A Role of Functional Brain Asymmetry in Human Adaptation

2006 ◽  
pp. 154-161
Keyword(s):  
Brain Asymmetry ◽  
Human Adaptation ◽  
Functional Brain

scholarly journals The genetic architecture of structural left–right asymmetry of the human brain

2021 ◽  
Author(s):  
Zhiqiang Sha ◽  
Dick Schijven ◽  
Amaia Carrion-Castillo ◽  
Marc Joliot ◽  
Bernard Mazoyer ◽  
...  
Keyword(s):  
Brain Asymmetry ◽  
Functional Enrichment ◽  
Brain Organization ◽  
Genome Wide ◽  
Brain Expression ◽  
Using Data ◽  
Left Right Asymmetry ◽  
The Uk ◽  
Subcortical Volume

AbstractLeft–right hemispheric asymmetry is an important aspect of healthy brain organization for many functions including language, and it can be altered in cognitive and psychiatric disorders. No mechanism has yet been identified for establishing the human brain’s left–right axis. We performed multivariate genome-wide association scanning of cortical regional surface area and thickness asymmetries, and subcortical volume asymmetries, using data from 32,256 participants from the UK Biobank. There were 21 significant loci associated with different aspects of brain asymmetry, with functional enrichment involving microtubule-related genes and embryonic brain expression. These findings are consistent with a known role of the cytoskeleton in left–right axis determination in other organs of invertebrates and frogs. Genetic variants associated with brain asymmetry overlapped with those associated with autism, educational attainment and schizophrenia. Comparably large datasets will likely be required in future studies, to replicate and further clarify the associations of microtubule-related genes with variation in brain asymmetry, behavioural and psychiatric traits.

Brain asymmetry, immunity, handedness

Open Medicine ◽  
2012 ◽  
Vol 7 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Zlatislav Stoyanov ◽  
Lyoubka Decheva ◽  
Irina Pashalieva ◽  
Piareta Nikolova
Keyword(s):  
Immune Response ◽  
Human Brain ◽  
Right Hemisphere ◽  
Functional Organization ◽  
Brain Asymmetry ◽  
Internal Environment ◽  
Living Nature ◽  
Left Right Asymmetry ◽  
The Right

AbstractThe principle of symmetry-asymmetry is widely presented in the structural and functional organization of the nonliving and living nature. One of the most complex manifestations of this principle is the left-right asymmetry of the human brain. The present review summarizes previous and contemporary literary data regarding the role of brain asymmetry in neuroimmunomodulation. Some handedness-related peculiarities are outlined additionally. Brain asymmetry is considered to be imprinted in the formation and regulation of the individual’s responses and relationships at an immunological level with the external and internal environment. The assumptions that the hemispheres modulate immune response in an asymmetric manner have been confirmed in experiments on animals. Some authors assume that the right hemisphere plays an indirect role in neuroimmunomodulation, controlling and suppressing the left hemispheric inductive signals.

scholarly journals The role of nitrogen oxides in human adaptation to hypoxia

2011 ◽  
Vol 1 (1) ◽  
Author(s):  
Denny Z. Levett ◽  
◽  
Bernadette O. Fernandez ◽  
Heather L. Riley ◽  
Daniel S. Martin ◽  
...  
Keyword(s):  
Nitrogen Oxides ◽  
Adaptation To Hypoxia ◽  
Human Adaptation

Functional brain asymmetry in adult novelty response: On fluidity of neonatal novelty exposure effects

2011 ◽  
Vol 221 (1) ◽  
pp. 91-97 ◽  
Author(s):  
Akaysha C. Tang ◽  
Bethany Reeb-Sutherland ◽  
Zhen Yang
Keyword(s):  
Brain Asymmetry ◽  
Functional Brain ◽  
Novelty Response

scholarly journals Multiplex core–periphery organization of the human connectome

2018 ◽  
Vol 15 (146) ◽  
pp. 20180514 ◽  
Author(s):  
Federico Battiston ◽  
Jeremy Guillon ◽  
Mario Chavez ◽  
Vito Latora ◽  
Fabrizio De Vico Fallani
Keyword(s):  
General Framework ◽  
Brain Networks ◽  
Fundamental Question ◽  
Brain Functioning ◽  
Functional Brain ◽  
Functional Interactions ◽  
The Core ◽  
Connectivity Patterns ◽  
Functional Brain Networks

What is the core of the human brain is a fundamental question that has been mainly addressed by studying the anatomical connections between differently specialized areas, thus neglecting the possible contributions from their functional interactions. While many methods are available to identify the core of a network when connections between nodes are all of the same type, a principled approach to define the core when multiple types of connectivity are allowed is still lacking. Here, we introduce a general framework to define and extract the core–periphery structure of multi-layer networks by explicitly taking into account the connectivity patterns at each layer. We first validate our algorithm on synthetic networks of different size and density, and with tunable overlap between the cores at different layers. We then use our method to merge information from structural and functional brain networks, obtaining in this way an integrated description of the core of the human connectome. Results confirm the role of the main known cortical and subcortical hubs, but also suggest the presence of new areas in the sensori-motor cortex that are crucial for intrinsic brain functioning. Taken together these findings provide fresh evidence on a fundamental question in modern neuroscience and offer new opportunities to explore the mesoscale properties of multimodal brain networks.

scholarly journals A Discussion of the Role of Frontoparietal Activity in Cognition

2007 ◽  
Vol 7 ◽  
pp. 1708-1714 ◽  
Author(s):  
Nicholas Hon
Keyword(s):  
Brain Imaging ◽  
Relevant Information ◽  
Functional Brain Imaging ◽  
Experimental Conditions ◽  
General Role ◽  
Cognitive Domains ◽  
Functional Brain

A consistently observed pattern in the functional brain imaging literature is that of joint frontal and parietal activation.  Because this pattern of activation has been observed under many different experimental conditions and when different cognitive domains have been tested, it is likely that frontoparietal activity plays a very general role in cognition.  This article considers one such possible role – the representation of behaviourally relevant information.

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