Cluster headache and right-to-left shunt on contrast transcranial Doppler: A case-control study

Basilar artery dolichoectasia (BAD) is a disorder characterized by dilatation, elongation and tortuosity of the basilar artery. Transcranial Doppler ultrasound (TCD) is a useful tool that can detect blood flow in intracranial vessels including basilar artery (BA). Few studies have been conducted on blood flow changes in BAD. This study was conducted to evaluate the Doppler parameters in dolichoectatic BA and to assess if there is any difference in TCD findings between stroke and non-stroke BAD patients. A case-control study was conducted on 35 patients diagnosed with BAD (26 male, 9 female) and 35 age- and gender-matched control group (without BAD) at the Middle Euphrates Neuroscience Center, Al-Sader Medical City, Al-Najaf, Iraq. Dolichoectasia was diagnosed on non-enhanced brain CT scan using established imaging criteria according to Dan Deng et al criteria. Doppler flow for control and stroke cases was recorded. The parameters measured on TCD were peak systolic velocity (PSV), end diastolic velocity (EDV) mean blood velocity (MBV), pulsatility index (PI) and resistive index (RI). After logistic regression for adjustment for the significant confounders, there was statistically significant difference in Doppler parameters between both groups including decrease in each of PSV, EDV and MBV while both PI and RI weren’t statistically significant. Among BAD patients, there was statistically significant difference in all TCD parameters between stroke and non-stroke patients (PSV EDV, MBV, PI and RI). BAD was associated with a decrease in flow velocities as measured by TCD. Furthermore, among BAD patients, those with stroke had lower values for all Doppler parameters than non-stroke patients.

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A Case-Control Study on Cortical Thickness in Episodic Cluster Headache

Headache The Journal of Head and Face Pain ◽

10.1111/j.1526-4610.2012.02217.x ◽

2012 ◽

Vol 52 (9) ◽

pp. 1362-1368 ◽

Cited By ~ 17

Author(s):

Christian L. Seifert ◽

Stefano Magon ◽

Kathrin Staehle ◽

Claus Zimmer ◽

Annette Foerschler ◽

...

Keyword(s):

Cluster Headache ◽

Cortical Thickness ◽

Case Control Study ◽

Case Control ◽

Episodic Cluster Headache ◽

Control Study

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Prevalence and extent of right-to-left shunt on contrast-enhanced transcranial Doppler in Chinese patients with migraine in a multicentre case-control study

Cephalalgia ◽

10.1177/0333102417708203 ◽

2017 ◽

Vol 38 (4) ◽

pp. 690-696 ◽

Cited By ~ 6

Author(s):

Si-Bo Wang ◽

Kang-Ding Liu ◽

Yi Yang ◽

Ya-Jie Li ◽

Ming-Yi Hu ◽

...

Keyword(s):

Migraine With Aura ◽

Transcranial Doppler ◽

Migraine Without Aura ◽

Case Control Study ◽

Case Control ◽

Chinese Patients ◽

Healthy Group ◽

Contrast Enhanced ◽

Positive Rate ◽

Control Study

Background The association between RLS and migraine is still debated. The aim of this study is to investigate the prevalence and grade of RLS in Chinese patients with migraine and to evaluate the relationship between RLS and migraine. Methods A multi-center case-control study of contrast-enhanced transcranial Doppler was conducted in 931 consecutive patients with migraine (240 of 931 had migraine with aura and 691 of 931 were in the migraine without aura group) and 282 were healthy adults. Clinical trial no. NCT02425696. Results The prevalence of RLS was 63.8% and 39.9% in the migraine with aura group (MA+) and migraine without aura group (MA−), respectively, significantly higher than that of the healthy group (29.4%, p < 0.001; p < 0.001). The positive rate of large RLS in the MA+ group and MA− group was 32.1% and 16.5%, respectively, significantly higher than healthy group (6.4%, p < 0.001; p < 0.001). There was no difference among groups in terms of positive rate of permanent RLS ( p = 0.704). Conclusion This multi-centre case-control study suggested that there is an association between RLS and migraine with and without aura, especially when the shunt is large.

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Transcranial doppler findings in basilar artery dolichoectasia: a case control study

American Journal of BioMedicine ◽

10.18081/2333-5106/9.4/18 ◽

2021 ◽

Vol 9 (4) ◽

pp. 177-188

Keyword(s):

Blood Flow ◽

Basilar Artery ◽

Transcranial Doppler ◽

Case Control Study ◽

Peak Systolic Velocity ◽

Case Control ◽

Control Group ◽

Stroke Patients ◽

Significant Difference ◽

Control Study

Basilar artery dolichoectasia (BAD) is a disorder characterized by dilatation, elongation and tortuosity of the basilar artery. Transcranial Doppler ultrasound (TCD) is a useful tool that can detect blood flow in intracranial vessels including basilar artery (BA). Few studies have been conducted on blood flow changes in BAD. This study was conducted to evaluate the Doppler parameters in dolichoectatic BA and to assess if there is any difference in TCD findings between stroke and non-stroke BAD patients. A case-control study was conducted on 35 patients diagnosed with BAD (26 male, 9 female) and 35 age- and gender-matched control group (without BAD) at the Middle Euphrates Neuroscience Center, Al-Sader Medical City, Al-Najaf, Iraq. Dolichoectasia was diagnosed on non-enhanced brain CT scan using established imaging criteria according to Dan Deng et al criteria. Doppler flow for control and stroke cases was recorded. The parameters measured on TCD were peak systolic velocity (PSV), end diastolic velocity (EDV) mean blood velocity (MBV), pulsatility index (PI) and resistive index (RI). After logistic regression for adjustment for the significant confounders, there was statistically significant difference in Doppler parameters between both groups including decrease in each of PSV, EDV and MBV while both PI and RI weren’t statistically significant. Among BAD patients, there was statistically significant difference in all TCD parameters between stroke and non-stroke patients (PSV EDV, MBV, PI and RI). BAD was associated with a decrease in flow velocities as measured by TCD. Furthermore, among BAD patients, those with stroke had lower values for all Doppler parameters than non-stroke patients.

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