Deep Lymph Node Metastases in the Groin Significantly Affects Prognosis, Particularly in Sentinel Node-Positive Melanoma Patients

2014 ◽  
Vol 22 (1) ◽  
pp. 279-286 ◽  
Author(s):  
M. G. Niebling ◽  
K. P. Wevers ◽  
A. J. H. Suurmeijer ◽  
R. J. van Ginkel ◽  
Harald J. Hoekstra
Keyword(s):  
Lymph Node ◽  
Sentinel Node ◽  
Lymph Node Metastases ◽  
Node Positive ◽  
Node Metastases ◽  
Melanoma Patients

Pre-SN Ultrasound-FNAC for Lymph Node Metastases in Melanoma Patients: A Reply

2017 ◽  
Vol 24 (S3) ◽  
pp. 663-664
Author(s):  
Christy Chai ◽  
Margaret Szabunio ◽  
Christopher Cook ◽  
Jonathan Zager ◽  
Jane Messina ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastases ◽  
Node Metastases ◽  
Melanoma Patients

Sentinel node detection with radiocolloid lymphatic mapping in early invasive cervical cancer

2005 ◽  
Vol 15 (2) ◽  
pp. 273-277 ◽  
Author(s):  
Y. S. Lin ◽  
C. C. Tzeng ◽  
K. F. Huang ◽  
C. Y. Kang ◽  
C. C. Chia ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Lymph Node ◽  
Sentinel Node ◽  
Lymph Node Metastases ◽  
Lymphatic Mapping ◽  
Invasive Cervical Cancer ◽  
False Negative ◽  
Sentinel Node Detection ◽  
Sentinel Nodes ◽  
Node Metastases

We assessed the feasibility of sentinel lymph node detection using technicium-99 radiocolloid lymphatic mapping for predicting lymph node metastases in early invasive cervical cancer. Thirty patients with cervical cancer (stages IA2–IIA) underwent preoperative lymphoscintigraphy using technicium-99 intracervical injection and intraoperative lymphatic mapping with a handheld gamma probe. After dissection of the sentinel nodes, the standard procedure of pelvic lymph node dissection and radical hysterectomy was performed as usual. The sentinel node detection rate was 100% (30/30). There were seven (23.3%) cases of microscopic lymph node metastases on pathologic analysis. All of them had sentinel node involvement. Therefore, the sensitivity of sentinel node identification for prediction of lymph node metastases was 100%, and no false negative was found. Preoperative lymphoscintigraphy, coupled with intraoperative lymphatic mapping, located the sentinel nodes accurately in our study patients. This sentinel node detection method appears to be feasible for predicting lymph node metastases

Level of Fluorodeoxyglucose Uptake Predicts Risk for Recurrence in Melanoma Patients Presenting With Lymph Node Metastases

2006 ◽  
Vol 13 (7) ◽  
pp. 919-926 ◽  
Author(s):  
Esther Bastiaannet ◽  
Otto S. Hoekstra ◽  
Wim J. G. Oyen ◽  
Piet L. Jager ◽  
Theo Wobbes ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastases ◽  
Node Metastases ◽  
Melanoma Patients

Histopathological characteristics of lymph node metastases predict cancer-specific survival in node-positive prostate cancer

2008 ◽  
Vol 102 (11) ◽  
pp. 1589-1593 ◽  
Author(s):  
Joost L. Boormans ◽  
Mark F. Wildhagen ◽  
Chris H. Bangma ◽  
Paul C. Verhagen ◽  
Geert J. van Leenders
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Cancer Specific Survival ◽  
Node Positive ◽  
Node Metastases

Prospective Study of Fluorodeoxyglucose–Positron Emission Tomography Imaging of Lymph Node Basins in Melanoma Patients Undergoing Sentinel Node Biopsy

1999 ◽  
Vol 17 (5) ◽  
pp. 1508-1508 ◽  
Author(s):  
Jeffrey D. Wagner ◽  
Donald Schauwecker ◽  
Darrell Davidson ◽  
John J. Coleman III ◽  
Scott Saxman ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Node ◽  
Lymph Node Metastases ◽  
Fdg Pet ◽  
Regional Lymph Node ◽  
Emission Tomography ◽  
Node Biopsy ◽  
Positron Emission ◽  
Node Metastases

PURPOSE: To prospectively compare positron emission tomography (PET) imaging of regional lymph node basins to sentinel node biopsy (SNB) in patients with American Joint Committee on Cancer (AJCC) stage I, II, and III melanoma localized to the skin. METHODS: Patients with cutaneous melanoma with Breslow's depth greater than 1 mm (AJCC T2-4N0M0) or localized regional cutaneous recurrence (TxN2bM0) underwent whole-body imaging of glucose metabolism with fluorodeoxyglucose (FDG) PET followed by SNB. PET scans were interpreted in a blinded fashion and compared with histologic analyses of SNB specimens and clinical follow-up examination. Nodal tumor volumes were estimated. RESULTS: Eighty-nine lymph node basins were evaluated by FDG-PET and SNB in 70 assessable patients. Eighteen patients (25.7%) had lymph node metastases at the time of FDG-PET imaging: 17 proved by SNB (24.3%) and one by follow-up examination (1.4%). Median tumor volume in positive sentinel node basins was 4.3 mm3 (range, 0.07 to 523 mm3). Sensitivity of SNB for detection of occult regional lymph node metastases was 94.4%, specificity was 100%, positive predictive value (PPV) was 100%, and negative predictive value (NPV) was 98.6%. Sensitivity of FDG-PET was 16.7%, specificity was 95.8%, PPV was 50%, and NPV was 81.9%. At a median follow-up duration of 16.6 months, seven patients (10%) developed recurrent disease. PET predicted one recurrence (14.3%) in a node basin missed by SNB. CONCLUSION: FDG-PET is an insensitive indicator of occult regional lymph node metastases in patients with melanoma because of the minute tumor volumes in this population. FDG-PET does not have a primary role for staging regional nodes in patients with clinically localized melanoma.

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