SATELLITE CELL AND GROWTH FACTOR INVOLVEMENT IN SKELETAL MUSCLE GROWTH.

1980 ◽  
Vol 21 (Supplement) ◽  
pp. S30
Author(s):  
Timothy P. White
Keyword(s):  
Skeletal Muscle ◽  
Growth Factor ◽  
Satellite Cell ◽  
Muscle Growth ◽  
Skeletal Muscle Growth

scholarly journals Prepubertal skeletal muscle growth requires Pax7-expressing satellite cell-derived myonuclear contribution

Development ◽  
2018 ◽  
Vol 145 (20) ◽  
pp. dev167197 ◽  
Author(s):  
John F. Bachman ◽  
Alanna Klose ◽  
Wenxuan Liu ◽  
Nicole D. Paris ◽  
Roméo S. Blanc ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Satellite Cell ◽  
Muscle Growth ◽  
Skeletal Muscle Growth

scholarly journals The imprinted gene Pw1/Peg3 regulates skeletal muscle growth, satellite cell metabolic state, and self-renewal

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Rosa Maria Correra ◽  
David Ollitrault ◽  
Mariana Valente ◽  
Alessia Mazzola ◽  
Bjorn T. Adalsteinsson ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Satellite Cell ◽  
Muscle Growth ◽  
Metabolic State ◽  
Self Renewal ◽  
Imprinted Gene ◽  
Skeletal Muscle Growth

Activation of insulin-like growth factor gene expression during work-induced skeletal muscle growth

1990 ◽  
Vol 259 (1) ◽  
pp. E89-E95 ◽  
Author(s):  
D. L. DeVol ◽  
P. Rotwein ◽  
J. L. Sadow ◽  
J. Novakofski ◽  
P. J. Bechtel
Keyword(s):  
Gene Expression ◽  
Skeletal Muscle ◽  
Growth Factor ◽  
Muscle Growth ◽  
Experimental Period ◽  
Mrna Levels ◽  
Insulin Like Growth Factor ◽  
Muscle Weight ◽  
Skeletal Muscle Growth ◽  
Igf I

We have investigated the hypothesis that there is local regulation of insulin-like growth factor (IGF) gene expression during skeletal muscle growth. Compensatory hypertrophy was induced in the soleus, a predominantly slow-twitch muscle, and plantaris, a fast-twitch muscle, in 11- to 12-wk-old female Wistar rats by unilateral cutting of the distal gastrocnemius tendon. Animals were killed 2, 4, or 8 days later, and muscles of the nonoperated leg served as controls. Muscle weight increased throughout the experimental period, reaching 127% (soleus) or 122% (plantaris) of control values by day 8. In both growing muscles, IGF-I mRNA, quantitated by a solution-hybridization nuclease-protection assay, rose by nearly threefold on day 2 and remained elevated throughout the experimental period. IGF-II mRNA levels also increased over controls. A more dramatic response was seen in hypophysectomized rats, where IGF-I mRNA levels rose by 8- to 13-fold, IGF-II values by 3- to 7-fold, and muscle mass increased on day 8 to 149% (soleus) or 133% (plantaris) of the control contralateral limb. These results indicate that signals propagated during muscle hypertrophy enhance the expression of both IGF genes, that modulation of IGF-I mRNA levels can occur in the absence of growth hormone, and that locally produced IGF-I and IGF-II may play a role in skeletal muscle growth.

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