Nutrition and Bone Health in Older Adults

Author(s):  
Connie Bales ◽  
Kenlyn Young ◽  
John Anderson
Keyword(s):  
2015 ◽  
Vol 36 (9) ◽  
pp. 1117-1144 ◽  
Author(s):  
Eun-Shim Nahm ◽  
Barbara Resnick ◽  
Clayton Brown ◽  
Shijun Zhu ◽  
Jay Magaziner ◽  
...  

An estimated 10 million Americans age 50 and older have osteoporosis, and many experience associated fractures. Although several interventions have been shown to be effective in preventing osteoporosis, their impact on bone health among older adults was limited. The aim of this study was, therefore, to examine the effects of a theory-based online bone health program (Bone Power program) for a large number of older adults. The 8-week program included learning modules, discussion boards, and other resources. Participants ( N = 866; M age = 62.5 years) were recruited online and randomized into a Bone Power or control group. At the end of the intervention, the Bone Power group showed significantly greater improvement over the control group in osteoporosis knowledge, self-efficacy/outcome expectations for calcium intake and exercise, and calcium intake and exercise behaviors. This study’s findings suggest that online health programs can be effective in improving older adults’ knowledge, beliefs, and health behaviors.


2020 ◽  
Author(s):  
Mary E. Walsh ◽  
Tom Fahey ◽  
Frank Moriarty

ABSTRACTPurposeGaps in pharmacological treatment for osteoporosis can reduce effectiveness. This study aimed to estimate persistence rates for oral bisphosphonates and denosumab in older primary care patients and identify factors associated with discontinuation.MethodsOlder patients newly prescribed oral bisphosphonates or denosumab between 2012 and 2017 were identified from 44 general practices (GP) in Ireland. Persistence without a coverage gap of >90 days was calculated for both medications from therapy initiation. Factors associated with time to discontinuation were explored using Cox regression analysis. Exposures included age-group, osteoporosis diagnosis, fracture history, calcium/vitamin D prescription, number of other medications, health cover, dosing frequency (bisphosphonates) and previous bone-health medication (denosumab).ResultsOf 41,901 patients, n=1,569 newly initiated on oral bisphosphonates and n=1,615 on denosumab. Two-year persistence was 49.4% for oral bisphosphonates and 53.8% for denosumab and <10% were switched to other medication. Having state-funded health cover was associated with a lower hazard of discontinuation for both oral bisphosphonates (HR=0.49, 95%CI=0.36-0.66, p<0.01) and denosumab (HR=0.71, 95%CI=0.57-0.89, p<0.01). Older age-group, number of medications and calcium/vitamin D prescription were also associated with better bisphosphonate persistence while having osteoporosis diagnosed was associated with better denosumab persistence.ConclusionPersistence for osteoporosis medications is sub-optimal. Of concern, few patients are switched to other bone-health treatments when denosumab is stopped which could increase fracture risk. Free access to GP services and medications may have resulted in better medication persistence in this cohort. Future research should explore prescribing choices in primary-care osteoporosis management and evaluate cost-effectiveness of interventions for improving persistence.SUMMARYGaps in pharmacological treatment for osteoporosis can reduce its effectiveness. This study found approximately half of older adults in primary care newly initiated on bisphosphonates or denosumab were still taking these after 2 years. Abrupt discontinuation of denosumab without switching to an alternative is concerning due to increased fracture risk.


2011 ◽  
Vol 43 (Suppl 1) ◽  
pp. 251
Author(s):  
Elvio Rubio Gouveia ◽  
Cameron R. Blimkie ◽  
Duarte L. Freitas ◽  
José A. Maia ◽  
Gaston P. Beunen
Keyword(s):  

2018 ◽  
Vol 75 ◽  
pp. 125-131 ◽  
Author(s):  
David Scott ◽  
Catherine Shore-Lorenti ◽  
Lachlan McMillan ◽  
Jakub Mesinovic ◽  
Ross A. Clark ◽  
...  

2016 ◽  
Vol 61 (2) ◽  
pp. 99-114 ◽  
Author(s):  
E. A. Burke ◽  
P. McCallion ◽  
R. Carroll ◽  
J. B. Walsh ◽  
M. McCarron

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 15-15
Author(s):  
Liam Fouhy ◽  
Kelsey Mangano ◽  
Xiyuan Zhang ◽  
Brittany Adelman ◽  
Katherine Tucker ◽  
...  

Abstract Objectives Dietary calcium and magnesium have been shown to be beneficial for bone health primarily in non-Hispanic white populations.  There are no studies of calcium and magnesium intake among Hispanics of Caribbean origin. A calcium to magnesium ratio (Ca: Mg) may be important due to their competitive nature during absorption. This study examined associations between dietary calcium and magnesium and osteoporosis, accounting for calcium to magnesium ratio among Puerto Rican adults Methods Data from the Boston Puerto Rican Osteoporosis Study were used. Puerto Ricans aged 47–79 y with complete data on bone and diet were included (n = 955). Bone measures were assessed using dual-energy X-ray absorptiometry. A food frequency questionnaire adapted for this population was used. Dietary calcium and magnesium were energy adjusted using the residual method. Tertiles of Ca : Mg were calculate. Multivariable logistic regressions modeled associations between calcium, magnesium and tertiles of Ca : Mg. Model 1 included Ca : Mg tertiles and dietary magnesium; Model 2 Ca : Mg tertiles and dietary calcium; Model 3 Ca : Mg tertiles and dietary calcium and magnesium. All models were adjusted for age, estrogenic status (male, non-menopausal or taking estrogen, postmenopausal not taking estrogen), height, BMI, calcium (0, 0–300 mg, ≥300 mg) and magnesium (0, 0–100 mg) supplement use, serum vitamin D, alcohol use, smoking status, and bone medication use. Results Mean age was 59.9 y ± 7.6 and 71.3% were female. In model 1, the highest tertile of Ca : Mg was associated with higher likelihood (OR: 1.3; 95%CI: 0.77, 2.4) and the middle tertile with lower likelihood (OR: 0.51; 95%CI: 0.26,0.99) of osteoporosis compared with the lowest Ca: Mg tertile. Dietary magnesium was also associated with lower odds of osteoporosis (OR: 0.99; 95%CI: 0.98, 0.99). In model 2, dietary calcium (OR: 0.99, 95%CI: 0.99, 1.0) was associated with lower of odds osteoporosis, but Ca: Mg was not. In model 3, dietary calcium and magnesium and tertiles of Ca : Mg were not associated with osteoporosis. Conclusions Dietary calcium and magnesium are important nutrients for bone health in Puerto Rican older adults. The Ca : Mg ratio appears optimal within a range of 2.6–3.1 suggesting that a balance of these two nutrients is most important. Funding Sources National Institutes of Health P01 AG023394, P50 HL105185,  R01 AG027087 K01 AR067894


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