◽  
pp. 211-226 ◽  
Author(s):  
Lina Miseviciene ◽  
Zilvinas Anusevicius ◽  
Audrone Maroziene ◽  
Henrikas Nivinskas ◽  
Jonas Sarlauskas ◽  
...  

2016 ◽  
Vol 50 (21) ◽  
pp. 11752-11759 ◽  
Author(s):  
Shengkun Dong ◽  
Jinfeng Lu ◽  
Michael J. Plewa ◽  
Thanh H. Nguyen

2007 ◽  
Vol 78 (6) ◽  
pp. 474-478 ◽  
Author(s):  
S. L. Daniel ◽  
G. L. Hartman ◽  
E. D. Wagner ◽  
M. J. Plewa

2017 ◽  
Vol 4 (11) ◽  
pp. 475-480 ◽  
Author(s):  
Hannah K. Liberatore ◽  
Michael J. Plewa ◽  
Elizabeth D. Wagner ◽  
Jeanne M. VanBriesen ◽  
David B. Burnett ◽  
...  

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