scholarly journals What lies beyond 100 years of insulin

2021 ◽  
Vol 14 (11) ◽  
Author(s):  
Kirsty M. Hooper
Keyword(s):  
Public Health ◽  
Metabolic Syndrome ◽  
Clinical Research ◽  
Health Impact ◽  
Public Health Impact ◽  
Disease Models ◽  
High Quality

ABSTRACT It has been 100 years since the discovery of insulin. This revolutionary treatment saves the lives of millions of people living with diabetes, but much remains to be understood of its mechanisms and roles in homeostasis and disease. To celebrate this centenary, we explore areas of ongoing insulin research in diabetes, metabolic syndrome and beyond. Disease Models & Mechanisms aims to publish high-quality basic and pre-clinical research that advances our understanding of these conditions to facilitate clinical and public health impact.

scholarly journals Integrating implementation science in clinical research to maximize public health impact: a call for the reporting and alignment of implementation strategy use with implementation outcomes in clinical research

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Brittany N. Rudd ◽  
Molly Davis ◽  
Rinad S. Beidas
Keyword(s):  
Public Health ◽  
Clinical Research ◽  
Implementation Research ◽  
Implementation Strategy ◽  
Health Impact ◽  
Strategy Use ◽  
Reporting Guidelines ◽  
Public Health Impact ◽  
Main Body ◽  
Implementation Outcomes

Abstract Background Although comprehensive reporting guidelines for implementation strategy use within implementation research exist, they are rarely used by clinical (i.e., efficacy and effectiveness) researchers. In this debate, we argue that the lack of comprehensive reporting of implementation strategy use and alignment of those strategies with implementation outcomes within clinical research is a missed opportunity to efficiently narrow research-to-practice gaps. Main body We review ways that comprehensively specifying implementation strategy use can advance science, including enhancing replicability of clinical trials and reducing the time from clinical research to public health impact. We then propose that revisions to frequently used reporting guidelines in clinical research (e.g., CONSORT, TIDieR) are needed, review current methods for reporting implementation strategy use (e.g., utilizing StaRI), provide pragmatic suggestions on how to both prospectively and retrospectively specify implementation strategy use and align these strategies with implementation outcomes within clinical research, and offer a case study of using these methods. Conclusions The approaches recommended in this article will not only contribute to shared knowledge and language among clinical and implementation researchers but also facilitate the replication of efficacy and effectiveness research. Ultimately, we hope to accelerate translation from clinical to implementation research in order to expedite improvements in public health.

Public Health Impact of Substance Use on Adolescent: A Snapshot of Yenagoa in Bayelsa State. Nigeria

2019 ◽  
Author(s):  
Morufu Raimi ◽  
Abdulraheem Aishat Funmilayo ◽  
Iteimowei Major ◽  
Okoyen Ebikapaye ◽  
Olaolu Oyinlola Bilewu
Keyword(s):  
Public Health ◽  
Substance Use ◽  
Health Impact ◽  
Public Health Impact

Analyzing the FDA Priority Review Voucher Program's Stimulation of Research and Public Health Impact

2016 ◽  
Vol 3 (2) ◽  
pp. 131-141
Author(s):  
Chris Bialas ◽  
Elizabeth Higbee-Dempsey ◽  
Cindy Y. Chen ◽  
Caitlin Ward ◽  
Oscar A Marcos-Contreras ◽  
...  
Keyword(s):  
Public Health ◽  
Health Impact ◽  
Public Health Impact ◽  
Priority Review ◽  
Stimulation Of
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