Hemangiomatous Anomaly of Bone in Crouzon's Syndrome: Case Report

Abstract A striking and diffuse hemangiomatous architecture was identified by microscopic examination of bone specimens obtained at cranial synostectomy and from the craniofacial area of a young boy with Kleeblättschadel deformity and Crouzon's syndrome. A retrospective review of the histopathological appearance of bone specimens from other patients with Crouzon's syndrome treated on our service and a review of the literature on craniosynostosis suggest that the hemangiomatous pattern seen in this patient is rare if not unique. The unusual pathological findings provide evidence that the underlying pathophysiology of this disorder may be heterogeneous.

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Neuropsychiatric Derangement by Polycythemia Vera: A Case Report of an Unexpected Disease Presentation and Review of the Literature

Acta Haematologica ◽

10.1159/000516441 ◽

2021 ◽

pp. 1-6

Author(s):

Heleen De Lil ◽

Michelle van Beek ◽

Alexandra Herbers ◽

Ellen van der Holst ◽

Karen Keijsers

Keyword(s):

Case Report ◽

Chronic Disease ◽

Cerebral Infarction ◽

Polycythemia Vera ◽

Neuropsychiatric Symptoms ◽

Unusual Presentation ◽

Review Of The Literature ◽

Remarkable Recovery ◽

Visual Complaints ◽

Underlying Pathophysiology

Cerebral infarction as well as other thromboses, headaches, and visual complaints are well-known symptoms of polycythemia vera. However, chorea and neuropsychiatric disturbances are less recognized consequences of this chronic disease. Whereas chorea is a rare but acknowledged symptom of polycythemia vera, neuropsychiatric symptoms have only sporadically been reported. We depict 2 patients with an unusual presentation of polycythemia vera. Our first patient presented with right-sided hemiballism and psychosis, and the second patient had a long diagnostic trajectory of unexplained chorea. In both cases diagnosis of JAK2 positive polycythemia vera was established, and in both cases remarkable recovery occurred after the initiation of phlebotomies. The underlying pathophysiology of these symptoms has not been clearly elucidated. Because of the unfamiliarity of the link between especially neuropsychiatric symptoms and polycythemia, current reported numbers are probably an underestimation. Benefit of treatment appears to be large. We seek to create more awareness among physicians about this phenomenon.

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Three-Millimeter Apocrine Adenoma in a Man: A Case Report and Review of the Literature

Archives of Pathology & Laboratory Medicine ◽

10.5858/2003-127-1498-taaiam ◽

2003 ◽

Vol 127 (11) ◽

pp. 1498-1500

Author(s):

Melissa A. Pasquale-Styles ◽

Clara Milikowski

Keyword(s):

Case Report ◽

Microscopic Examination ◽

Rare Case ◽

Excisional Biopsy ◽

Left Breast ◽

Review Of The Literature ◽

Granular Eosinophilic Cytoplasm ◽

Eosinophilic Cytoplasm ◽

Hypoechoic Nodule

Abstract We describe a rare case of apocrine adenoma of the breast in a 45-year-old man. The patient presented with a tender lump in his left breast that had been present for 6 months. A mammogram identified a 3-mm nodular density in the breast, which was described as a hypoechoic nodule on ultrasound. Microscopic examination of tissue from an excisional biopsy revealed a 3-mm group of benign glands with abundant granular, eosinophilic cytoplasm and apical luminal blebbing, consistent with an apocrine adenoma. After reviewing other reported apocrine adenomas in the literature, we determined that our case was the smallest detected apocrine adenoma to be reported to date.

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Eccrine Porocarcinoma: A Case Report and Review of the Literature

Canadian Journal of Plastic Surgery ◽

10.1177/229255030301100304 ◽

2003 ◽

Vol 11 (3) ◽

pp. 153-156 ◽

Cited By ~ 9

Author(s):

Mark Sheldon Lloyd ◽

Naguib El-Muttardi ◽

A Robson

Keyword(s):

Case Report ◽

Skin Cancer ◽

Natural History ◽

Current Literature ◽

Typical Case ◽

Pathological Findings ◽

Review Of The Literature ◽

Rare Form ◽

Skin Malignancy ◽

Eccrine Porocarcinoma

Eccrine porocarcinoma is a rare form of skin cancer that is often con-fused with other types of skin malignancy The present paper high-lights a typical case to remind plastic surgeons of the natural history, pathological findings and current literature on the management of this cancer.

