scholarly journals Non-membranous granular organelle consisting of PCM-1: subcellular distribution and cell-cycle-dependent assembly/disassembly

2003 ◽  
Vol 116 (5) ◽  
pp. 919-928 ◽  
Author(s):  
A. Kubo
Keyword(s):  
Cell Cycle ◽  
Subcellular Distribution ◽  
Cycle Dependent

Cell-cycle dependent subcellular distribution and mitogenic effects of PTOV1, a novel protein overexpressed in prostate cancer

2003 ◽  
Vol 2 (1) ◽  
pp. 161
Author(s):  
A. Santamaria ◽  
P. Fernandez ◽  
X. Farre ◽  
P. Benedit ◽  
Joan Morote ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Cycle ◽  
Subcellular Distribution ◽  
Cycle Dependent ◽  
Novel Protein

Cell cycle-dependent subcellular distribution of ClC-3 in HeLa cells

2012 ◽  
Vol 137 (6) ◽  
pp. 763-776 ◽  
Author(s):  
Jianwen Mao ◽  
Xiaobo Li ◽  
Weiqiang Chen ◽  
Bin Xu ◽  
Haifeng Zhang ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Hela Cells ◽  
Subcellular Distribution ◽  
Cycle Dependent

scholarly journals Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells

1992 ◽  
Vol 117 (1) ◽  
pp. 213-224 ◽  
Author(s):  
P Gallant ◽  
EA Nigg
Keyword(s):  
Cell Cycle ◽  
Hela Cells ◽  
Subcellular Distribution ◽  
Nuclear Translocation ◽  
Mitotic Spindles ◽  
Cycle Arrest ◽  
Regulatory Machinery ◽  
Essential Components ◽  
Cycle Dependent ◽  
Monospecific Antibodies

Cyclin proteins form complexes with members of the p34cdc2 kinase family and they are essential components of the cell cycle regulatory machinery. They are thought to determine the timing of activation, the subcellular distribution, and/or the substrate specificity of cdc2-related kinases, but their precise mode of action remains to be elucidated. Here we report the cloning and sequencing of avian cyclin B2. Based on the use of monospecific antibodies raised against bacterially expressed protein, we also describe the subcellular distribution of cyclin B2 in chick embryo fibroblasts and in DU249 hepatoma cells. By indirect immunofluorescence microscopy we show that cyclin B2 is cytoplasmic during interphase of the cell cycle, but undergoes an abrupt translocation to the cell nucleus at the onset of mitotic prophase. Finally, we have examined the phenotypic consequences of expressing wild-type and mutated versions of avian cyclin B2 in HeLa cells. We found that expression of cyclin B2 carrying a mutation at arginine 32 (to serine) caused HeLa cells to arrest in a pseudomitotic state. Many of the arrested cells displayed multiple mitotic spindles, suggesting that the centrosome cycle had continued in spite of the cell cycle arrest.

Molecular Cloning, Chromosomal Localization, and Cell Cycle-Dependent Subcellular Distribution of the A-Kinase Anchoring Protein, AKAP95

1998 ◽  
Vol 238 (2) ◽  
pp. 305-316 ◽  
Author(s):  
Turid Eide ◽  
Vince Coghlan ◽  
Sigurd Ørstavik ◽  
Christian Holsve ◽  
Rigmor Solberg ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Molecular Cloning ◽  
Subcellular Distribution ◽  
Chromosomal Localization ◽  
Anchoring Protein ◽  
Cycle Dependent

scholarly journals Cell cycle dependent subcellular distribution of Cdc25B subtypes

Oncogene ◽  
1999 ◽  
Vol 18 (17) ◽  
pp. 2770-2776 ◽  
Author(s):  
Elizabeth S Woo ◽  
Robert L Rice ◽  
John S Lazo
Keyword(s):  
Cell Cycle ◽  
Subcellular Distribution ◽  
Cycle Dependent

Cell cycle dependent modulation of insulin and IGF I receptor binding to human Burkitt type ALL cells

1987 ◽  
Vol 116 (3_Suppl) ◽  
pp. S81
Author(s):  
U. VETTER ◽  
W. HARTMANN ◽  
H. HITZLER ◽  
W. HEIT ◽  
J. SCHLICKENRIEDER ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Receptor Binding ◽  
Igf I ◽  
Cycle Dependent
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