scholarly journals Dietary Phosphorus Restriction Reverses the Impaired Bone Mineralization in Vitamin D Receptor Knockout Mice

Endocrinology ◽  
2001 ◽  
Vol 142 (1) ◽  
pp. 494-497 ◽  
Author(s):  
Ritsuko Masuyama ◽  
Yumi Nakaya ◽  
Shinya Tanaka ◽  
Hiroshi Tsurukami ◽  
Toshitaka Nakamura ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Receptor ◽  
Knockout Mice ◽  
Bone Mineralization ◽  
Dietary Phosphorus

scholarly journals Vitamin D receptor is required to control gastrointestinal immunity in IL-10 knockout mice

Immunology ◽  
2006 ◽  
Vol 117 (3) ◽  
pp. 310-318 ◽  
Author(s):  
Monica Froicu ◽  
Yan Zhu ◽  
Margherita T. Cantorna
Keyword(s):  
Vitamin D ◽  
Vitamin D Receptor ◽  
Knockout Mice

Frontline Science: Concanavalin A‐induced acute hepatitis is attenuated in vitamin D receptor knockout mice with decreased immune cell function

2019 ◽  
Vol 106 (4) ◽  
pp. 791-801 ◽  
Author(s):  
Naoki Umeda ◽  
Kaori Endo‐Umeda ◽  
Hiroyuki Nakashima ◽  
Shigeaki Kato ◽  
Shuhji Seki ◽  
...  
Keyword(s):  
Vitamin D ◽  
Acute Hepatitis ◽  
Vitamin D Receptor ◽  
Concanavalin A ◽  
Knockout Mice ◽  
Cell Function ◽  
Immune Cell ◽  
Immune Cell Function

Tissue specificity and mechanism of vitamin D receptor up-regulation during dietary phosphorus restriction in the rat

2009 ◽  
Vol 10 (2) ◽  
pp. 271-280 ◽  
Author(s):  
Sutin Sriussadaporn ◽  
Man-Sau Wong ◽  
Wesley J. Pike ◽  
Murray J. Favus
Keyword(s):  
Vitamin D ◽  
Vitamin D Receptor ◽  
Tissue Specificity ◽  
Dietary Phosphorus

Swimming behaviour and post-swimming activity in Vitamin D receptor knockout mice

2006 ◽  
Vol 69 (1) ◽  
pp. 74-78 ◽  
Author(s):  
Thomas H.J. Burne ◽  
Amy N.B. Johnston ◽  
John J. McGrath ◽  
Alan Mackay-Sim
Keyword(s):  
Vitamin D ◽  
Vitamin D Receptor ◽  
Knockout Mice ◽  
Swimming Activity ◽  
Swimming Behaviour

scholarly journals Is the Vitamin D Receptor Found in Muscle?

Endocrinology ◽  
2010 ◽  
Vol 152 (2) ◽  
pp. 354-363 ◽  
Author(s):  
Yongji Wang ◽  
Hector F. DeLuca
Keyword(s):  
Vitamin D ◽  
Vitamin D Receptor ◽  
Bone Mineralization ◽  
Active Form ◽  
Dihydroxyvitamin D3 ◽  
Neuromuscular Activity ◽  
Immunohistochemical Assay ◽  
Underlying Mechanisms ◽  
Positive Results ◽  
Phosphorus Levels

Abstract The active form of vitamin D, 1α,25-dihydroxyvitamin D3, is critical for the regulation of serum calcium and phosphorus levels that in turn support bone mineralization and neuromuscular activity. It is well known that vitamin D deficiency causes rachitic/osteomalacic myopathy and cardiac disorder and the provision of vitamin D can reverse the symptoms. However, the underlying mechanisms remain unclear. The question of whether the vitamin D receptor is found in muscle has been debated but not settled. We recently studied all available antibodies against the vitamin D receptor and found that most antibodies used detect proteins other than the vitamin D receptor, and therefore, the utility of these antibodies may generate the false-positive results. Using antibodies that do not detect proteins in tissues from vitamin D receptor null mice, we have developed a specific and sensitive immunohistochemical assay. The results from this investigation show that the vitamin D receptor is undetectable in skeletal, cardiac, and smooth muscle, suggesting that the function of vitamin D on muscle is either of an indirect nature or does not involve the known receptor.

scholarly journals In Vitro and In Vivo Analysis of the Immune System of Vitamin D Receptor Knockout Mice

2001 ◽  
Vol 16 (11) ◽  
pp. 2057-2065 ◽  
Author(s):  
Chantal Mathieu ◽  
Evelyne Van Etten ◽  
Conny Gysemans ◽  
Brigitte Decallonne ◽  
Shigeaki Kato ◽  
...  
Keyword(s):  
Vitamin D ◽  
Immune System ◽  
Vitamin D Receptor ◽  
Knockout Mice ◽  
In Vivo Analysis

Metastatic growth of lung cancer cells is extremely reduced in Vitamin D receptor knockout mice

2004 ◽  
Vol 89-90 ◽  
pp. 545-547 ◽  
Author(s):  
Kimie Nakagawa ◽  
Akihiko Kawaura ◽  
Shigeaki Kato ◽  
Eiji Takeda ◽  
Toshio Okano
Keyword(s):  
Lung Cancer ◽  
Vitamin D ◽  
Cancer Cells ◽  
Vitamin D Receptor ◽  
Knockout Mice ◽  
Lung Cancer Cells ◽  
Metastatic Growth
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