scholarly journals Potentiation of host-mediated antitumor activity in mice by .BETA.-glucan obtained from Grifola frondosa (maitake)

1987 ◽  
Vol 35 (1) ◽  
pp. 262-270 ◽  
Author(s):  
KYOKO ADACHI ◽  
HIROAKI NANBA ◽  
HISATORA KURODA
Keyword(s):  
Antitumor Activity ◽  
Grifola Frondosa ◽  
Beta Glucan

scholarly journals Chemical Modification and Antitumor Activity of Polysaccharides from the Mycelium of Liquid-cultured Grifola frondosa.

1994 ◽  
Vol 41 (10) ◽  
pp. 733-740 ◽  
Author(s):  
Cun ZHUANG ◽  
Takashi MIZUNO ◽  
Hitoshi ITO ◽  
Keishiro SHIMURA
Keyword(s):  
Antitumor Activity ◽  
Chemical Modification ◽  
Grifola Frondosa

scholarly journals Antitumor activity of a polysaccharide fraction extracted from cultured fruiting bodies of Grifola frondosa.

1984 ◽  
Vol 7 (7) ◽  
pp. 492-500 ◽  
Author(s):  
IWAO SUZUKI ◽  
TERU ITANI ◽  
NAOHITO OHNO ◽  
SHOZO OIKAWA ◽  
KICHIRO SATO ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Grifola Frondosa ◽  
Fruiting Bodies ◽  
Polysaccharide Fraction

scholarly journals Antitumor and immunomodulating activites of a .BETA.-glucan obtained from liquid-cultured Grifola frondosa.

1989 ◽  
Vol 37 (2) ◽  
pp. 410-413 ◽  
Author(s):  
Iwao SUZUKI ◽  
Koichi HASHIMOTO ◽  
Shozo OIKAWA ◽  
Kichiro SATO ◽  
Masumi OSAWA ◽  
...  
Keyword(s):  
Grifola Frondosa ◽  
Beta Glucan

scholarly journals Structural Elucidation and Immune-Enhancing Effects of Novel Polysaccharide from Grifola frondosa

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Yu-Ri Seo ◽  
Dinesh K. Patel ◽  
Woo-Chul Shin ◽  
Wan-Sup Sim ◽  
Ok-Hwan Lee ◽  
...  
Keyword(s):  
Particle Size ◽  
Cell Activation ◽  
Cell Activity ◽  
Food Additive ◽  
Grifola Frondosa ◽  
Immunological Activity ◽  
Beta Glucan ◽  
Hypoglycemic Agent ◽  
Immune Booster ◽  
Cytokines Secretion

Beta-glucan (β-glucan) is a macromolecule structure where glucose unit has bonded through β-glycosidic bond at 1 and 3 positions. It is well known as a natural immunomodulator without exhibiting any side effects via enhancing immunity. Mushroom contains a large amount of β-glucan and it has anticancerous and antioxidant efficacy. Structure and physical properties of β-glucan are highly influenced by the types of mushroom. In particular, Grifola frondosa has β-1, 3 and β-1, 6 bonds in their structure. It has been noted that β-glucan content also depends upon the size of mushroom particles. The exact content of β-glucan and their immunological activity by a particle size of G. frondosa have yet to be fully elucidated. Herein, β-glucan contents were analyzed according to the particle size of leaf mushroom followed by cell activation and immunoactivity analysis. The highest β-glucan content was observed at a particle size of 20-30 μm (27.65 ± 0.30 w/w). All samples showed ~ 103% cell activation compared to the control and greater cell activity was observed at higher concentration. The significant increase in cytokines secretion was observed in the presence of 20-30 μm particle size of G. frondosa compared to the control. This study suggested that 20-30 μm size is the suitable size of G. frondosa that can be used as a health supplement and food additive to act as an immune booster, hypotensive agent, and hypoglycemic agent.

scholarly journals High- and low-Molecular Weight oat Beta-Glucan Reveals Antitumor Activity in Human Epithelial Lung Cancer

2017 ◽  
Vol 24 (3) ◽  
pp. 583-592 ◽  
Author(s):  
Anna Choromanska ◽  
Julita Kulbacka ◽  
Joanna Harasym ◽  
Remigiusz Oledzki ◽  
Anna Szewczyk ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Molecular Weight ◽  
Antitumor Activity ◽  
Low Molecular Weight ◽  
Beta Glucan

scholarly journals Antitumor Activity and Immunological Property of Polysaccharides from the Mycelium of Liquid-Cultured Grifola frondosa.

1994 ◽  
Vol 41 (10) ◽  
pp. 724-732 ◽  
Author(s):  
Cun ZHUANG ◽  
Takashi MIZUNO ◽  
Hitoshi ITO ◽  
Keishiro SHIMURA ◽  
Toshimitsu SUMIYA ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Grifola Frondosa ◽  
Immunological Property

scholarly journals Preparation of Antibody against Antitumor .BETA.-Glucan in Grifola frondosa and Its Application.

1999 ◽  
Vol 5 (4) ◽  
pp. 398-401 ◽  
Author(s):  
Masashi MIZUNO ◽  
Akio YAMAKAWA ◽  
Ken-ichiro MINATO ◽  
Sachiko KAWAKAMI ◽  
Shigenobu TATSUOKA ◽  
...  
Keyword(s):  
Grifola Frondosa ◽  
Beta Glucan
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