Platelet Reactivity in Diabetic Patients Subjected to Acute Exercise Stress Test

2010 ◽  
Vol 42 ◽  
pp. 137
Author(s):  
Mickey Scheinowitz ◽  
Rajbabu Pakala ◽  
Itsik Ben-Dor ◽  
Sara D. Collins ◽  
Soha Ahmad ◽  
...  
Keyword(s):  
Acute Exercise ◽  
Platelet Reactivity ◽  
Stress Test ◽  
Exercise Stress Test ◽  
Exercise Stress ◽  
Diabetic Patients

Platelet reactivity in diabetic patients subjected to acute exercise stress test

2011 ◽  
Vol 12 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Mickey Scheinowitz ◽  
Rajbabu Pakala ◽  
Itsik Ben-Dor ◽  
Gilles Lemesle ◽  
Rebecca Torguson ◽  
...  
Keyword(s):  
Acute Exercise ◽  
Platelet Reactivity ◽  
Stress Test ◽  
Exercise Stress Test ◽  
Exercise Stress ◽  
Diabetic Patients

P4408Cardiovascular response in diabetic patients submitted to treadmill electrocardiographic exercise stress test

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
G Faia Carvalho Dias ◽  
M Oliveira ◽  
B Faria ◽  
P Von Hafe ◽  
A F Cardoso ◽  
...  
Keyword(s):  
Antihypertensive Drugs ◽  
Cardiovascular Response ◽  
Stress Test ◽  
Recovery Period ◽  
Exercise Stress Test ◽  
Exercise Stress ◽  
Control Group ◽  
Diabetic Patients ◽  
Chronotropic Response ◽  
Response To Exercise

Abstract Introduction Diabetes mellitus (DM) is an entity commonly associated with neuropathy, a factor that may have repercussions on the cardiovascular system, specifically in its capacity to respond to stimuli. Objectives To evaluate the cardiovascular response to exercise in diabetic patients, comparing it with a control group. Methods Patients who underwent treadmill eletrocardiographic exercise stress test (EST) between January 2016 and November 2018 without the influence of negative chronotropic medication were included. Results A total of 187 patients were identified, having a mean age of 57±13 years, of whom 120 (64%) were of the male gender. Eighty-four (45%) were diabetic. The group of diabetic patients had a higher prevalence of arterial hypertension, however the number of classes of antihypertensive drugs was not significantly different between diabetic and non-diabetic patients. There were no significant differences in the remaining demographic variables. Patients with DM presented lower maximal heart rates (HR) (141±14 vs 148±19 beats/minute, p=0.015), lower HT reserve (59±16 vs 67±21 beats/minute, p=0.005), as well as a lower rate of HR fall in the recovery period (13±5 vs 16±5 beats/minute2, p<0.001). Total EST time was also lower in diabetic patients (median 7.0 IQR=3 vs 7.3 IQR=3.5 minutes, p=0.044). Additionally, the number of years since the time of diagnosis of DM was inversely correlated with the degree of increase in systolic blood pressure (SBP) with exercise (r=−0.22, p=0.045), and the pre-test SBP (median 135 IQR=24 vs 130 IQR=20 mmHg, p=0.048) and post-test SBP (median 150 IQR=20 vs 140 IQR=25 mmHg, p=0.007) were higher in patients with DM. Discussion In this study it was found that patients with DM present an impaired chronotropic response, both in exercise and recovery periods, and it was observed that the capacity to increase SBP is inversely correlated to the duration of DM. These data may reflect the neuropathic involvement in DM and its influence in the cardiovascular response to exercise.

scholarly journals Heart rate variability and turbulence to determine true coronary artery disease in patients with ST segment depression without angina during exercise stress testing

2011 ◽  
Vol 34 (6) ◽  
pp. 349 ◽  
Author(s):  
Atac Celik ◽  
Ahmet Ozturk ◽  
Kerem Ozbek ◽  
Hasan Kadi ◽  
Fatih Koc ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Rate ◽  
Coronary Artery ◽  
Stress Test ◽  
Exercise Stress Test ◽  
Exercise Stress ◽  
Diabetic Patients ◽  
St Segment ◽  
Group 3 ◽  
Artery Disease

Purpose: ST segment depression without angina during an exercise stress test causes diagnostic problems, particularly in non-diabetic patients. Heart rate variability (HRV) and heart rate turbulence (HRT) are used to evaluate the changes in cardiac autonomic functions and are also both decreased in patients with coronary artery disease. The aim of this study was determine the values of HRV and HRT that discriminate true coronary artery disease from false positive stress test results. Methods: Ninety non-diabetic patients who underwent diagnostic coronary angiography (CA) due to suspected coronary artery disease after ST segment depression without angina during an exercise stress test were enrolled in the study. Prior to CA, 24 hour ambulatory electrocardiogram recordings were taken and HRV and HRT parameters were calculated. Results: Patients were divided into three groups according to the severity of their coronary lesions: (group 1 normal, group 2 non-obstructive and group 3 obstructive. There were no differences among the groups with regards to age, sex, medical history, medications, systolic and diastolic blood pressures, body mass index, fasting glucose, anemia and thyroid status, lipid profile and creatinine clearance. HRV parameters and turbulence slope (TS) were significantly lower while turbulence onset (TO) was significantly higher in group 3 than groups 1 and 2. According to the cut-off values calculated using ROC analysis, SDNN≤69.63 msec, TO > 0.14%, and TS≤2.78 msec/RR have high diagnostic accuracy for predicting obstructive coronary artery disease. Conclusion: HRV and HRT parameters may provide additional information for discriminating between patients who do and do not truly need CA.

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