Estimation of Blood Alcohol Content with Bioimpedance Spectroscopy

2015 ◽  
pp. 35-44
2019 ◽  
Vol 64 (3) ◽  
pp. 365-371
Author(s):  
Michael Czaplik ◽  
Mark Ulbrich ◽  
Nadine Hochhausen ◽  
Rolf Rossaint ◽  
Steffen Leonhardt

Abstract The gold standard for estimating blood alcohol content (BAC) after alcohol consumption is a blood sample analysis. An innovative technology to estimate BAC is based on impedance cardiography and bioimpedance spectroscopy (BIS). This study investigated whether it is possible to estimate increasing blood alcohol levels during a drinking trial with bioimpedance measurement techniques. Twenty-one healthy volunteers were assigned to a test (ethanol) group (ETH) or a reference group (H2O). After baseline measurements, the ETH group ingested 120 ml of vodka, followed by a resorption phase of 50 min. Then, bioimpedance and breath alcohol measurements were performed. Thereafter, 60 ml of vodka was ingested and another resorption phase of 50 min was followed by bioimpedance and breath alcohol measurements. This procedure was repeated until alcohol levels exceeded 0.4 mg/l. The H2O group performed in the same way with water. For all measurements, extracellular resistance (Re) and the base impedance (Z0) were computed. Regarding BIS, several parameters differed significantly between the ETH and the H2O group. Re increased in ETH (p=0.005), but not in the H2O group when comparing the first and last measurements. Z0 also increased significantly in the ETH group (p=0.001). To conclude, with BIS measurements, it is possible to measure increasing blood alcohol levels.


2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Jean-François Hak ◽  
Farouk Tradi ◽  
Mickael Bobot ◽  
Pauline Brige ◽  
Paul Habert ◽  
...  

Objective. To evaluate the vascular occlusion and midterm tissue toxicity properties of a combination of ethylene-vinyl alcohol (EVOH) (Squid 18®) (75%) and alcohol (25%)—Alco-Squid 18—in a swine model. Materials and Methods. Alco-Squid 18 (75% Squid 18® mixed with 25% alcohol) (AS18) was compared to embolization with 96% alcohol alone and to embolization with Squid 18® (S18®) alone. An arteriovenous malformation (AVM) model was created in group 1 (n = 2). Each AVM model was then embolized with AS18 or S18® alone with evaluation of a ratio between the volume of embolic agent divided by the volume of the AVM (evaluated by CT). For group 2 (n = 5), each agent was tested on three different kidneys (upper pole kidney artery). Pre- and postinterventional CTs, angiographies, blood alcohol content dosages, and histological studies (3 months postintervention) were performed. Results. AS18 has better distal distribution than S18® alone, both in the kidneys (mean capsule-S18® distance: 3.9 mm (±0.23) and mean capsule-AS18 distance: 2.3 mm (±0.11) ( p = 0.029 ) and in the AVM model. Histological exploration found a higher rate of tubular necrosis with AS18 compared with S18® alone and alcohol alone (3.78 ± 0.44 compared to 2.33 ± 1.22 p   =  0 . 012 and 1.22 ± 0.67 p   < 0   . 0001 ). The blood alcohol content was negligible in all cases. Conclusion. AS18 can suggest a better distal sclerotic and embolic character as compared with S18® alone without systemic toxicity.


Author(s):  
Jerome Lapointe ◽  
Hélène-Sarah Bécotte-Boutin ◽  
Stéphane Gagnon ◽  
Simon Levasseur ◽  
Philippe Labranche ◽  
...  

One third of fatal car accidents and so much tragedies are due to alcohol abuse. These sad numbers could be mitigated if everyone had access to a breathalyzer anytime and anywhere. Having a breathalyzer built into a phone or a wearable could be the way to get around the reluctance to carry a separate device. Towards this goal, we propose an inexpensive breathalyzer that could be integrated in the screen of mobile devices. Our technology is based on the evaporation rate of the fog produced by the breath on the phone screen, which increases as a function of the breath alcohol content. The device simply uses a photodiode placed on the side of the screen to measure the signature of the scattered light intensity from the phone display that is guided through the stress layer of the Gorilla glass screen. A part of the display light is coupled to the stress layer via the evanescent field induced at the edge of the breath microdroplets. We demonstrate that the intensity signature measured at the detector can be linked to the blood alcohol content. We fabricated a prototype in a smartphone case powered by the phone&rsquo;s battery, controlled by an application software installed in the smartphone and tested it in real-world environments. Limitations and future work toward a fully operational device are discussed.


2020 ◽  
Vol 29 (7) ◽  
pp. 841-847
Author(s):  
Benjamin Cooper ◽  
Markus Gehrsitz ◽  
Stuart G. McIntyre

2013 ◽  
Vol 38 (3) ◽  
pp. 826-833 ◽  
Author(s):  
Marie Eliasen ◽  
Morten H. Rod ◽  
Trine Flensborg-Madsen ◽  
Jørgen H. Petersen ◽  
Morten Grønbaek ◽  
...  

Addiction ◽  
2002 ◽  
Vol 97 (7) ◽  
pp. 909-914 ◽  
Author(s):  
David T. Levy ◽  
Ted R. Miller ◽  
Sue Mallonee ◽  
Rebecca S. Spicer ◽  
Eduardo O. Romano ◽  
...  

2015 ◽  
Vol 105 (4) ◽  
pp. 1581-1617 ◽  
Author(s):  
Benjamin Hansen

I test the effect of harsher punishments and sanctions on driving under the influence (DUI). In this setting, punishments are determined by strict rules on blood alcohol content (BAC) and previous offenses. Regression discontinuity derived estimates suggest that having a BAC above the DUI threshold reduces recidivism by up to 2 percentage points (17 percent). Likewise having a BAC over the aggravated DUI threshold reduces recidivism by an additional percentage point (9 percent). The results suggest that the additional sanctions experienced by drunk drivers at BAC thresholds are effective in reducing repeat drunk driving. (JEL I12, K42, R41)


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