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Anaplastic Ganglioglioma in an Infant: Case Report and Review of the Literature

Neurosurgery ◽

10.1227/00006123-198612000-00019 ◽

1986 ◽

Vol 19 (6) ◽

pp. 1016-1020 ◽

Cited By ~ 44

Author(s):

Walter A. Hall ◽

Eduardo J. Yunis ◽

Leland A. Albright

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Case Report ◽

Microscopic Examination ◽

Tumor Recurrence ◽

Ct Scans ◽

Review Of The Literature ◽

Pertinent Literature ◽

Computed Tomographic ◽

Infant Case

Abstract A 6-month-old girl had a gradually increasing head circumference. A preoperative computed tomographic (CT) scan of the head revealed an enhancing calcified partially cystic right frontal mass that was removed through a right frontotemporal craniotomy. On microscopic examination, the tumor was composed of sheets of neurons in a glial background alternating with highly cellular anaplastic areas. The diagnosis of anaplastic ganglioglioma was made. The child has done well for the 20 months since the operation without any evidence of tumor recurrence on subsequent CT scans. Because of the immaturity of the child's developing central nervous system, we have elected not to initiate radiotherapy at this time. The pertinent literature regarding gangliogliomas is reviewed.

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Cystic Falcine Chondroma: Case Report and Review of the Literature

Neurosurgery ◽

10.1227/00006123-199112000-00019 ◽

1991 ◽

Vol 29 (6) ◽

pp. 909-912 ◽

Cited By ~ 10

Author(s):

Karim Hadadian ◽

Hossein Abtahii ◽

Zahra T. Asil ◽

Mohammad Rakhshan ◽

Parvin Vessal

Keyword(s):

Case Report ◽

Microscopic Examination ◽

Rare Case ◽

Cystic Degeneration ◽

Review Of The Literature ◽

Resected Tumor ◽

History Of

Abstract A rare case of falcine chondroma in a 25-year-old woman with an 8-year history of headache and a recent generalized seizure is presented. Microscopic examination of the resected tumor revealed that it was a falcine chondroma with chondrocytes and central cystic degeneration.

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Wernicke's Disease and Schizophrenia: A Case Report and Review of the Literature

The International Journal of Psychiatry in Medicine ◽

10.2190/gd76-1up3-tr18-ypyh ◽

1996 ◽

Vol 26 (3) ◽

pp. 319-328 ◽

Cited By ~ 8

Author(s):

Manuel F. Casanova

Keyword(s):

Case Report ◽

Intraventricular Hemorrhage ◽

Dietary Habits ◽

Postmortem Examination ◽

Pathological Findings ◽

Review Of The Literature ◽

Fatal Complication ◽

High Prevalence ◽

Schizophrenic Patients ◽

Alternate Possibility

Objectives: A review of the neuropathology literature in schizophrenia suggests that some patients with this disease exhibit periventricular gliosis at postmortem examination. Several researchers have speculated that this finding is the remnant of either a prior viral infection or a gestational intraventricular hemorrhage. The present article uses a case report to hypothesize and discuss an alternate possibility to the putative gliosis, namely Wernicke's disease. Method: Based on the pathological findings of our patient and a review of the literature, the author summarizes several reasons why Wernicke's disease may occur, and still be unnoticed, in some schizophrenic patients. Results: Inefficient self-care and homelessness predisposes some patients with schizophrenia to poor dietary habits and malnutrition. Similarly, the high prevalence of concurrent alcoholism in patients with schizophrenia may propitiate thiamine deficiency. The resulting brain insult may be compounded by disturbances of carbohydrate metabolism which may be peculiar to the schizophrenic process itself, or acquired, as in coincidental diabetes. Conclusions: Since symptoms accrued to Wernicke's may often be subtle and obscured by other schizophreniform manifestations, clinicians should lower their threshold for suspecting this potentially fatal complication. The diagnostic possibility of Wernicke's should be especially entertained in schizophrenic patients who are alcoholics and/or diabetics.

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Villous Adenocarcinoma of the Duodenum Invading the Ampulla of Vater: Case Report and Review of Literature

HPB Surgery ◽

10.1155/1996/32596 ◽

1996 ◽

Vol 10 (2) ◽

pp. 105-109 ◽

Cited By ~ 1

Author(s):

Gaetano Catania ◽

Francesco Cardi ◽

Marcello Migliore ◽

Gaetano Romeo

Keyword(s):

Case Report ◽

Surgical Treatment ◽

Microscopic Examination ◽

Villous Adenoma ◽

Ampulla Of Vater ◽

Review Of Literature ◽

Review Of The Literature ◽

Endoscopic Biopsies ◽

Well Differentiated

We report a case of villous adenocarcinoma of duodenum arising from the ampulla of Vater with a review of the literature. Although preoperative endoscopic biopsies were performed, no malignancy was identified. Because of the pathological uncertainty we decided to perform a pylorus-preserving pancreatoduodenectomy. Microscopic examination demonstrated glandular dysplasia with aspects of villous adenoma and well differentiated adenocarcinoma. We conclude that both in malignant cases and in cases with uncertain diagnosis a pylorus-preserving pancreatoduodenectomy is the best surgical treatment because it results in better 5 year survival.

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